Alzheimer's disease

European Journal of Neurology - Tập 25 Số 1 - Trang 59-70 - 2018
Chris Lane1, John Hardy2, Jonathan M. Schott1
1Dementia Research Centre, UCL Institute of Neurology, London, UK
2Reta Lila, Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK

Tóm tắt

Alzheimer's disease, the commonest cause of dementia, is a growing global health concern with huge implications for individuals and society. In this review, current understanding of the epidemiology, genetics, pathology and pathogenesis of Alzheimer's disease is outlined, before its clinical presentation and current treatment strategies are discussed. Finally, the review discusses how our enhanced understanding of Alzheimer pathogenesis, including the recognition of a protracted preclinical phase, is informing new therapeutic strategies with the aim of moving from treatment to prevention.

Từ khóa


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Thông tin xuất bản

European Journal of Neurology

Tập 25 Số 1

59-70

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