Advanced Oxidation Protein Products, Parathyroid Hormone and Vascular Calcification in Uremia

Blood Purification - Tập 20 Số 5 - Trang 494-497 - 2002
Tilman B. Drüeke1, Ziad A. Massy1
1Inserm U507 et Service de Néphrologie, Hôpital Necker, Paris, France

Tóm tắt

Vascular calcification is a frequent complication of uremic patients. In addition to classical risk factors such as age, male gender, smoking, inflammation, hypertension, dyslipidemia, and diabetes, which also exist in the general population, patients with chronic renal failure have other risk factors such as oxidative stress, inflammation, hyperparathyroidism, hypoparathyroidism, hypercalcemia, hyperphosphatemia, and overtreatment with calcium and vitamin D. These latter risk factors may even have a better predictive value than classical risk factors for coronary heart disease in uremic patients.

Từ khóa


Tài liệu tham khảo

10.1161/hc0302.102610

10.1056/NEJM200005183422003

10.1097/00000441-199906000-00006

10.1161/hc0502.102969

10.1038/386078a0