Adjuvant γ-Knife Radiosurgery for a Resected Suprasellar Pituitary Adenoma with Atypical Immunohistochemistry: Case Report

Journal of Radiosurgery - Tập 2 - Trang 33-39 - 1999
Gregory M. M Videtic1,2, Kenneth J. Levin1, Lucia Zamorano3, William J. Kupsky4
1Gershenson Radiation Oncology Center, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit
2Department of Radiation Oncology, London Regional Cancer Centre, E., London, Canada
3Department of Neurological Surgery, Wayne State University, Detroit
4Department of Pathology, Wayne State University, Detroit

Tóm tắt

A resected suprasellar mass was found to be an ectopic pituitary adenoma on light microscopy, but immunohistochemistry revealed unusual staining patterns. Residual disease was demonstrated on postoperative studies and γ-knife radiosurgery was used for treatment. The literature on ectopic pituitary tumors was reviewed. We concluded that postoperative stereotactic radiosurgery (SRS) for ectopic, suprasellar pituitary adenomas (and variants thereof) is an appropriate management option for persistent disease.

Tài liệu tham khảo

Erdheim J: Ueber einen Hypophysentumor von ungewoehnlichem Sitz. Beitr Path Anat 46:233–240, 1909 Matsumura A, Meguro K, Doi M, Tsurushima H, Tomono Y: Suprasellar ectopic pituitary adenoma: Case report and review of the literature. Neurosurgery 26:681–685, 1990 Stephanian E, Lunsford LD, Coffey RJ, Bissonnette DJ, Flickinger JC: Gamma knife surgery for sellar and suprasellar tumors. Neurosurg Clin North Am 3:207–218, 1992 Hamada J, Seto H, Miura M, Kuratsu J, Ushio Y: Suprasellar pituitary adenoma arising from the pars tuberalis. Neurosurgery 27:647–649, 1990 Khono M, Sasaki T, Narita Y, Teramoto A, Takakura K: Suprasellar ectopic pituitary adenoma: Case report. Neurol Med Chir (Tokyo) 34:538–542, 1994 Nagatani T, Shibuya M, Suzuki Y, Saito K, Yoshida J: Suprasellar ectopic pituitary adenoma. Acta Neurochir 139:94–95, 1997 Rothman LM, Sher J, Quencer RM, Tenner MS: Intracranial ectopic adenoma: Case report. J Neurosurg 44:96–99, 1976 Hori A: Suprasellar peri-infundibular ectopic adenohypophysis in fetal and adult brains. J Neurosurg 63:113–115, 1985 Lloyd RV: Ectopic pituitary adenomas. In Surgical Pathology of the Pituitary Gland, RV Lloyd (ed). Philadelphia, W.B. Saunders Co., 1993, pp. 116–212 Hofler H, Walter GF, Denk H: Immunocytochemistry of folliculostellate cells in normal human adenohypophyses and in pituitary adenomas. Acta Neuropathol 65:35–40, 1984 Kamal T, Kalman K, Laws ER: Pituitary tumors. In Cancer of the Nervous System, PM Black, JS Loeffler (eds). Cambridge, Mass., Blackwell Science, 1997, pp. 363–403 Tsang RW, Brierley JD, Panzarella T, Gospodarowicz MK, Sutcliffe SB, Simpson WJ: Radiation therapy for pituitary adenoma: Treatment outcome and prognostic factors. Int J Radiat Oncol Biol Phys 30:557–565, 1994 Flickinger KC, Kondziolka D, Lunsford LD: Radiosurgery of benign lesions. Semin Radiat Oncol 5:220–224, 1995