Adiponectin: một adipocytokin chính trong hội chứng chuyển hóa
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Flegal, 2002, Prevalence and trends in obesity among US adults, 1999–2000, JAMA, J. Am. Med. Assoc., 288, 1723, 10.1001/jama.288.14.1723
Reaven, 1988, Role of insulin resistance in human disease, Diabetes, 37, 1595, 10.2337/diab.37.12.1595
Kaplan, 1989, The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension, Arch. Intern. Med., 149, 1514, 10.1001/archinte.1989.00390070054005
Matsuzawa, 1997, Pathophysiology and molecular mechanisms of visceral fat syndrome: the Japanese experience, Diabetes Metab. Rev., 13, 3, 10.1002/(SICI)1099-0895(199703)13:1<3::AID-DMR178>3.0.CO;2-N
National Cholesterol Education Program, 2001, Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III), JAMA, J. Am. Med. Assoc, 285, 2486, 10.1001/jama.285.19.2486
Despres, 1989, Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women, Diabetes, 38, 304, 10.2337/diab.38.3.304
Fujioka, 1987, Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity, Metab., Clin. Exp., 36, 54, 10.1016/0026-0495(87)90063-1
Kanai, 1990, Close correlation of intra-abdominal fat accumulation to hypertension in obese women, Hypertension, 16, 484, 10.1161/01.HYP.16.5.484
Zhang, 1994, Positional cloning of the mouse obese gene and its human homologue, Nature (London), 372, 425, 10.1038/372425a0
Hotamisligil, 1993, Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance, Science, 259, 87, 10.1126/science.7678183
Shimomura, 1996, Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity, Nat. Med., 2, 800, 10.1038/nm0796-800
Steppan, 2001, The hormone resistin links obesity to diabetes, Nature (London), 409, 307, 10.1038/35053000
Maeda, 1996, cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1), Biochem. Biophys. Res. Commun., 221, 286, 10.1006/bbrc.1996.0587
Maeda, 1997, Analysis of an expression profile of genes in the human adipose tissue, Gene, 190, 227, 10.1016/S0378-1119(96)00730-5
Arita, 1999, Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity, Biochem. Biophys. Res. Commun., 257, 79, 10.1006/bbrc.1999.0255
Kissebah, 2000, Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome, Proc. Natl. Acad. Sci. U.S.A., 97, 14478, 10.1073/pnas.97.26.14478
Takahashi, 2000, Genomic structure and mutations in adipose-specific gene, adiponectin, Int. J. Obes. Relat. Metab. Disord., 24, 861, 10.1038/sj.ijo.0801244
Shapiro, 1998, The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor, Curr. Biol., 8, 335, 10.1016/S0960-9822(98)70133-2
Scherer, 1995, A novel serum protein similar to C1q, produced exclusively in adipocytes, J. Biol. Chem., 270, 26746, 10.1074/jbc.270.45.26746
Hu, 1996, AdipoQ is a novel adipose-specific gene dysregulated in obesity, J. Biol. Chem., 271, 10697, 10.1074/jbc.271.18.10697
Nakano, 1996, Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma, J. Biochem. (Tokyo), 120, 803, 10.1093/oxfordjournals.jbchem.a021483
Arita, 2002, Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell, Circulation, 105, 2893, 10.1161/01.CIR.0000018622.84402.FF
Pajvani, 2003, Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity, J. Biol. Chem., 278, 9073, 10.1074/jbc.M207198200
Fruebis, 2001, Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice, Proc. Natl. Acad. Sci. U.S.A., 98, 2005, 10.1073/pnas.98.4.2005
Hotta, 2001, Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys, Diabetes, 50, 1126, 10.2337/diabetes.50.5.1126
Ryo, 2004, Adiponectin as a biomarker of the metabolic syndrome, Circ. J., 68, 975, 10.1253/circj.68.975
Cnop, 2003, Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex, Diabetologia, 46, 459, 10.1007/s00125-003-1074-z
Yatagai, 2003, Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men, Endocr. J., 50, 233, 10.1507/endocrj.50.233
Ouchi, 1999, Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin, Circulation, 100, 2473, 10.1161/01.CIR.100.25.2473
Hotta, 2000, Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients, Arterioscler., Thromb., Vasc. Biol., 20, 1595, 10.1161/01.ATV.20.6.1595
Kumada, 2003, Association of hypoadiponectinemia with coronary artery disease in men, Arterioscler., Thromb., Vasc. Biol., 23, 85, 10.1161/01.ATV.0000048856.22331.50
Zoccali, 2002, Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease, J. Am. Soc. Nephrol., 13, 134, 10.1681/ASN.V131134
Pischon, 2004, Plasma adiponectin levels and risk of myocardial infarction in men, JAMA, J. Am. Med. Assoc., 291, 1730, 10.1001/jama.291.14.1730
Schulze, 2005, Adiponectin and future coronary heart disease events among men with type 2 diabetes, Diabetes, 54, 534, 10.2337/diabetes.54.2.534
Kojima, 2003, The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction, Heart, 89, 667, 10.1136/heart.89.6.667
Nakamura, 2004, Implications of plasma concentrations of adiponectin in patients with coronary artery disease, Heart, 90, 528, 10.1136/hrt.2003.011114
Libby, 1999, Novel inflammatory markers of coronary risk: theory versus practice, Circulation, 100, 1148, 10.1161/01.CIR.100.11.1148
Ouchi, 2003, Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue, Circulation, 107, 671, 10.1161/01.CIR.0000055188.83694.B3
Matsubara, 2003, Decreased plasma adiponectin concentrations in women with low-grade C-reactive protein elevation, Eur. J. Endocrinol., 148, 657, 10.1530/eje.0.1480657
Tchernof, 2002, Weight loss reduces C-reactive protein levels in obese postmenopausal women, Circulation, 105, 564, 10.1161/hc0502.103331
Lindsay, 2005, Adiponectin and coronary heart disease: the Strong Heart Study, Arterioscler., Thromb., Vasc. Biol., 25, e15, 10.1161/01.ATV.0000153090.21990.8c
Lawlor, 2005, Plasma adiponectin levels are associated with insulin resistance but do not predict future risk of coronary heart disease in women, J. Clin. Endocrinol. Metab., 90, 5677, 10.1210/jc.2005-0825
Lindsay, 2002, Adiponectin and development of type 2 diabetes in the Pima Indian population, Lancet, 360, 57, 10.1016/S0140-6736(02)09335-2
Daimon, 2003, Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: the Funagata study, Diabetes Care, 26, 2015, 10.2337/diacare.26.7.2015
Snehalatha, 2003, Plasma adiponectin is an independent predictor of type 2 diabetes in Asian indians, Diabetes Care, 26, 3226, 10.2337/diacare.26.12.3226
Yamamoto, 2004, Adiponectin, an adipocyte-derived protein, predicts future insulin resistance: two-year follow-up study in Japanese population, J. Clin. Endocrinol. Metab., 89, 87, 10.1210/jc.2003-031163
Choi, 2004, Serum adiponectin concentrations predict the developments of type 2 diabetes and the metabolic syndrome in elderly Koreans, Clin. Endocrinol., 61, 75, 10.1111/j.1365-2265.2004.02063.x
Adamczak, 2003, Decreased plasma adiponectin concentration in patients with essential hypertension, Am. J. Hypertens., 16, 72, 10.1016/S0895-7061(02)03197-7
Iwashima, 2004, Hypoadiponectinemia is an independent risk factor for hypertension, Hypertension, 43, 1318, 10.1161/01.HYP.0000129281.03801.4b
Matsubara, 2002, Decreased plasma adiponectin concentrations in women with dyslipidemia, J. Clin. Endocrinol. Metab., 87, 2764, 10.1210/jcem.87.6.8550
Kazumi, 2004, Serum adiponectin is associated with high-density lipoprotein cholesterol, triglycerides, and low-density lipoprotein particle size in young healthy men, Metab., Clin. Exp., 53, 589, 10.1016/j.metabol.2003.12.008
von Eynatten, 2004, Decreased plasma lipoprotein lipase in hypoadiponectinemia: an association independent of systemic inflammation and insulin resistance, Diabetes Care, 27, 2925, 10.2337/diacare.27.12.2925
Hulthe, 2003, Low adipocyte-derived plasma protein adiponectin concentrations are associated with the metabolic syndrome and small dense low-density lipoprotein particles: atherosclerosis and insulin resistance study, Metab., Clin. Exp., 52, 1612, 10.1016/S0026-0495(03)00313-5
Schulze, 2004, Relationship between adiponectin and glycemic control, blood lipids, and inflammatory markers in men with type 2 diabetes, Diabetes Care, 27, 1680, 10.2337/diacare.27.7.1680
Vionnet, 2000, Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24, Am. J. Hum. Genet., 67, 1470, 10.1086/316887
Kondo, 2002, Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome, Diabetes, 51, 2325, 10.2337/diabetes.51.7.2325
Ohashi, 2004, Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease, J. Am. Coll. Cardiol., 43, 1195, 10.1016/j.jacc.2003.10.049
Kishida, 2003, Disturbed secretion of mutant adiponectin associated with the metabolic syndrome, Biochem. Biophys. Res. Commun., 306, 286, 10.1016/S0006-291X(03)00940-9
Stumvoll, 2002, Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes, Diabetes, 51, 37, 10.2337/diabetes.51.1.37
Hara, 2002, Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population, Diabetes, 51, 536, 10.2337/diabetes.51.2.536
Waki, 2003, Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin, J. Biol. Chem., 278, 40352, 10.1074/jbc.M300365200
Okamoto, 2000, An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls, Horm. Metab. Res., 32, 47, 10.1055/s-2007-978586
Ouchi, 2001, Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages, Circulation, 103, 1057, 10.1161/01.CIR.103.8.1057
Ouchi, 2000, Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-κB signaling through a cAMP-dependent pathway, Circulation, 102, 1296, 10.1161/01.CIR.102.11.1296
Yokota, 2000, Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages, Blood, 96, 1723, 10.1182/blood.V96.5.1723
Kumada, 2004, Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages, Circulation, 109, 2046, 10.1161/01.CIR.0000127953.98131.ED
Matsuda, 2002, Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis, J. Biol. Chem., 277, 37487, 10.1074/jbc.M206083200
Okamoto, 2002, Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice, Circulation, 106, 2767, 10.1161/01.CIR.0000042707.50032.19
Yamauchi, 2003, Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis, J. Biol. Chem., 278, 2461, 10.1074/jbc.M209033200
Luscher, 1994, The endothelium and cardiovascular disease: a complex relation, N. Engl. J. Med., 330, 1081, 10.1056/NEJM199404143301511
Vita, 2002, Endothelial function: a barometer for cardiovascular risk?, Circulation, 106, 640, 10.1161/01.CIR.0000028581.07992.56
Ouchi, 2003, Association of hypoadiponectinemia with impaired vasoreactivity, Hypertension, 42, 231, 10.1161/01.HYP.0000083488.67550.B8
Shimabukuro, 2003, Hypoadiponectinemia is closely linked to endothelial dysfunction in man, J. Clin. Endocrinol. Metab., 88, 3236, 10.1210/jc.2002-021883
Tan, 2004, Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation, J. Clin. Endocrinol. Metab., 89, 765, 10.1210/jc.2003-031012
Fernandez-Real, 2004, Adiponectin is associated with vascular function independent of insulin sensitivity, Diabetes Care, 27, 739, 10.2337/diacare.27.3.739
Shetty, 2004, Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes, Diabetes Care, 27, 2450, 10.2337/diacare.27.10.2450
Singhal, 2005, Adiponectin predicts insulin resistance but not endothelial function in young, healthy adolescents, J. Clin. Endocrinol. Metab., 90, 4615, 10.1210/jc.2005-0131
Buras, 2005, Troglitazone-induced changes in adiponectin do not affect endothelial function in diabetes, Obes. Res., 13, 1167, 10.1038/oby.2005.138
Ouchi, 2004, Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells, J. Biol. Chem., 279, 1304, 10.1074/jbc.M310389200
Shibata, 2004, Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling, J. Biol. Chem., 279, 28670, 10.1074/jbc.M402558200
Chen, 2003, Adiponectin stimulates production of nitric oxide in vascular endothelial cells, J. Biol. Chem., 278, 45021, 10.1074/jbc.M307878200
Motoshima, 2004, Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL, Biochem. Biophys. Res. Commun., 315, 264, 10.1016/j.bbrc.2004.01.049
Ilercil, 2001, Relationship of impaired glucose tolerance to left ventricular structure and function: The Strong Heart Study, Am. Heart J., 141, 992, 10.1067/mhj.2001.115302
Rutter, 2003, Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study, Circulation, 107, 448, 10.1161/01.CIR.0000045671.62860.98
Shibata, 2004, Adiponectin-mediated modulation of hypertrophic signals in the heart, Nat. Med., 10, 1384, 10.1038/nm1137
Hong, 2004, Associations among plasma adiponectin, hypertension, left ventricular diastolic function and left ventricular mass index, Blood Press., 13, 236, 10.1080/08037050410021397
Berg, 2001, The adipocyte-secreted protein Acrp30 enhances hepatic insulin action, Nat. Med., 7, 947, 10.1038/90992
Yamauchi, 2002, Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase, Nat. Med., 8, 1288, 10.1038/nm788
Tomas, 2002, Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation, Proc. Natl. Acad. Sci. U.S.A., 99, 16309, 10.1073/pnas.222657499
Maeda, 2002, Diet-induced insulin resistance in mice lacking adiponectin/ACRP30, Nat. Med., 8, 731, 10.1038/nm724
Kubota, 2002, Disruption of adiponectin causes insulin resistance and neointimal formation, J. Biol. Chem., 277, 25863, 10.1074/jbc.C200251200
Yang, 2001, Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin, J. Clin. Endocrinol. Metab., 86, 3815, 10.1210/jcem.86.8.7741
Esposito, 2003, Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial, JAMA, J. Am. Med. Assoc., 289, 1799, 10.1001/jama.289.14.1799
Kobayashi, 2004, Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin, Circ. Res., 94, e27, 10.1161/01.RES.0000119921.86460.37
Nagasawa, 2002, Effects of soy protein diet on the expression of adipose genes and plasma adiponectin, Horm. Metab. Res., 34, 635, 10.1055/s-2002-38254
Nagasawa, 2003, Divergent effects of soy protein diet on the expression of adipocytokines, Biochem. Biophys. Res. Commun., 311, 909, 10.1016/j.bbrc.2003.10.087
Nagao, 2003, Conjugated linoleic acid enhances plasma adiponectin level and alleviates hyperinsulinemia and hypertension in Zucker diabetic fatty (fa/fa) rats, Biochem. Biophys. Res. Commun., 310, 562, 10.1016/j.bbrc.2003.09.044
Shimada, 2004, Oolong tea increases plasma adiponectin levels and low-density lipoprotein particle size in patients with coronary artery disease, Diabetes Res. Clin. Pract., 65, 227, 10.1016/j.diabres.2004.01.003
Maeda, 2001, PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein, Diabetes, 50, 2094, 10.2337/diabetes.50.9.2094
Yu, 2002, The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects, Diabetes, 51, 2968, 10.2337/diabetes.51.10.2968
Yang, 2002, Synthetic peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients, Diabetes Care, 25, 376, 10.2337/diacare.25.2.376
Hirose, 2002, Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes, Metab., Clin. Exp., 51, 314, 10.1053/meta.2002.30506
Combs, 2002, Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: a potential mechanism of insulin sensitization, Endocrinology, 143, 998, 10.1210/endo.143.3.8662
Dzau, 2002, Pathophysiologic and therapeutic importance of tissue ACE: a consensus report, Cardiovasc. Drugs Ther., 16, 149, 10.1023/A:1015709617405
Velloso, 1996, Cross-talk between the insulin and angiotensin signaling systems, Proc. Natl. Acad. Sci. U.S.A., 93, 12490, 10.1073/pnas.93.22.12490
Furuhashi, 2003, Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension, Hypertension, 42, 76, 10.1161/01.HYP.0000078490.59735.6E
Nielsen, 2004, Increased plasma adiponectin in losartan-treated type 1 diabetic patients. a mediator of improved insulin sensitivity?, Horm. Metab. Res., 36, 194, 10.1055/s-2004-814346
Koh, 2004, Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients, Circulation, 110, 3687, 10.1161/01.CIR.0000143085.86697.13
Yamauchi, 2003, Cloning of adiponectin receptors that mediate antidiabetic metabolic effects, Nature (London), 423, 762, 10.1038/nature01705
Tsuchida, 2004, Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity, J. Biol. Chem., 279, 30817, 10.1074/jbc.M402367200
Civitarese, 2004, Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes, Diabetologia, 47, 816, 10.1007/s00125-004-1359-x
Chinetti, 2004, Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR, Biochem. Biophys. Res. Commun., 314, 151, 10.1016/j.bbrc.2003.12.058
Tan, 2005, Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy, Diabetologia, 48, 1585, 10.1007/s00125-005-1835-y
Hammarstedt, 2005, Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects, Diabetologia, 48, 96, 10.1007/s00125-004-1612-3
Narasimhan, 2005, Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor, Mol Cell, 17, 171, 10.1016/j.molcel.2004.11.050
Hug, 2004, T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin, Proc. Natl. Acad. Sci. U.S.A., 101, 10308, 10.1073/pnas.0403382101
Miyoshi, 2003, Association of serum adiponectin levels with breast cancer risk, Clin. Cancer Res., 9, 5699
Kamada, 2003, Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin, Gastroenterology, 125, 1796, 10.1053/j.gastro.2003.08.029
Oshima, 2005, Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast, Biochem. Biophys. Res. Commun., 331, 520, 10.1016/j.bbrc.2005.03.210
