Himanshu Gupta1,2, Simon Beshara3,2, Aristeidis H. Katsanos1,2, Tushar Patil4, Saeed Alzahrani1,2, Jerry Yeou-Wei Chen1,2, Abdulrahman Alharbi1,2, Nasim Zamir5, Kelvin Ng1,2, Carlos S. Kase4, Ashkan Shoamanesh1,2
1Division of Neurology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
2Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
3Division of Neurology, Queen's University, Kingston, Ontario, Canada
4School of Medicine, Emory University, Atlanta, GA, United States
5College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Tóm tắt
ABSTRACT:Hyperglycemia is reported to predict worse outcome in patients with stroke, including intracerebral hemorrhage (ICH). In 83 consecutive cases of ICH at a tertiary stroke center, hyperglycemia (serum glucose >7 mmol/L) compared to normoglycemia at presentation was associated with higher rates of in-hospital mortality (51.2% vs. 26.2%, OR 2.3, CI 1.2–7.6, p = 0.02). The association with in-hospital mortality withstood adjustment for age, ICH volume, intraventricular hemorrhage, and infratentorial ICH location, but not baseline Glasgow Coma Scale. Acute hyperglycemia is associated with in-hospital mortality in spontaneous ICH patients, though this may be an indirect, rather than a causal relationship.
