Activation of the Field CAI of the Hippocampus by Septal Stimulation

Wiley - Tập 51 Số 1 - Trang 29-40 - 1961
P. Andersen1, Helce Bruland1, Bircer R. Kaada1
1Neurophysiological Laboratory at the Anatomical Institute, University of Oslo, Norway

Tóm tắt

Abstract

Andersen P., H. Bruland B. R. Kaada. Activation of the field CA1 of the hippocampus by septal stimulation.

In rabbits under urethane‐chloralose anesthesia the existence of a septo‐hippocampal projection has been verified by the evoked potential method. Its origin is the magnocellular medial septal nucleus. These septo‐fugal fibres activate the basal parts of the apical dendrites and/or the soma of the CAI neurons, probably by a mono‐synaptic route. By repetitive stimulation and by strychnine the depolarized area of the CAI neurons may increase, by anoxia it may decrease. Thus, according to the excitability level, a smaller or greater part of the apical dendrites may initiate spikes of an all‐or‐none character.

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