Độ chính xác của giá trị chọn giống gen trong bò thịt American Angus sử dụng phân cụm K-means cho xác thực chéo
Tóm tắt
Chọn giống gen là một công nghệ mới phát triển đang bắt đầu cách mạng hóa việc chăn nuôi động vật. Mục tiêu của nghiên cứu này là ước tính ảnh hưởng của dấu hiệu gen để xây dựng các phương trình dự đoán cho giá trị gen trực tiếp cho 16 tính trạng được ghi nhận thường xuyên ở bò thịt American Angus và định lượng độ chính xác tương ứng của dự đoán.
Các giá trị chọn giống ước tính không hồi quy được sử dụng làm quan sát trong một phân tích có trọng số để xây dựng giá trị gen trực tiếp cho 3570 bò đực đã được genotyping bằng Illumina BovineSNP50 BeadChip. Những con bò này được phân nhóm thành năm nhóm sử dụng phân cụm K-means trên các ước lượng gia phả của mối quan hệ di truyền bổ sung giữa các động vật, với mục tiêu tăng cường quan hệ trong nhóm và giảm quan hệ giữa các nhóm. Tất cả năm tổ hợp của bốn nhóm được sử dụng cho việc huấn luyện mô hình, với xác thực chéo được thực hiện trong nhóm không được sử dụng trong huấn luyện. Các mô hình động vật hai biến được sử dụng cho mỗi tính trạng để ước tính tương quan di truyền giữa các giá trị chọn giống ước tính không hồi quy và các giá trị gen trực tiếp.
Từ khóa
#genomic selection #beef cattle #genetic correlation #K-means clustering #direct genomic valuesTài liệu tham khảo
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