Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
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Bos, 1989, ras oncogenes in human cancer: A review., Cancer Res., 49, 4682
Franklin K.B.J. Paxinos G. (1997) The mouse brain in stereotaxic coordinates. (Academic Press, San Diego, CA).
Hoesche, 1993, The 5′-flanking region of the rat synapsin I gene directs neuron-specific and developmentally regulated reporter gene expression in transgenic mice., J. Biol. Chem., 268, 26494, 10.1016/S0021-9258(19)74341-5
Johnson, 1994, Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function., Mol. Cell. Biol., 14, 641
Kim, 1995, Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes., Oncogene, 11, 325
Klesse, 1998, p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons., J. Neurosci., 18, 10420, 10.1523/JNEUROSCI.18-24-10420.1998
Kolb, 1986, Cryostat sectioning of Golgi-Cox tissue., Stain Technol., 61, 379, 10.3109/10520298609113588
Kraig, 1991, Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein., J. Neurosci., 11, 2187, 10.1523/JNEUROSCI.11-07-02187.1991
Mandell, 1999, ERK/MAP kinase is chronically activated in human reactive astrocytes., Neuroreport, 10, 3567, 10.1097/00001756-199911260-00019
Mullen, 1992, NeuN, a neuronal specific nuclear protein in vertebrates., Development, 116, 201, 10.1242/dev.116.1.201
Nordlund, 1993, Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons., J. Neurosci., 13, 1588, 10.1523/JNEUROSCI.13-04-01588.1993
Nordlund, 1995, Neurofibromin expression and astrogliosis in neurofibromatosis (type 1) brains., J. Neuropathol. Exp. Neurol., 54, 588, 10.1097/00005072-199507000-00013
North K. (1999) Cognitive function and academic performance. in Neurofibromatosis: Phenotype, natural history, and pathogenesis, eds Friedman J.M. Gutmann D.H. MacCollin M. Riccardi V.M. (Johns Hopkins Press, Baltimore, MD), pp 162–189.
Peltonen, 1988, Cellular differentiation and expression of matrix genes in type 1 neurofibromatosis., Lab. Invest., 59, 760
Rabchevsky, 1998, A role for transforming growth factor alpha as an inducer of astrogliosis., J. Neurosci., 18, 10541, 10.1523/JNEUROSCI.18-24-10541.1998
Ramon y Cajal S. (1904) Histology of the nervous system. (Oxford University Press, New York and UK).
Riccardi V.M. (1999) Historical background and introduction. in Neurofibromatosis: phenotype, natural history, and pathogenesis. eds Friedman J.M. Gutmann D.H. MacCollin M. Riccardi V.M. (Johns Hopkins Press, Baltimore, MD), pp 1–25.
Rosenbaum, 1995, Neurofibromin-deficient fibroblasts fail to form perineurium in vitro., Development, 121, 3583, 10.1242/dev.121.11.3583
Schlegel, 1994, Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma., Int. J. Cancer, 56, 72, 10.1002/ijc.2910560114
van der Geer, 1997, Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap., Mol. Cell. Biol., 17, 1840, 10.1128/MCB.17.4.1840
Viskochil D.H. (1999) The structure and function of the NF1 gene: Molecular pathology. in Neurofibromatosis: Phenotype, natural history, and pathogenesis, eds Friedman J.M. Gutmann D.H. MacCollin M. Riccardi V.M. (Johns Hopkins Press, Baltimore, MD), pp 119–141.