AX+/BX− discrimination learning in the fear-potentiated startle paradigm in monkeys

Learning and Memory - Tập 15 Số 2 - Trang 63-66 - 2008
James Winslow1, Pamela L. Noble, Michael Davis
1National Institute of Mental Health, Intramural Research Program, Bethesda, Maryland 20892, USA. [email protected]

Tóm tắt

Individuals with anxiety disorders often do not respond to safety signals and hence continue to be afraid and anxious. Consequently, it is important to develop paradigms in animals that can directly study brain systems involved in learning about, and responding to, safety signals. We previously developed a discrimination procedure in rats of the form AX+/BX−, where cues A and X presented together are paired with an aversive stimulus and cues B and X presented together predict the absence of an aversive stimulus. The present experiment adapted this procedure to the fear-potentiated startle paradigm in rhesus monkeys.

Từ khóa


Tài liệu tham khảo

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Thông tin xuất bản

Learning and Memory

Tập 15 Số 2

63-66

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