A prospective study of the incidence of deep‐vein thrombosis within a defined urban population

Journal of Internal Medicine - Tập 232 Số 2 - Trang 155-160 - 1992
Marie Nordström1, Bengt Lindblad2, David Bergqvist2, Tord Kjellström1
1Department of Medicine, MalmÖ General Hospital, University of Lund, MalmÖ, Sweden
2Department of Surgery, MalmÖ General Hospital, University of Lund, MalmÖ, Sweden

Tóm tắt

In a prospective study all positive phlebographies within the well‐defined population of the city of MalmÖ, Sweden, during 1987 were studied in order to determine the incidence of deep venous thrombosis (DVT). Epidemiological data were analysed for the detection of patient groups at increased risk of DVT. The incidence was found to be equal for both sexes, i.e. 1.6 per 1000 inhabitants and year. Risk factors were found to be in accordance with earlier studies. The median age for men was 66 years, compared to 72 years for women. At diagnosis of DVT, 19% of subjects had a known malignancy and within 1 year 5% (19 cases) developed a new malignancy. Of the men, 29% had postoperative or post‐traumatic (fracture) DVT, compared to 46% of the women. Fewer patients with DVT than expected (39%) belonged to blood group 0 (31%) (P < 0.005). Pulmonary embolism (PE) was clinically suspected in only 5% of cases, and diagnosis was verified scintigraphically in 2% of cases. None of these died of PE, but of 6 patients who were found to have PE at autopsy, four died about 4 weeks after the DVT was diagnosed.

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Tài liệu tham khảo

10.1161/01.CIR.48.4.839

Gjöres JE, 1956, The incidence of venous thrombosis and its sequelae in certain districts of Sweden, Acta Chir Scand, 111, 16

10.1007/978-3-642-68863-8

Nylander G., 1971, Angiography, 1251

Fejfar Z., 1966, Epidemiological aspects of thrombosis and vascular disease, Throm Diath Haemorrh, 16, 5

Kierkegaard A., 1980, Incidence of acute deep vein thrombosis in two districts, Acta Chir Scand, 146, 267

10.1097/00000658-197708000-00006

10.3109/00016348309154217

Greer IA, 1992, Haemostasis and Thrombosis in Obstetrics and Gynaecology, 371

Nylander G., 1977, Earlier and concurrent morbidity of patients with acute lower leg thrombosis, Acta Chir Scand, 143, 425

10.1016/S0140-6736(71)90961-5

10.1016/0021-9150(76)90124-6

VÖlter, 1970, ABO‐Blutgruppen und Erkrankungen, Z Morphol Anthropol, 62, 290, 10.1127/zma/62/1970/290

Trousseau A., 1865, Phlegmasia Alba Dolens, 94

Coon WW, 1973, Recurrence of venous thromboembolism, Surgery, 73, 823

Verstraete M., 1984, Thrombosis, 201

Kelton JG, 1980, Bleeding associated with antithrombotic therapy, Semin Hematol, 17, 259

Letter to the editor, 1988, Management of venous thromboembolism, Lancet, 1, 275

Meade TW, 1983, The thromboembolic disorders; the epidemiology of atheroma and thrombosis, 116