A novel bombesin receptor antagonist (2258U89), potently inhibits bombesin evoked release of gastrointestinal hormones from rats and dogs, in vitro and in vivo
Tài liệu tham khảo
Rivier, 1978, The effect of bombesin and related peptides on prolactin and growth hormone secretion in the rat, Endocrinology, 102, 519, 10.1210/endo-102-2-519
Ghatei, 1982, Bombesin-action on hormones and calcium in man, J. Clin. Endocrinol. Metab., 54, 980, 10.1210/jcem-54-5-980
Guo, 1988, Role of Ca2+ in bombesin-stimulated release of gastrin and somatostatin from isolated perfused rat stomach, Am. J. Physiol., 254, G627
Modlin, 1981, Stimulation of canine pancreatic polypeptide, gastrin and gastric acid secretion by ranatensin, litorin, bombesin and non-apeptide of substance P, Regul. Pept., 1, 279, 10.1016/0167-0115(81)90051-3
May, 1978, Actions of peptides isolated from amphibian skin on pancreatic acinar cells, Am. J. Physiol., 235, E112
Girard, 1984, The contractile effect of bombesin, gastrin-releasing-peptide and various fragments in the rat stomach strip, Eur. J. Pharmacol., 102, 489, 10.1016/0014-2999(84)90570-3
Severi, 1988, Identification of separate bombesin and substance P receptors on isolated muscle cells from canine gallbladder, J. Pharm. Exp. Ther., 245, 195
Brown, 1977, Bombesin: potent effect on thermoregulation in the rat, Science (London), 196, 998
Brown, 1977, Bombesin affect the central nervous system to produce hyperglycemia in rats, Life Sci., 21, 1729, 10.1016/0024-3205(77)90151-5
Folkers, 1984, Biological evaluation of substance P antagonists, Br. J. Pharmacol., 83, 449, 10.1111/j.1476-5381.1984.tb16506.x
Cuttitta, 1985, Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer, Nature (London), 318, 823, 10.1038/316823a0
Willey, 1984, Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells, Exp. Cell Res., 153, 245, 10.1016/0014-4827(84)90466-X
Corps, 1985, A peptide that inhibits the mitogenic stimulation of Swiss 3T3 cells by bombesin or vasopressin, Biochem. J., 231, 781, 10.1042/bj2310781
Narayan, 1990, Specific binding sites and growth effects of bombesin related peptides on mouse colon cancer cells, Cancer Res., 50, 6772
Narayan, 1992, A potent bombesin receptor antagonist inhibits bombesin stimulated growth of mouse colon cancer cells in vitro: Absence of autocrine effects, Cell Growth Diff., 3, 111
von Schrenck, 1990, Potent bombesin receptor antagonists distinguish receptor subtypes, Am. J. Physiol., 259, G468
Coy, 1988, Probing peptide backbone function in bombesin, J. Biol. Chem., 263, 5056, 10.1016/S0021-9258(18)60678-7
Singh, 1990, Molecular characterization of bombesin receptors on rat pancreatic acinar cancer (AR42J) cells, Am. J. Physiol., 258, G803
Saffouri, 1980, Gastrin and somatostatin secretion by perfused rat stomach: functional linkage of antral peptides, Am. J. Physiol., 238, G495
Greeley, 1986, Comparision of the actions of bombesin, gastrin-releasing peotide-27, neuromedin B and gastrin-releasing peptide-10 in causing release of gastrin and gastric inhibitory peptide in rats, 183, 136
Jackson, 1972, Dynamic characteristics of gastrin release, Am. J. Surg., 123, 137, 10.1016/0002-9610(72)90323-6
Guo, 1987, Effect of peptide YY on cephalic, gastric and intestinal phases of gastric acid secretion and on the release of gastrointestinal hormones, Gastroenterology, 92, 1202, 10.1016/S0016-5085(87)91078-X
Greeley, 1984, Insulinotropic and gastrin-releasing action of gastrin-releasing peptide (GRP), Regul. Pept., 8, 97, 10.1016/0167-0115(84)90164-2
Thompson, 1972, Effect of secretin on circulating gastrin, Ann. Surg., 176, 384, 10.1097/00000658-197209000-00014
Wang, 1990, Desmethionine alkylamide bombesin analogues: a new class of bombesin receptor antagonists with potent antisecretory activity in pancreatic acini and antimitoic activity in Swiss 3T3 cells, Biochemistry, 29, 616, 10.1021/bi00455a004
Coy, 1989, Short-chain pseudopeptide bombesin receptor antagonists with enhanced binding affinities for pancreatic acinar and Swiss 3T3 cells display strong antimitotic activity, J. Biol. Chem., 264, 14691, 10.1016/S0021-9258(18)63753-6
Wang, 1990, Des-met carboxyl-terminally modified analogues of bombesin functions as potent bombesin receptor antagonists, partial agonists, or agonists, J. Biol. Chem., 26, 15695, 10.1016/S0021-9258(18)55454-5
Dickson, 1988, Partial agonist activity of the bombesin-receptor antagonist [Leu14-CCH2-NH-Leu13]bombesin in frog peptic cells, Biochem. Biophys. Res. Commun., 157, 1154, 10.1016/S0006-291X(88)80994-X
Rossowski, 1989, Effects of a novel bombesin antagonist analogue on bombesin-stimulated gastric acid secretion and growth hormone release in the pentobarbital anesthetized rat, Scand. J. Gastroenterol., 24, 121, 10.3109/00365528909092249
Heimbrook, 1989, Carboxyl-terminal modification of gastrin releasing peptide derivative generates potent antagonists, J. Biol. Chem., 264, 11258, 10.1016/S0021-9258(18)60457-0
Jensen, 1989, Characterization of ability of various substance P antagonists to inhibit action of bombesin, Am. J. Physiol., 254, G883
Pappas, 1985, Spantide: failure to antagonize bombesin-induced stimulation of gastrin secretion in dogs, Peptides, 6, 1001, 10.1016/0196-9781(85)90335-3