A mixed choroid plexus papilloma and ependymoma

Brain Tumor Pathology - Tập 33 - Trang 147-150 - 2015
Yujin Lee1, Seong Ik Kim1, Seung-Ki kim2, In One Kim3, Sung-Hye Park1,4
1Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea
2Department of Neurosurgery, Seoul National University Children’s Hospital and College of Medicine, Seoul, Republic of Korea
3Department of Radiology, Seoul National University Children’s Hospital and College of Medicine, Seoul, Republic of Korea
4Neuroscience Institute, Seoul National University, College of Medicine, Seoul, Republic of Korea

Tóm tắt

We report a novel case of a mixed choroid plexus papilloma (CPP) and ependymoma with cartilaginous differentiation. This kind of mixed tumor has not been previously reported in the English literature. The patient was a 5-year-old girl, who presented with a 1-week history of fever and numbness of the right lower limb. Magnetic resonance imaging of the brain with gadolinium revealed a heterogeneously enhancing mass in the occipital horn of the left lateral ventricle. Histologically, the tumor showed an intermixed CPP area and a low-grade papillary ependymoma-like area, which was studded with cartilage islands and psammoma bodies. In many foci, direct transition of CPP and ependymoma was observed, but there were no high-grade features. We report this novel case, describe the unique microscopic and immunohistochemical features, and speculate on the pathogenesis.

Tài liệu tham khảo

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Thông tin
Thông tin xuất bản

Brain Tumor Pathology

Tập 33

147-150

Thông tin tác giả