A compilation of antimicrobial susceptibility data from a network of 13 Lebanese hospitals reflecting the national situation during 2015–2016

Springer Science and Business Media LLC - Tập 8 - Trang 1-17 - 2019
Rima Moghnieh1,2, Georges F. Araj3, Lyn Awad4, Ziad Daoud5,6, Jacques E. Mokhbat7,8, Tamima Jisr9, Dania Abdallah4, Nadim Azar10, Noha Irani-Hakimeh6,11, Maher M. Balkis12,13, Mona Youssef14, Gilbert Karayakoupoglou15, Monzer Hamze16, Madonna Matar17,18, Roula Atoui2,19, Edmond Abboud20, Rita Feghali21, Nadine Yared22, Rola Husni7,8
1Department of Internal Medicine, Division of Infectious Diseases, Makassed General Hospital, Beirut, Lebanon
2Faculty of Medicine, Lebanese University, Beirut, Lebanon
3Professor and Director of Clinical Microbiology, Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon
4Pharmacy Department, Makassed General Hospital, Beirut, Lebanon
5Department of Microbiology, Centre Hospitalier du Nord, Zgharta, Lebanon
6Faculty of Medicine and Medical Sciences, University of Balamand, Koura, Lebanon
7Department of Internal Medicine, Division of Infectious Diseases, Lebanese American University-Rizk Hospital, Beirut, Lebanon
8Faculty of Medicine, Lebanese American University, Beirut, Lebanon
9Department of Laboratory Medicine, Makassed General Hospital, Beirut, Lebanon
10Department of Microbiology, Hotel Dieu de France Hospital, Beirut, Lebanon
11Department of Laboratory Medicine, Saint George University Hospital, Beirut, Lebanon
12Department of Internal Medicine, Division of Infectious Diseases, Labib Medical Center, Saida, Lebanon
13Medical Subspecialties Institute – Infectious Diseases, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates
14Department of Internal Medicine, Division of Infectious Diseases, Haykel Hospital, Tripoli, Lebanon
15Department of Microbiology and Molecular diagnostics, Haykel Hospital, Tripoli, Lebanon
16Department of Microbiology, Nini Hospital, Tripoli, Lebanon
17Department of Internal Medicine, Division of Infectious Diseases, Notre Dame de Secours University Hospital, Jbeil, Lebanon
18Faculty of Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon
19Department of Internal Medicine, Zahraa Hospital, Beirut, Lebanon
20Department of Microbiology, The Middle East Institute of Health University Hospital, Mount Lebanon, Lebanon
21Department of Laboratory Medicine, Rafik Hariri University Hospital, Beirut, Lebanon
22Chairperson Internal Medicine, Lebanese University, Beirut, Lebanon

Tóm tắt

There is a lack of official national antimicrobial resistance (AMR) data in Lebanon. Individual hospitals generate their own antibiotic susceptibility data in the form of yearly pamphlets. In this study, antibiotic susceptibility data from 13 hospitals distributed across different governorates of Lebanon were collected to conduct a compilation-based surveillance of AMR in Lebanon for the years 2015–2016. The findings were compared with those of a previous nationwide study in this country conducted between 2011 and 2013 as well as with similar data obtained from the 2015 and 2016 European surveillance reports of AMR. To provide a clear presentation of the AMR situation, mean percent susceptibility of different antibiotic–microbe combinations was calculated. During 2015–2016, the percent susceptibility of Enterobacteriaceae to third-generation cephalosporins and to carbapenems was 59 and 97%, respectively. Among Pseudomonas aeruginosa and Acinetobacter spp., carbapenem susceptibility reached 70 and 12%, respectively. Among Gram positive organisms, the percent susceptibility to methicillin in Staphylococcus aureus was 72%, that to vancomycin in Enterococcus spp. was 98% and that to penicillin in Streptococcus pneumoniae was 75%. Compared with results of 2011–2013, there was an overall trend of decreased susceptibility of bacteria to the tested antibiotics, with a variation of 5 to 10%. The antibiotic susceptibility data from Lebanon were found to be comparable with those from Eastern and South-eastern European countries. This study highlights the need to establish a robust national AMR surveillance system that enables data from Lebanon to be included in global AMR maps.

Tài liệu tham khảo

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