A chemokine regulatory loop induces cholesterol synthesis in lung-colonizing triple-negative breast cancer cells to fuel metastatic growth

Molecular Therapy - Tập 30 - Trang 672-687 - 2022
Bingchen Han1, Felix Alonso-Valenteen2, Zhe Wang3, Nan Deng4, Tian-Yu Lee1, Bowen Gao1, Ying Zhang3, Yali Xu5, Xinfeng Zhang1, Sandrine Billet6, Xuemo Fan7, Stephen Shiao8, Neil Bhowmick6, Lali Medina-Kauwe9, Armando Giuliano1, Xiaojiang Cui1
1Department of Surgery, Samuel Oschin Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
2Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
3Department of Pathology, Shengjing Hospital of China Medical University, Shenyang 110004, China
4Biostatistics and Bioinformatics Research Center, Samuel Oschin Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
5Department of Breast Surgery, Peking Union Medical College Hospital, Beijing 100730, China
6Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
7Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
8Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
9Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA

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