Một Bài Tổng Quan Về Ứng Dụng Dược Liệu Dân Tộc, Hoạt Động Dược Lý, Và Các Thành Phần Sinh Học Của Mangifera indica (Mãng Cầu)

Meran Keshawa Ediriweera1, Kamani Hemamala Tennekoon1, Sameera R. Samarakoon1
1Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90, Cumaratunga Munidasa Mawatha, Colombo 03, Sri Lanka

Tóm tắt

Mangifera indica (họ Anacardiaceae), thường được biết đến với tên gọi là mãng cầu, là một loại cây có sự đa dạng về mặt dược lý, y học dân tộc và hóa học thực vật. Các bộ phận khác nhau của cây M. indica đã được sử dụng trong y học cổ truyền để điều trị các loại bệnh khác nhau, và một số thành phần hóa học sinh học có hoạt tính đã được báo cáo trong M. indica, cụ thể như polyphenol, terpene, sterol, carotenoid, vitamin, và axit amin, v.v. Nhiều nghiên cứu đã chứng minh tiềm năng dược lý của các bộ phận khác nhau của cây mãng cầu như lá, vỏ, thịt quả, rễ và hoa với các tác dụng chống ung thư, chống viêm, chống tiểu đường, chống oxy hóa, kháng khuẩn, kháng nấm, diệt ký sinh trùng, bảo vệ dạ dày, bảo vệ gan, điều biến miễn dịch, chống plasmodium và giảm lipid máu. Trong bài đánh giá này, một nghiên cứu toàn diện về các ứng dụng dược lý dân tộc, hoạt động dược lý, và các hợp chất sinh học của M. indica đã được mô tả.

Từ khóa

#Mãng cầu #dược liệu dân tộc #hoạt động dược lý #hợp chất sinh học #Anacardiaceae

Tài liệu tham khảo

10.1139/G10-005

10.17660/ActaHortic.2004.645.7

10.1016/j.tifs.2016.06.009

Reddy P. V. R., Economic and Ecological Significance of Arthropods in Diversified Ecosystems, 271

Ghuniyal J., 2015, Ethanomedical, chemical, pharmacological, toxicological properties of mangifera indica: a review, International Journal of Pharma Research & Review, 4, 51

10.1002/9781118324097.ch15

10.1016/j.foodchem.2006.06.036

10.1016/j.foodchem.2010.12.026

10.1007/BF02863059

10.1007/BF02861039

10.3852/mycologia.97.1.99

10.1079/9781845934897.0000

Nandwani D., 2006, Grafting of mango cultivars (Mangifera indica l.) in the u.s. virgin islands, Their Culture, Environment, and Use, 441

10.1093/jisesa/iev090

10.1016/j.foodres.2010.11.022

Parvez G. M. M., 2016, Pharmacological activities of mango (Mangifera Indica): A review, Journal of Pharmacognosy and Phytochemistry, 3

Wauthoz N., 2007, Ethnopharmacology of Mangifera indica L. bark and pharmacological studies of its main C-glucosylxanthone, mangiferin, International Journal of Biomedical and Pharmaceutical Sciences, 1, 112

10.9734/EJMP/2017/32342

Khare C. P., 2008, Indian Medicinal Plants: An Illustrated Dictionary

Williams C., 2002, Medicinal Plants in Australia: Plants, Potions and Poisons

Tirtha S. S., 2007, Natural Secrets to Healing, Prevention, and Longevity

Agarwal T., 2008, Impact of iron supplementation on anemia during pregnancy, Age, 4500

Khandare M. S., 2016, Mango (Mangifera indica Linn) A medicinal and holy plant, Journal of Medicinal Plants Studies, 4, 44

Etuk E. U., 2010, Ethnobotanical survey of medicinal plants used for the treatment of Diabetes mellitus in the north western region of Nigeria, Asian Journal of Experimental Biological Sciences, 1, 55

Ene A. C., 2012, Ethnomedicinal survey of plants used by the Kanuris of North-eastern Nigeria, Indian Journal of Traditional Knowledge, 11, 640

Memon A. H., 2008, Common folk medicinal and ethnomedicinal uses of thirty medicinal plants of districts Dadu and Jamshoro, Sindh, Pakistan, Sindh University Research Journal (Science Series), 40, 89

Nisar M. F., 2011, Ethnomedicinal flora of District MandiBahaudin, Pakistan, Middle-East Journal of Scientific Research, 9, 233

10.1186/1746-4269-2-47

Jayaweera D. M. A., 1980, Medicinal plants (Indigenous and exotic) used in Ceylon

10.1021/jf800738r

10.1021/jf0484069

10.1002/ep.12669

10.1248/bpb.21.1389

10.1016/j.scienta.2011.03.015

10.1016/S0899-9007(00)00304-X

10.1007/s11130-006-0035-3

10.1080/87559120903153524

10.1021/jf000025h

10.1080/10408690091189257

10.1016/S0304-4165(97)00006-8

10.1021/jf9911287

Jungalwala F. B., 1963, Carotenoids in mango (Mangifera indica) fruit, Indian Journal of Chemistry, 1

10.1111/j.1365-313X.2011.04520.x

10.1046/j.1439-0418.2001.00510.x

10.1016/S0925-5214(02)00117-5

10.1016/j.foodchem.2014.03.009

10.1021/jf901621m

10.1021/jf0706981

10.1021/cr970464o

10.1016/j.biopha.2017.01.176

10.1016/j.jpba.2014.12.010

10.1016/j.jep.2016.05.047

10.1016/j.fct.2007.05.015

10.1517/13543776.2013.836182

10.1002/biof.1308

10.2174/138955711795305335

10.1016/j.foodchem.2008.02.067

10.1021/jf030218f

Anjaneyulu V., 2000, The triterpenoids and steroids from Mangifera indica Linn, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 39, 883

10.4103/0973-7847.65325

10.1016/S0378-8741(00)00213-0

10.3742/OPEM.2007.7.1.001

10.1016/B978-0-12-374628-3.00034-7

10.1002/9781119014362.ch12

Kalita P., 2014, An overview on mangifera indica: importance and its various pharmacological action, PharmaTutor, 2, 72

10.1016/0009-3084(92)90065-W

Augustin M. A., 1987, Composition of mango seed kernel, Pertanika, 10, 53

10.3390/molecules15117715

10.3390/nu9050525

10.1016/j.foodres.2015.04.018

10.1093/ajcn/74.4.418

10.1021/jf205065x

Thambi P. A., 2016, Antimicrobial efficacy of mango peel powder and formulation of recipes using mango peel powder (Mangifera indica L.), nternational Journal of Home Science, 2, 155

10.1111/ijfs.13341

10.1111/j.1750-3841.2012.02807.x

10.1016/j.foodchem.2009.12.060

10.1111/j.1750-3841.2011.02477.x

10.1016/j.foodchem.2016.05.147

Afifa K., 2014, A comparison with antioxidant and functional properties among five mango (Mangifera indica L.) Varieties in Bangladesh, International Food Research Journal, 21, 1501

10.3844/ajabssp.2014.311.320

Norshazila S., 2010, Antioxidant levels and activities of selected seeds of Malaysian tropical fruits, Malaysian Journal of Nutrition, 16, 149

Pitchaon M., 2011, Antioxidant capacity of extracts and fractions from mango (Mangifera indica Linn.) seed kernels, International Food Research Journal, 18, 523

10.1016/s1995-7645(13)60062-0

10.1101/gad.7.11.2064

10.1126/science.278.5339.860

10.1136/gut.42.4.477

10.1152/ajpgi.00079.2004

10.1002/mc.22484

10.1002/mnfr.201501008

10.3748/wjg.v16.i39.4922

10.1155/2012/967573

10.1016/j.phrs.2003.12.003

10.1002/1099-1573(200102)15:1<18::AID-PTR676>3.0.CO;2-R

10.1016/j.phrs.2003.12.020

10.1002/1099-1573(200009)14:6<424::AID-PTR643>3.0.CO;2-8

10.1016/j.hjb.2016.02.001

10.1155/2014/132097

10.56808/3027-7922.2167

10.1186/s12906-015-0594-7

10.1155/2015/593902

10.1006/bbrc.1998.9075

10.1007/s11060-013-1136-0

10.1002/ptr.2650010110

10.1111/j.1750-3841.2011.02243.x

10.15373/2249555X/OCT2013/121

10.1039/c5ra01911g

10.1211/jpp.59.12.0005

10.3390/molecules19056694

10.4103/0973-1296.153078

Krishnan K., 2014, Cytotoxic activity of bioactive compound 1, 2-benzene Dicarboxylic acid, mono 2-Ethylhexyl Ester extracted from a marine derived Streptomyces sp. VITSJK8, International Journal of Molecular and Cellular Medicine, 3, 246

10.1016/j.bmc.2008.01.049

10.1007/s002040050159

10.1016/0278-6915(95)00077-1

10.1111/j.1749-6632.1998.tb09922.x

10.1016/j.mad.2004.01.007

10.1016/j.phrs.2007.01.012

10.1016/S0031-9422(00)94842-8

10.1021/jf011064b

10.1515/znc-2010-5-603

10.1021/jf063051

10.1016/j.bbagen.2006.04.005

10.1016/j.foodchem.2005.05.033

10.1021/jf5008743

10.1016/j.phytochem.2007.10.013

10.1016/j.foodchem.2012.02.172

10.1111/j.2042-7158.2011.01300.x

10.1016/j.ejphar.2007.04.059

10.1007/s10753-012-9509-7

10.1046/j.1365-2621.2001.00522.x

10.1155/2017/5936239

10.1016/0891-5849(95)02227-9

10.1186/s12883-016-0541-3

10.4161/oxim.2.5.9498

10.1007/bf02535085

10.1016/j.foodchem.2012.04.103

George S., 2011, Antibiotic activity of 2, 3-dihydroxybenzoic acid isolated from Flacourtia inermis fruit against multidrug resistant bacteria, Asian Journal of Pharmaceutical and Clinical Research, 4, 126

10.4315/0362-028X-66.10.1811

10.1104/pp.011019

10.1016/j.anaerobe.2012.04.001

10.4014/jmb.0800.025

10.1002/jsfa.3799

10.1111/j.1472-765X.1993.tb01428.x

10.1016/S0981-9428(02)01470-5

10.1093/jac/dkh046

10.1155/2013/230795

10.1016/j.bmcl.2014.02.017

10.1046/j.1472-765X.2001.00893.x

10.1016/j.antiviral.2005.06.010

Heng M., 1990, Antiviral effect of mangiferin and isomangiferin on herpes simplex virus, Chinese Medical Journal, 103, 160

10.1007/bf01128976

10.1248/bpb.31.903

10.12982/CMUJNS.2014.0038

10.2337/db10-1461

Zheng G., 2004, Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice, In Vivo, 18, 55

10.1016/j.bjp.2015.07.025

10.1016/0041-008X(88)90186-X

10.1021/jf900420g

10.4236/wjns.2013.31004

10.1007/s10886-007-9393-z

Conte A., 2003, Effect of resveratrol and catechin on PC12 tyrosine kinase activities and their synergistic protection from β-amyloid toxicity, Drugs under Experimental and Clinical Research, 29, 243

10.1007/s11596-009-0208-z

10.1002/biof.5520330207

10.1271/bbb.90365

Park I., 2007, Nematicidal activity of plant essential oils and components from Ajowan (Trachyspermum ammi), Allspice (Pimenta dioica) and Litsea (Litsea cubeba) essential oils against pine wood nematode (Bursaphelenchus Xylophilus), Journal of Nematology, 39, 275

10.1007/s12010-008-8440-8

10.2337/diabetes.50.8.1844

FernÃndez-Checa J. C., 1997, Oxidative stress and alcoholic liver disease, Alcohol Research and Health, 21

10.1124/dmd.31.12.1499

10.2174/1568026013395001

10.1080/07315724.2014.887486

10.4103/0973-1296.96553

10.1002/mnfr.200600113

10.1007/s11130-010-0161-9

10.1055/s-0029-1185507

10.1358/mf.2005.27.8.928308

10.3329/jbau.v8i2.7932

10.1056/nejmra993360

10.1016/S0769-2625(84)80105-1

10.1016/j.amjmed.2004.03.040

10.1002/ptr.1656

10.1016/j.intimp.2004.02.003

10.1016/S0378-8741(01)00326-9

10.1016/j.fsi.2006.09.009

10.5530/pc.2016.3.3

10.3322/caac.21395

10.1016/s0140-6736(96)07493-4

Archer M. C., 1980, Cancer-Causing Agents, Canadian Medical Association Journal, 122

World Health WHO handbook for reporting results of cancer treatment Geneva: World Health Organization 1979.

10.1002/1097-0010(20000915)80:12<1744::AID-JSFA725>3.0.CO;2-W

10.1016/j.foodchem.2012.01.053

Corrales-Bernal A., 2014, In vitro and in vivo effects of mango pulp (Mangifera indica cv. Azucar) in colon carcinogenesis, Archivos Latinoamericanos de Nutrición, 64, 16

10.1155/2015/613268

10.1016/j.nutres.2015.06.002

10.1021/jf903161g

10.1080/01635580701613772

10.1111/j.1750-3841.2010.01899.x

10.1186/s12906-015-0575-x

10.3390/ijms16023528

10.1021/acs.jnatprod.6b00381

10.4103/2231-4040.197371

10.9734/BJPR/2016/24004

10.3892/ol.2016.4087

10.1111/jfbc.12294

10.1002/biof.1299

10.1038/nm1145

10.1126/science.257.5073.1064

10.1093/jac/49.1.25

10.1046/j.1365-2672.2000.00969.x

10.1002/fsn3.399

10.1016/S1995-7645(11)60089-8

Alok P., 2013, Antibacterial property of two different varieties of Indian mango (Mangifera indica) kernel extracts at various concentrations against some human pathogenic bacterial strains, Research Journal of Biological Sciences, Research Journal of Biological Sciences, 2, 28

10.3923/jas.2009.3013.3019

10.1016/S0308-8146(00)00126-6

10.9734/JAMPS/2017/31127

Doughari J. H., 2008, In vitro antibacterial activity of crude leaf extracts of Mangifera indica Linn, African Journal of Microbiology Research, 2, 67

Hannan A., 2013, Antibacterial effect of mango (Mangifera indica Linn.) leaf extract against antibiotic sensitive and multi-drug resistant Salmonella typhi, Pakistan Journal of Pharmaceutical Sciences, 26, 715

10.9790/2402-0737478

10.5530/jyp.2014.4.6

Madduluri S., 2013, In vitro evaluation of antibacterial activity of five indigenous plants extract against five bacterial pathogens of human, International Journal of Pharmacy and Pharmaceutical Sciences, 5, 679

SahrawatA. PalS. andShahiS. K. Antibacterial activity of Mangifera indica (mango) leaves against drug resistant bacterial strains 1 Proceedings of the 2013 82–86.

10.4236/aim.2012.24074

10.1007/s00217-001-0485-7

Latha M. S., 2011, Phytochemical investigation and antibacterial activity of Mangifera indica L. var. Rasapuri root extracts, International Journal of Medicinal and Aromatic Plants, 1, 45

10.1016/j.indcrop.2013.04.001

Rakholiya K., 2013, Antimicrobial activity of decoction extracts of residual parts (seed and peels) of Mangifera indica L. var. Kesar against pathogenic and food spoilage microorganism," Microbial pathogens and strategies for combating them: Science, Technology and Education, FORMATEX, 850

Verma S. K., 2015, In vitro Antibacterial Activity and Phytochemical Analysis of Mangifera indica L flower. Extracts against Pathogenic. Microorganisms, Journal of Pharmacology & Clinical Toxicology, 3

Chidozie V. N., 2014, Antibacterial and toxicological effects of the aqueous extract of mangifera indica stem bark on albino rats, Global Journal of Biology, Agriculture and Health Sciences, 3, 237

10.1126/scitranslmed.3004404

10.1093/clinids/20.6.1526

10.1126/science.7702654

Muazu U., 2017, Effects of some plant extracts on some selected fungal species, Journal of Zoological And Bioscience Research, 3

Bautista Banos S., 2002, Torres, Antifungal activity of leaf and stem extracts from various plant species on the incidence of Colletotrichum gloeosporioides of papaya and mango fruit after storage, Mexicana de Fitopatologφa, 20

10.1080/14786419.2015.1115995

10.1016/S0140-6736(06)68653-4

10.1016/j.pt.2003.10.002

Gleick P. H., 2002, Dirty-Water: Estimated Deaths from Water-Related Diseases 2000-2020

10.7439/ijpp.v2i1.380

10.3329/bjvm.v6i2.2333

El-Sherbini G. T., 2013, Anthelmintic activity of unripe Mangifera indica L. (Mango) against Strongyloides stercoralis, International Journal of Current Microbiology and Applied Sciences, 2, 401

10.1002/ptr.1343

10.1007/s12038-008-0076-x

10.1038/nature01097

10.1186/1475-2875-10-S1-S1

10.1002/(SICI)1099-1573(199809)12:6<437::AID-PTR313>3.0.CO;2-C

10.1016/j.jep.2005.01.004

Bidla G., 2004, Antiplasmodial activity of seven plants used in African folk medicine, Indian Journal of Pharmacology, 36, 245

10.1007/s11695-013-1121-x

10.4103/0974-8490.199770

Morsi R. M. Y., 2010, Effect of aqueous extract Mangifera indica leaves, as functional foods, Journal of Applied Sciences Research, 6, 712

Shah K. A., 2010, Antihyperlipidemic activity of Mangifera indica l. leaf extract on rats fed with high cholesterol diet, Der Pharmacia Sinica, 1, 156

Hossain M. S., 2010, Hypolipidemic and hepatoprotective effects of different fractions of ethanolic extract of immature leaves of Mangifera indica (Linn.) in alloxan induced diabetic rats, International Journal of Pharmaceutical Sciences and Research, 1

Venkatalakshmi P., 2011, Antihyperlipidemic and antioxidant activities of Mangifera Indica Linn., in alloxan induced rats, International Journal of Pharmaceutical Sciences Review and Research, 11, 129

Vasant R. A., 2011, Antihyperglycemic and antihyperlipemic effects of Mangifera indica L. in fluoride induced toxicity, Pharmacologyonline, 3, 265

10.1159/000497694

Deepthi B., 2017, A modern review of diabetes mellitus: an annihilatory metabolic disorder, Journal of In Silico & In Vitro Pharmacology, 3, 1

10.1111/1471-0528.14236

Diabetes Prevention Trial–Type 1 Diabetes Study Group, 2002, Effects of insulin in relatives of patients with type 1 diabetes mellitus, New England journal of Medicine, 2002, 1685

10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S

10.2337/diacare.12.8.553

10.1016/j.jep.2017.01.023

10.1007/s13197-015-1963-4

10.1002/jsfa.6778

10.1023/B:QUAL.0000040336.38013.83

10.1002/fsn3.348

Mohammed A., 2017, Anti-diabetic efficacy of young and mature leaf extract of Mangifera indica, Journal of Traditional Medicines, 12, 1

Dineshkumar B., 2010, A comparative study of alpha amylase inhibitory activities of common anti-diabetic plants at Kharagpur 1 block, Journal of Advanced Pharmaceutical Technology & Research, 4, 115

10.1002/(SICI)1099-1573(199909)13:6<504::AID-PTR533>3.0.CO;2-9

Tanko Y., 2012, The effect of methanol leaves extract of Ficus Glumosa on gastrointestinal motility and on castor oil induced diarrhea in laboratory animals, Journal of Natural Product and Plant Resources, 2, 239

Mangola E. N., 1990, Use of traditional medicines in diabetics mellitus, Diabetics Care, 13

10.1078/0944-7113-00009

Waheed A., 2006, Clinical investigation of hypoglycemic effect of leaves of Mangifera indica in type-2 (NIDDM) diabetes mellitus, Pakistan Journal of Pharmacology, 23, 13

10.1076/phbi.35.2.130.13276

Wadood N., 2000, Effect of Mangifera indica on blood glucose and total lipid levels of normal and alloxan diabetic rabbits, Pakistan Journal of Medical Research, 39, 142

10.3329/bjp.v4i2.2488

10.1016/S0140-6736(84)91816-6

10.1016/j.mpsur.2011.08.006

10.1016/j.jep.2005.11.032

10.3390/molecules14031098

Neelima N., 2017, Anti-ulcer activity and HPTLC analysis of Mangifera indica L. leaves, International Journal of Pharmaceutical and Phytopharmacological Research, 1, 146

Akindele A. J., 2012, Gastroprotective effects of DAS-77 (a Phytomedicine) in ulcer models in rats, Tropical Journal of Pharmaceutical Research, 11, 783

Nethravathi K., 2015, Evaluation of antiulcer activity of Mangifera indica kernel, vitamins and zinc sulphate on pylorus ligation and ethanol induced ulcer models in rats, International Journal of Phytopharmacology, 6, 86