A Review of Repurposed Cancer Drugs in Clinical Trials for Potential Treatment of COVID-19
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Zheng, 2020, SARS-CoV-2: An Emerging Coronavirus that Causes a Global Threat, Int J Biol Sci., 16, 1678, 10.7150/ijbs.45053
Drinka, 2003, Influenza vaccination and antiviral therapy: Is there a role for concurrent administration in the institutionalised elderly?, Drugs Aging, 20, 165, 10.2165/00002512-200320030-00001
Deb, P., Molla, M.A., and Saif-Ur-Rahman, K. (2021). An update to monoclonal antibody as therapeutic option against COVID-19. Biosaf. Health.
Pushpakom, 2019, Drug repurposing: Progress, challenges and recommendations, Nat. Rev. Drug Discov., 18, 41, 10.1038/nrd.2018.168
Hernandez, 2017, Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics, Front Oncol., 7, 273, 10.3389/fonc.2017.00273
Sultana, 2020, Challenges for drug repurposing in the COVID-19 pandemic era, Front. Pharmacol., 11, 1657, 10.3389/fphar.2020.588654
Parvathaneni, 2020, Utilizing drug repurposing against COVID-19—Efficacy, limitations, and challenges, Life Sci., 259, 118275, 10.1016/j.lfs.2020.118275
Saini, 2020, Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy, Br. J. Cancer, 123, 694, 10.1038/s41416-020-0948-x
(2021, February 06). National Center for Advancing Translational Sciences|OpenData Portal, Available online: https://opendata.ncats.nih.gov/covid19/databrowser.
(2021, February 06). ClinicalTrials.gov, Available online: https://www.clinicaltrials.gov/ct2/home.
(2021, February 06). European Pharmaceutical Review|News. Available online: https://www.europeanpharmaceuticalreview.com/.
Fehr, 2015, Coronaviruses: An overview of their replication and pathogenesis, Methods Mol. Biol., 1282, 1, 10.1007/978-1-4939-2438-7_1
Astuti, 2020, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response, Diabetes Metab. Syndr., 14, 407, 10.1016/j.dsx.2020.04.020
Romano, M., Ruggiero, A., Squeglia, F., Maga, G., and Berisio, R.A. (2020). Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping. Cells, 9.
Zingaropoli, 2021, Major reduction of NKT cells in patients with severe COVID-19 pneumonia, Clin. Immunol., 222, 108630, 10.1016/j.clim.2020.108630
Jin, 2020, Endothelial activation and dysfunction in COVID-19: From basic mechanisms to potential therapeutic approaches, Signal. Transduct. Target. Ther., 5, 1
Boechat, J.L., Chora, I., Morais, A., and Delgado, L. (2021). The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives. Pulmonology.
Minn, 2015, Interferons and the immunogenic effects of cancer therapy, Trends Immunol., 36, 725, 10.1016/j.it.2015.09.007
Lin, 2014, Interferons: Success in anti-viral immunotherapy, Cytokine Growth Factor Rev., 25, 369, 10.1016/j.cytogfr.2014.07.015
Hung, 2020, Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: An open-label, randomised, phase 2 trial, Lancet, 395, 1695, 10.1016/S0140-6736(20)31042-4
Abdolvahab, 2021, Potential role of interferons in treating COVID-19 patients, Int. Immunopharmacol., 90, 107171, 10.1016/j.intimp.2020.107171
Ruiz, 2020, SARS-CoV-2 infection: The role of cytokines in COVID-19 disease, Cytokine Growth Factor Rev., 54, 62, 10.1016/j.cytogfr.2020.06.001
Lacroix, 2020, Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex, J. Biol. Chem., 290, 26943, 10.1074/jbc.M115.682138
Khan, F.A., Stewart, I., Fabbri, L., Moss, S., Robinson, K., Smyth, A.R., and Jenkins, G. (2021). Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19. Thorax.
Sullivan, R.J., Johnson, D.B., Rini, B., Neilan, T.G., Lovly, C.M., Moslehi, J.J., and Reynolds, K.L. (2020). COVID-19 and immune checkpoint inhibitors: Initial considerations. J. Immunother. Cancer, 8.
Chen, 2020, T cell responses in patients with COVID-19, Nat. Rev. Immunol., 20, 529, 10.1038/s41577-020-0402-6
Saito, N., Yoshida, K., Okamoto, M., Sasaki, J., Kuroda, C., Ishida, H., Ueda, K., Ideta, H., Kamanaka, T., and Sobajima, A. (2019). Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells. BMC Cancer, 20.
Mollica, 2020, The pivotal role of TMPRSS2 in coronavirus disease 2019 and prostate cancer, Future Oncol., 16, 2029, 10.2217/fon-2020-0571
Chakravarty, 2020, Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer, Commun. Biol., 3, 1, 10.1038/s42003-020-1088-9
Martin, 2020, Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2, J. Proteome Res., 19, 4670, 10.1021/acs.jproteome.0c00397
Cheng, F., Rao, S., and Mehra, R. (2020). COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach. Cleve Clin. J. Med.
White, K.M., Rosales, R., Yildiz, S., Kehrer, T., Miorin, L., Moreno, E., Jangra, S., Uccellini, M.B., Rathnasinghe, R., and Coughlan, L. (2021). Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science, 926–931.
Nebigil, 2020, Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses, Eur. J. Med. Chem., 203, 112653, 10.1016/j.ejmech.2020.112653
Sriskantharajah, 2013, Targeting phosphoinositide 3-kinase δ for the treatment of respiratory diseases, Ann. N. Y. Acad. Sci., 1280, 35, 10.1111/nyas.12039
Murdaca, 2020, Vitamin D and Covid-19: An update on evidence and potential therapeutic implications, Clin. Mol. Allergy, 18, 1, 10.1186/s12948-020-00139-0
Gordon, 2020, A SARS-CoV-2 protein interaction map reveals targets for drug repurposing, Nature, 583, 459, 10.1038/s41586-020-2286-9
(2020, January 03). Repurposed Drugs with Broad-Spectrum Antiviral Activity, by BioRender.com. Available online: https://app.biorender.com/biorender-templates.