A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions
Tóm tắt
Từ khóa
Tài liệu tham khảo
Kessler, 2005, Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication, Arch. Gen. Psychiatry, 62, 593, 10.1001/archpsyc.62.6.593
Kessler, 2005, Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication, Arch. Gen. Psychiatry, 62, 617, 10.1001/archpsyc.62.6.617
American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5, American Psychiatric Association. [5th ed.].
National Center for Post-Traumatic Stress Disorder (2008). PTSD Research Quarterly.
Kulis, 2015, Whole-genome fingerprint of the DNA methylome during human B cell differentiation, Nat. Genet., 47, 746, 10.1038/ng.3291
Graff, 2014, Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories, Cell, 156, 261, 10.1016/j.cell.2013.12.020
Knox, 2012, Glucocorticoid receptors and extinction retention deficits in the single prolonged stress model, Neuroscience, 223, 163, 10.1016/j.neuroscience.2012.07.047
Pape, 2014, Psychological trauma as risk for delayed psychiatric disorders: epigenetic mechanisms, Nervenarzt, 85, 1382, 10.1007/s00115-014-4085-8
Akbarian, 2014, Chapter two—Epigenetics in posttraumatic stress disorder, Progress in Molecular Biology and Translational Science, Volume 128, 29, 10.1016/B978-0-12-800977-2.00002-4
Sheerin, 2017, The genetics and epigenetics of PTSD: Overview, recent advances, and future directions, Curr. Opin. Psychol., 14, 5, 10.1016/j.copsyc.2016.09.003
Bachmann, 2005, Glucocorticoid receptor polymorphisms and post-traumatic stress disorder, Psychoneuroendocrinology, 30, 297, 10.1016/j.psyneuen.2004.08.006
Bryant, 2010, Preliminary evidence of the short allele of the serotonin transporter gene predicting poor response to cognitive behavior therapy in posttraumatic stress disorder, Biol. Psychiatry, 67, 1217, 10.1016/j.biopsych.2010.03.016
Comings, 1996, Dopamine D2 receptor (DRD2) gene and susceptibility to posttraumatic stress disorder: a study and replication, Biol. Psychiatry, 40, 368, 10.1016/0006-3223(95)00519-6
Kilpatrick, 2007, The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults, Am. J. Psychiatry, 164, 1693, 10.1176/appi.ajp.2007.06122007
Stein, 2016, Genome-wide association studies of posttraumatic stress disorder in 2 cohorts of us army soldiers, JAMA Psychiatry, 73, 695, 10.1001/jamapsychiatry.2016.0350
Garrett, 2015, Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq–Afghanistan era veterans, J. Affect. Disord., 184, 225, 10.1016/j.jad.2015.03.049
Mehta, 2017, Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD, Acta Psychiatr. Scand., 136, 493, 10.1111/acps.12778
Binder, 2008, Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults, JAMA, 299, 1291, 10.1001/jama.299.11.1291
Chen, 2016, Expression and methylation in posttraumatic stress disorder and resilience; evidence of a role for odorant receptors, Psychiatry Res., 245, 36, 10.1016/j.psychres.2016.07.045
Maddox, 2018, Estrogen-dependent association of HDAC4 with fear in female mice and women with PTSD, Mol. Psychiatry, 23, 658, 10.1038/mp.2016.250
Uddin, 2010, Epigenetic and immune function profiles associated with posttraumatic stress disorder, Proc. Natl. Acad. Sci. USA, 107, 9470, 10.1073/pnas.0910794107
Almli, 2014, Genetic approaches to understanding post-traumatic stress disorder, Int. J. Neuropsychopharmacol., 17, 355, 10.1017/S1461145713001090
Daskalakis, 2018, Recent genetics and epigenetics approaches to PTSD, Curr. Psychiatry Rep., 20, 30, 10.1007/s11920-018-0898-7
Rady, 2010, Psychogenetics of post-traumatic stress disorder: A short review, Appl. Clin. Genet., 3, 103, 10.2147/TACG.S13926
Wolf, 2014, A Genome-Wide Association study of clinical symptoms of dissociation in a trauma-exposed sample, Depress. Anxiety, 31, 352, 10.1002/da.22260
Ressler, 2011, Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor, Nature, 470, 492, 10.1038/nature09856
Lu, 2008, Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder, Am. J Med. Genet. B. Neuropsychiatr. Genet., 147B, 1488, 10.1002/ajmg.b.30693
Chang, S.-C., Koenen, K.C., Galea, S., Aiello, A.E., Soliven, R., Wildman, D.E., and Uddin, M. (2012). Molecular variation at the SLC6A3 locus predicts lifetime risk of PTSD in the Detroit neighborhood health study. PLOS ONE, 7.
Gelernter, 1999, No association between D2 dopamine receptor (DRD2) "A" system alleles, or DRD2 haplotypes, and posttraumatic stress disorder, Biol. Psychiatry, 45, 620, 10.1016/S0006-3223(98)00087-0
Klengel, 2013, Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions, Nat. Neurosci., 16, 33, 10.1038/nn.3275
Duncan, 2018, Largest GWAS of PTSD (N = 20,070) yields genetic overlap with schizophrenia and sex differences in heritability, Mol. Psychiatr., 23, 666, 10.1038/mp.2017.77
Wilhelmsen, 2017, Genome-wide association study of post-traumatic stress disorder in two high-risk populations, Twin Res. Hum. Genet., 20, 197, 10.1017/thg.2017.12
Nievergelt, 2015, Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene, Psychoneuroendocrinology, 51, 459, 10.1016/j.psyneuen.2014.10.017
Logue, 2012, A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus, Mol. Psychiatry, 18, 937, 10.1038/mp.2012.113
Sadeh, 2016, Epigenetic variation at SKA2 predicts suicide phenotypes and internalizing psychopathology, Depress. Anxiety, 33, 308, 10.1002/da.22480
Kaminsky, 2015, Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder, Transl. Psychiatry, 5, e627, 10.1038/tp.2015.105
Xie, 2013, Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder, Biol. Psychiatry, 74, 656, 10.1016/j.biopsych.2013.04.013
Uddin, 2011, Gene expression and methylation signatures of MAN2C1 are associated with PTSD, Dis Markers, 30, 111, 10.1155/2011/513659
Paciotti, 2014, Accumulation of free oligosaccharides and tissue damage in cytosolic α-mannosidase (Man2c1)-deficient mice, J. Biol. Chem., 289, 9611, 10.1074/jbc.M114.550509
Hosokawa, 2001, A novel ER α-mannosidase-like protein accelerates ER-associated degradation, EMBO Rep., 5, 415, 10.1093/embo-reports/kve084
Han, 2013, Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder, PLoS ONE, 8, e69340, 10.1371/journal.pone.0069340
Smith, 2011, Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder, Am. J. Med. Genet. B. Neuropsychiatr. Genet., 156, 700, 10.1002/ajmg.b.31212
Siddiqui, 2017, Enhanced histone acetylation in the infralimbic prefrontal cortex is associated with fear extinction, Cell. Mol. Neurobiol., 37, 1287, 10.1007/s10571-017-0464-6
Singh, 2018, Decreased level of histone acetylation in the infralimbic prefrontal cortex following immediate extinction may result in deficit of extinction memory, Brain Res. Bull., 140, 355, 10.1016/j.brainresbull.2018.06.004
Bam, 2016, Evidence for epigenetic regulation of pro-inflammatory cytokines, interleukin-12 and interferon γ, in peripheral blood mononuclear cells from PTSD patients, J Neuroimmune Pharmacol., 11, 168, 10.1007/s11481-015-9643-8
Schmidt, 2013, Therapeutic action of fluoxetine is associated with a reduction in prefrontal cortical miR-1971 expression levels in a mouse model of posttraumatic stress disorder, Front. Psychiatr., 4, 66, 10.3389/fpsyt.2013.00066
Felitti, 1998, Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study, Am. J. Prev. Med., 14, 245, 10.1016/S0749-3797(98)00017-8
Brockie, 2015, The Relationship of Adverse Childhood Experiences to PTSD, depression, poly-drug use and suicide attempt in reservation-based native American adolescents and young adults, Am. J. Community Psychol., 55, 411, 10.1007/s10464-015-9721-3
LeardMann, C.A., Smith, B., and Ryan, M.A. (2010). Do adverse childhood experiences increase the risk of postdeployment posttraumatic stress disorder in US Marines?. BMC Public Health, 10.
Mersky, 2018, Poor mental health among low-income women in the U.S.: The roles of adverse childhood and adult experiences, Soc. Sci. Med., 206, 14, 10.1016/j.socscimed.2018.03.043
Yehuda, 2010, Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD, Psychopharmacology (Berl), 212, 405, 10.1007/s00213-010-1969-6
Weder, 2014, Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry, J. Am. Acad. Child Adolesc. Psychiatry, 53, 417, 10.1016/j.jaac.2013.12.025
Moser, D.A., Paoloni-Giacobino, A., Stenz, L., Adouan, W., Manini, A., Suardi, F., Cordero, M.I., Vital, M., Sancho Rossignol, A., and Rusconi-Serpa, S. (2015). BDNF methylation and maternal brain activity in a violence-related sample. PLoS ONE, 10.
Perroud, 2014, The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis, World J. Biol. Psychiatry, 15, 334, 10.3109/15622975.2013.866693
Watkeys, 2018, Glucocorticoid receptor gene (NR3C1) DNA methylation in association with trauma, psychopathology, transcript expression, or genotypic variation: A systematic review, Neurosci. Biobehav. Rev., 95, 85, 10.1016/j.neubiorev.2018.08.017
Yehuda, 2016, Holocaust exposure induced intergenerational effects on FKBP5 methylation, Biol. Psychiatry, 80, 372, 10.1016/j.biopsych.2015.08.005
Lee, 2010, Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice, Endocrinology, 151, 4332, 10.1210/en.2010-0225
Yang, 2012, Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5, Biochem. Biophys. Res. Commun., 420, 570, 10.1016/j.bbrc.2012.03.035
Yehuda, 2013, Epigenetic biomarkers as predictors and correlates of symptom improvement following psychotherapy in combat veterans with PTSD, Front. Psychiatry, 4, 118, 10.3389/fpsyt.2013.00118
Kuan, 2017, An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders, Transl. Psychiatry, 7, e1158, 10.1038/tp.2017.130
Olsson, 2010, Prospects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depression, Biol. Psychol., 83, 159, 10.1016/j.biopsycho.2009.12.003
Homberg, 2018, Modulation of glucocorticoids by the serotonin transporter polymorphism: A narrative review, Neurosci. Biobehav. Rev., 92, 338, 10.1016/j.neubiorev.2018.06.022
Fuchikami, M., Morinobu, S., Segawa, M., Okamoto, Y., Yamawaki, S., Ozaki, N., Inoue, T., Kusumi, I., Koyama, T., and Tsuchiyama, K. (2011). DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS ONE, 6.
Roth, 2011, Epigenetic modification of hippocampal BDNF DNA in adult rats in an animal model of post-traumatic stress disorder, J. Psychiatr. Res., 45, 919, 10.1016/j.jpsychires.2011.01.013
Solanki, 2015, Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder, Nutr. Res., 35, 65, 10.1016/j.nutres.2014.11.008
Sawamura, 2016, Dexamethasone treatment leads to enhanced fear extinction and dynamic Fkbp5 regulation in amygdala, Neuropsychopharmacology, 41, 832, 10.1038/npp.2015.210
Papadopoulos, 2011, GABAergic control of novelty stress-responsive epigenetic and gene expression mechanisms in the rat dentate gyrus, Neuropsychopharmacology, 21, 316, 10.1016/j.euroneuro.2010.05.005
Sillivan, 2015, Neuroepigenetic regulation of pathogenic memories, Neuroepigenetics, 1, 28, 10.1016/j.nepig.2014.10.003
Levenson, 2004, Regulation of histone acetylation during memory formation in the hippocampus, J. Biol. Chem., 279, 40545, 10.1074/jbc.M402229200
Wang, 2010, The extinction of morphine-induced conditioned place preference by histone deacetylase inhibition, Neurosci. Lett., 483, 137, 10.1016/j.neulet.2010.07.080
Krzyzewska, 2018, Genetic variant in CACNA1C is associated with PTSD in traumatized police officers, Eur. J. Hum. Genet., 26, 247, 10.1038/s41431-017-0059-1
Pizzimenti, 2015, Epigenetics and memory: causes, consequences and treatments for post-traumatic stress disorder and addiction, Genes Brain Behav., 14, 73, 10.1111/gbb.12187
Sartor, 2011, Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women, Psychol. Med., 41, 1497, 10.1017/S0033291710002072
Inserra, 2018, Hypothesis: The psychedelic ayahuasca heals traumatic memories via a σ 1 receptor-mediated epigenetic-mnemonic process, Front. Pharmacol., 9, 330, 10.3389/fphar.2018.00330
Tsai, 2015, Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope, Proc. Natl. Acad. Sci. USA, 112, 6562, 10.1073/pnas.1518894112
Labonte, 2012, Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse, Biol. Psychiatry, 72, 41, 10.1016/j.biopsych.2012.01.034
Labonte, 2014, Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder, Transl. Psychiatry, 4, e368, 10.1038/tp.2014.3
Ferdosi, H., Schwab, K.A., Metti, A., Brenner, L.A., Terrio, H., Pazdan, R.M., Cole, W.R., and Scher, A.I. (2018). Trajectory of postconcussive symptoms 12-months post-deployment in soldiers with and without mild traumatic brain injury—Warrior STRONG Study. Am. J. Epidemiol.
Nevarez, 2017, Friendship in war: Camaraderie and prevention of posttraumatic stress disorder prevention, J. Trauma. Stress, 30, 512, 10.1002/jts.22224
Albanese, B.J., Macatee, R.J., Stentz, L.A., Schmidt, N.B., and Bryan, C.J. (2018). Interactive effects of cumulative lifetime traumatic brain injuries and combat exposure on posttraumatic stress among deployed military personnel. Cogn. Behav. Ther., 1–12.
Wolf, 2018, Accelerated DNA methylation age: Associations with posttraumatic stress disorder and mortality, Psychosom. Med., 80, 42, 10.1097/PSY.0000000000000506