Một Vai Trò Có Thể Có Của Di truyền Nền Trong Các Bệnh Xương Phụ Thuộc Tuổi

Waddington C. The epigenotype. Endeavour. 1942;1:18–20. Feinberg AP. Epigenetics at the epicenter of modern medicine. Jama. 2008;299:1345–50. Feinberg AP. A genetic approach to cancer epigenetics. Cold Spring Harb Symp Quant Biol. 2005;70:335–41. Graff J, Mansuy IM. Epigenetic dysregulation in cognitive disorders. Eur J Neurosci. 2009;30:1–8. Brooks WH, Le Dantec C, Pers JO, Youinou P, Renaudineau Y. Epigenetics and autoimmunity. J Autoimmunity. 2010;34(3):J207–19. Calvanese V, Lara E, Kahn A, Fraga MF. The role of epigenetics in aging and age-related diseases. Ageing Res Rev. 2009;8:268–76. Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature. 1997;389:251–60. Kouzarides T. Chromatin modifications and their function. Cell. 2007;128:693–705. Berger SL. The complex language of chromatin regulation during transcription. Nature. 2007;447:407–12. Wang Y, Leung FC. An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics. 2004;20:1170–7. Ehrlich M, Gama-Sosa MA, Huang LH, et al. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 1982;10:2709–21. Kim JK, Samaranayake M, Pradhan S. Epigenetic mechanisms in mammals. Cell Mol Life Sci. 2009;66:596–612. Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science. 2001;293:1089–93. Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci. 2006;31:89–97. Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature. 2007;449:248–51. Bird AP, Wolffe AP. Methylation-induced repression—belts, braces, and chromatin. Cell. 1999;99:451–4. Strahl BD, Allis CD. The language of covalent histone modifications. Nature. 2000;403:41–5. Costa FF. Non-coding RNAs, epigenetics and complexity. Gene. 2008;410:9–17. Ambros V, Chen X. The regulation of genes and genomes by small RNAs. Development. 2007;134:1635–41. Ng K, Pullirsch D, Leeb M, Wutz A. Xist and the order of silencing. EMBO Rep. 2007;8:34–9. Weinert BT, Timiras PS. Invited review: theories of aging. J Appl Physiol. 2003;95:1706–16. Fraga MF. Genetic and epigenetic regulation of aging. Curr Opin Immunol. 2009;21:446–53. Bennett-Baker PE, Wilkowski J, Burke DT. Age-associated activation of epigenetically repressed genes in the mouse. Genetics. 2003;165:2055–62. Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA. 2005;102:10604–9. Poulsen P, Esteller M, Vaag A, Fraga MF. The epigenetic basis of twin discordance in age-related diseases. Pediatr Res. 2007;61:38R–42R. Bjornsson HT, Sigurdsson MI, Fallin MD, et al. Intra-individual change over time in DNA methylation with familial clustering. Jama. 2008;299:2877–83. Vogt G, Huber M, Thiemann M, van den Boogaart G, Schmitz OJ, Schubart CD. Production of different phenotypes from the same genotype in the same environment by developmental variation. J Exp Biol. 2008;211:510–23. Wong AH, Gottesman II, Petronis A. Phenotypic differences in genetically identical organisms: the epigenetic perspective. Hum Mol Genet. 2005;14(Spec No 1):R11–8. Cropley JE, Suter CM, Beckman KB, Martin DI. Germ-line epigenetic modification of the murine A vy allele by nutritional supplementation. Proc Natl Acad Sci USA. 2006;103:17308–12. Weaver IC, Champagne FA, Brown SE, et al. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci. 2005;25:11045–54. Bjornsson HT, Fallin MD, Feinberg AP. An integrated epigenetic and genetic approach to common human disease. Trends Genet. 2004;20:350–8. Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. 2003;23:5293–300. Holliday R. The inheritance of epigenetic defects. Science. 1987;238:163–70. (New York, NY). Poulsen P, Kyvik KO, Vaag A, Beck-Nielsen H. Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance—a population-based twin study. Diabetologia. 1999;42:139–45. Williams FM, Spector TD. Recent advances in the genetics of osteoporosis. J Musculoskelet Neuronal Interact. 2006;6:27–35. Chesnut CH III. Theoretical overview: bone development, peak bone mass, bone loss, and fracture risk. Am J Med. 1991;91:2S–4S. Ralston SH. Genetics of osteoporosis. Proc Nutr Soc. 2007;66:158–65. Kannus P, Palvanen M, Kaprio J, Parkkari J, Koskenvuo M. Genetic factors and osteoporotic fractures in elderly people: prospective 25 year follow up of a nationwide cohort of elderly Finnish twins. BMJ. 1999;319:1334–7. (Clinical research ed). Michaelsson K, Melhus H, Ferm H, Ahlbom A, Pedersen NL. Genetic liability to fractures in the elderly. Arch Intern Med. 2005;165:1825–30. Lipsky PE. Why does rheumatoid arthritis involve the joints? N Engl J Med. 2007;356:2419–20. Grabiec AM, Tak PP, Reedquist KA. Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? Arthritis Res Ther. 2008;10:226. Li E, Bird A. DNA methylation in mammals. In: Allis CD, Jenuwein T, Reinberg D, editors; Marie-Laure Caparros. New York: Cold Spring Harbor Laboratory Press; 2007. p. 341–357. Cashen AF, Schiller GJ, O’Donnell MR, Dipersio JF. Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. J Clin Oncol. 2010;28:556–61. Patel R, Shervington L, Lea R, Shervington A. Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. Brain Res. 2008;1188:173–81.