A Pheromone Influences Larval Development in the Nematode Caenorhabditis elegans

American Association for the Advancement of Science (AAAS) - Tập 218 Số 4572 - Trang 578-580 - 1982
James W. Golden1, Donald L Riddle1
1Division of Biological Sciences, University of Missouri, Columbia 65211.

Tóm tắt

A Caenorhabditis -specific pheromone and the food supply influence both entry into and exit from a developmentally arrested juvenile stage called the dauer larva. The pheromone increases the frequency of dauer larva formation and inhibits recovery but does not affect adult behavior such as chemotaxis and egg laying. The fatty acid-like pheromone has been partially purified and characterized by a new bioassay. If similar developmental control mechanisms are used by parasitic nematodes, such mechanisms might be exploited to develop highly selective anthelmintic agents.

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Tài liệu tham khảo

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American Association for the Advancement of Science (AAAS)

Tập 218 Số 4572

578-580

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