A Map of Recent Positive Selection in the Human Genome
Tóm tắt
Từ khóa
Tài liệu tham khảo
2002, Evolution, consequences and future of plant and animal domestication., Nature, 418, 700, 10.1038/nature01019
2004, Human evolutionary genetics: Origins, peoples and disease
2001, Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance., Science, 293, 455, 10.1126/science.1061573
2002, Complex signatures of natural selection at the Duffy blood group locus., Am J Hum Genet, 70, 369, 10.1086/338628
2002, Detecting recent positive selection in the human genome from haplotype structure., Nature, 419, 832, 10.1038/nature01140
2004, Genetic signatures of strong recent positive selection at the lactase gene., Am J Hum Genet, 74, 1111, 10.1086/421051
2004, CYP3A variation and the evolution of salt-sensitivity variants., Am J Hum Genet, 75, 1059, 10.1086/426406
2005, Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans., Science, 309, 1717, 10.1126/science.1113722
2005, Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens., Science, 309, 1720, 10.1126/science.1116815
2003, Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios., Science, 302, 1960, 10.1126/science.1088821
2005, A scan for positively selected genes in the genomes of humans and chimpanzees., PLoS Biol, 3, e170, 10.1371/journal.pbio.0030170
Chimpanzee Sequencing and Analysis Consortium, 2005, Initial sequence of the chimpanzee genome and comparison with the human genome., Nature, 437, 69, 10.1038/nature04072
2003, A genome scan to detect candidate regions influenced by local natural selection in human populations., Mol Biol Evol, 20, 893, 10.1093/molbev/msg092
2004, Population history and natural selection shape patterns of genetic variation in 132 genes., PLoS Biol, 2, e286, 10.1371/journal.pbio.0020286
2004, Genome scans of DNA variability in humans reveal evidence for selective sweeps outside of Africa., Mol Biol Evol, 21, 1800, 10.1093/molbev/msh192
2005, Disentangling the effects of demography and selection in human history., Mol Biol Evol, 22, 63
2005, Genomic regions exhibiting positive selection identified from dense genotype data., Genome Res, 15, 1553, 10.1101/gr.4326505
The International HapMap Consortium, 2005, A haplotype map of the human genome., Nature, 437, 1299, 10.1038/nature04226
1962, Diabetes mellitus: A “thrifty” genotype rendered detrimental by “progress”?, Am J Hum Genet, 14, 353
2005, An evolutionary framework for common diseases: the ancestral-susceptibility model., Trends Genet, 21, 596, 10.1016/j.tig.2005.08.007
2005, Population genetics of CAPN10 and GPR35: Implications for the evolution of type 2 diabetes variants., Am J Hum Genet, 76, 548, 10.1086/428784
2005, Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation., Am J Hum Genet, 76, 449, 10.1086/428594
2003, Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data., Genetics, 165, 2213, 10.1093/genetics/165.4.2213
1994, Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster., Genetics, 136, 1329, 10.1093/genetics/136.4.1329
1995, Haplotype test reveals departure from neutrality in a segment of the white gene of Drosophila melanogaster., Genetics, 141, 1483, 10.1093/genetics/141.4.1483
1999, Unusual haplotype structure at the proximal breakpoint of In(2L)t in a natural population of Drosophila melanogaster., Genetics, 153, 1297, 10.1093/genetics/153.3.1297
2001, The use of intraallelic variability for testing neutrality and estimating population growth rate., Genetics, 158, 865, 10.1093/genetics/158.2.865
2002, Sequence variation and haplotype structure at the human HFE locus., Genetics, 161, 1609, 10.1093/genetics/161.4.1609
2004, The fine-scale structure of recombination rate variation in the human genome., Science, 304, 581, 10.1126/science.1092500
2004, Evidence for substantial fine-scale variation in recombination rates across the human genome., Nat Genet, 36, 700, 10.1038/ng1376
2005, A fine-scale map of recombination rates and hotspots across the human genome., Science, 310, 321, 10.1126/science.1117196
2005, Microsatellite variation and evolution of human lactase persistence., Hum Genet, 117, 329, 10.1007/s00439-005-1322-z
2002, Inferences about human demography based on multilocus analyses of noncoding sequences., Genetics, 161, 1209, 10.1093/genetics/161.3.1209
2005, Interrogating multiple aspects of variation in a full re-sequencing data set to infer human population size changes., PNAS, 102, 18508, 10.1073/pnas.0507325102
2000, Hitchhiking under positive Darwinian selection., Genetics, 155, 1405, 10.1093/genetics/155.3.1405
2002, A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity., Am J Hum Genet, 71, 84, 10.1086/341290
2003, Natural selection on the olfactory receptor gene family in humans and chimpanzees., Am J Hum Genet, 73, 489, 10.1086/378132
1974, The hitch-hiking effect of a favourable gene., Genet Res Camb, 23, 23, 10.1017/S0016672300014634
2003, PANTHER: A browsable database of gene products organized by biological function, using curated protein family and subfamily classification., Nucleic Acids Res, 31, 334, 10.1093/nar/gkg115
OMIM, 2000, Online Mendelian Inheritance in Man. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information
2005, Entrez Gene: Gene-centered information at NCBI., Nucleic Acids Res, 33, 54
2005, Pervasive adaptive evolution in primate seminal proteins., PLoS Genet, 1, e35, 10.1371/journal.pgen.0010035
2005, SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans., Science, 310, 1782, 10.1126/science.1116238
2005, A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size., Nat Genet, 37, 353, 10.1038/ng1539
1999, Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism., Am J Hum Genet, 65, 795, 10.1086/302540
2002, Generating samples under a Wright-Fisher neutral model of genetic variation., Bioinformatics, 18, 337, 10.1093/bioinformatics/18.2.337
2004, SelSim: A program to simulate population genetic data with natural selection and recombination., Bioinformatics, 20, 3673, 10.1093/bioinformatics/bth417
2004, Maximum-likelihood estimation of demographic parameters using the frequency spectrum of unlinked single-nucleotide polymorphisms., Genetics, 168, 1699, 10.1534/genetics.104.030171
2004, The allele frequency spectrum in genome-wide human variation data reveals signals of differential demographic history in three large world populations., Genetics, 166, 351, 10.1534/genetics.166.1.351
2004, Population genetic analysis of ascertained SNP data., Hum Genomics, 1, 218, 10.1186/1479-7364-1-3-218
2006, A fast and flexible statistical model for large-scale population genotype data: Applications to inferring missing genotypes and haplotypic phase., Am J Hum Genet