Vitamin D deficiency: a worldwide problem with health consequences

Holick, 1989, Phylogenetic and evolutionary aspects of vitamin D from phytoplankton to humans., 7 Holick, 2003, Vitamin D: A millennium perspective., J Cell Biochem, 88, 296, 10.1002/jcb.10338 Sniadecki, 1939, Jerdrzej Sniadecki (1768–1838) on the cure of rickets. (1840) Cited by W Mozolowski., Nature, 143, 121, 10.1038/143121a0 Holick, 2006, Resurrection of vitamin D deficiency and rickets., J Clin Invest, 116, 2062, 10.1172/JCI29449 Hess, 1936, 669 Hess, 1921, The cure of infantile rickets by sunlight., JAMA, 77, 39, 10.1001/jama.1921.02630270037013 1964, Infantile hypercalcaemia, nutritional rickets, and infantile scurvy in Great Britain., Br Med J, 1, 1659, 10.1136/bmj.1.5399.1659 Brot, 2001, Vitamin D status and its adequacy in healthy Danish perimenopausal women: relationships to dietary intake, sun exposure and serum parathyroid hormone., Br J Nutr, 86, S97, 10.1079/BJN2001345 Chen, 2007, Factors that influence the cutaneous synthesis and dietary sources of vitamin D., Arch Biochem Biophys, 460, 213, 10.1016/j.abb.2006.12.017 Holick, 2007, Vitamin D deficiency., N Engl J Med, 357, 266, 10.1056/NEJMra070553 Chapuy, 1996, Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter., J Clin Endocrinol Metab, 81, 1129 Dawson-Hughes, 2005, Estimates of optimal vitamin D status., Osteoporos Int, 16, 713, 10.1007/s00198-005-1867-7 Malabanan, 1998, Redefining vitamin D insufficiency., Lancet, 351, 805, 10.1016/S0140-6736(05)78933-9 Holick, 2005, Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy., J Clin Endocrinol Metab, 90, 3215, 10.1210/jc.2004-2364 Thomas, 1998, Hypovitaminosis D in medical inpatients., N Engl J Med, 338, 777, 10.1056/NEJM199803193381201 Heaney, 2003, Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D., J Am Coll Nutr, 22, 142, 10.1080/07315724.2003.10719287 Vieth, 1999, Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety., Am J Clin Nutr, 69, 842, 10.1093/ajcn/69.5.842 Huldschinsky, 1919, Heilung von Rachitis durch Kunstliche Hohensonne., Ultraviolet irradiation of rachitic children.) Deutsche Med Wochenschr, 45, 712, 10.1055/s-0028-1137830 Bakhtiyarova, 2006, Vitamin D status among patients with hip fracture and elderly control subjects in Yekaterinburg, Russia., Osteoporos Int, 17, 441, 10.1007/s00198-005-0006-9 Larsen, 2004, Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: a pragmatic population-based 3-year intervention study., J Bone Miner Res, 19, 370, 10.1359/JBMR.0301240 Simpson, 1985, Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle., J Biol Chem, 260, 8882, 10.1016/S0021-9258(17)39433-4 Bischoff-Ferrari, 2004, Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged ≥60 y., Am J Clin Nutr, 80, 752, 10.1093/ajcn/80.3.752 Broe, 2007, A higher dose of vitamin D reduces the risk of falls in nursing home residents: a randomized, multiple-dose study., J Am Geriatr Soc, 55, 234, 10.1111/j.1532-5415.2007.01048.x Visser, 2003, Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength an muscle mass (sarcopenia): the longitudinal aging study Amsterdam., J Clin Endocrinol Metab, 88, 5766, 10.1210/jc.2003-030604 Malabanan, 1998, Severe generalized bone pain and osteoporosis in a premenopausal black female: effect of vitamin D replacement., J Clin Densitom, 1, 201, 10.1385/JCD:1:2:201 Aaron, 1974, Frequency of osteomalacia and osteoporosis in fractures of the proximal femur., Lancet, 1, 229, 10.1016/S0140-6736(74)92545-8 Al-Ali, 2000, Nutritional osteomalacia: substantial clinical improvement and gain in bone density post therapy., J Clin Densitom, 3, 97, 10.1385/JCD:3:1:097 Plotnikoff, 2003, Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain., Mayo Clin Proc, 78, 1463, 10.4065/78.12.1463 Clemens, 1982, Increased skin pigment reduces the capacity of skin to synthesise vitamin D3., Lancet, 74, 10.1016/S0140-6736(82)90214-8 Matsuoka, 1987, Sunscreens suppress cutaneous vitamin D3 synthesis., J Clin Endocrinol Metab, 64, 1165, 10.1210/jcem-64-6-1165 Webb, 1988, Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin., J Clin Endocrinol Metab, 67, 373, 10.1210/jcem-67-2-373 Thacher, 2006, Nutritional rickets around the world: causes and future directions., Ann Trop Paediatr, 26, 1, 10.1179/146532806X90556 Sedrani, 1984, Low 25-hydroxyvitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region., Ann Nutr Metab, 28, 181, 10.1159/000176801 Fuleihan, 2001, Hypovitaminosis D in healthy schoolchildrren., Pediatrics, 107, 53, 10.1542/peds.107.4.e53 Tangpricha, 2002, Vitamin D insufficiency among free-living healthy young adults., Am J Med, 112, 659, 10.1016/S0002-9343(02)01091-4 Gordon, 2004, Prevalence of vitamin D deficiency among healthy adolescents., Arch Pediatr Adolesc Med, 158, 531, 10.1001/archpedi.158.6.531 Sullivan, 2005, Adolescent girls in Maine at risk for vitamin D insufficiency., J Am Diet Assoc, 105, 971, 10.1016/j.jada.2005.03.002 Lips, 2001, A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial., J Clin Endocrinol Metab, 86, 1212, 10.1210/jcem.86.3.7327 Marwaha, 2005, Vitamin D and bone mineral density status of healthy schoolchildren in northern India., Am J Clin Nutr, 82, 477, 10.1093/ajcn/82.2.477 McGrath, 2001, Vitamin D insufficiency in south-east Queensland., Med J Aust, 174, 150, 10.5694/j.1326-5377.2001.tb143195.x Sato, 2005, Amelioration of osteoporosis and hypovitaminosis d by sunlight exposure in hospitalized, elderly women with Alzheimer's disease: a randomized controlled trial., J Bone Miner Res, 20, 1327, 10.1359/JBMR.050402 Nesby-O'Dell, 2002, Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988–1994., Am J Clin Nutr, 76, 187, 10.1093/ajcn/76.1.187 Holick, 1989, Age, vitamin D, and solar ultraviolet., Lancet, 2, 1104, 10.1016/S0140-6736(89)91124-0 Wortsman, 2000, Decreased bioavailability of vitamin D in obesity., Am J Clin Nutr, 72, 690, 10.1093/ajcn/72.3.690 Zhou, 2006, Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia., J Clin Invest, 116, 1703, 10.1172/JCI27793 Apperly, 1941, The relation of solar radiation to cancer mortality in North America., Cancer Res, 1, 191 Garland, 1989, Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study., Lancet, 2, 1176, 10.1016/S0140-6736(89)91789-3 Gorham, 2005, Vitamin D and prevention of colorectal cancer., J Steroid Biochem Mol Biol, 97, 179, 10.1016/j.jsbmb.2005.06.018 Hanchette, 1992, Geographic patterns of prostate cancer mortality., Cancer, 70, 2861, 10.1002/1097-0142(19921215)70:12<2861::AID-CNCR2820701224>3.0.CO;2-G Grant, 2002, An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation., Cancer, 94, 1867, 10.1002/cncr.10427 Grant, 2006, The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates., Anticancer Res, 26, 2687 Giovannucci, 2006, Prospective study of predictors of vitamin D status and cancer incidence and mortality in men., J Natl Cancer Inst, 98, 451, 10.1093/jnci/djj101 Garland, 2006, The role of vitamin D in cancer prevention., Am J Public Health, 96, 252, 10.2105/AJPH.2004.045260 Ahonen, 2000, Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D levels (Finland)., Cancer Causes Control, 11, 847, 10.1023/A:1008923802001 Garland, 1985, Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men., Lancet, 9, 307, 10.1016/S0140-6736(85)91082-7 Lappe, 2007, Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial., Am J Clin Nutr, 85, 1586, 10.1093/ajcn/85.6.1586 Stene, 2000, Use of cod liver oil during pregnancy associated with lower risk of type I diabetes on the offspring., Diabetologia, 43, 1093, 10.1007/s001250051499 Ponsonby, 2002, Ultraviolet radiation and autoimmune disease: insights from epidemiological research., Toxicology, 181 Embry, 2000, Vitamin D and seasonal fluctuations of gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis., Ann Neurol, 48, 271, 10.1002/1531-8249(200008)48:2<271::AID-ANA28>3.0.CO;2-O Rostand, 1979, Ultraviolet light may contribute to geographic and racial blood pressure differences., Hypertension, 30, 150, 10.1161/01.HYP.30.2.150 Hypponen, 2001, Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study., Lancet, 358, 1500, 10.1016/S0140-6736(01)06580-1 Munger, 2004, Vitamin D intake and incidence of multiple sclerosis., Neurology, 62, 60, 10.1212/01.WNL.0000101723.79681.38 Merlino, 2004, Vitamin D intake is inversely associated with rheumatoid arthritis., Arthritis Rheum, 50, 72, 10.1002/art.11434 Krause, 1998, Ultraviolet B and blood pressure., Lancet, 352, 709, 10.1016/S0140-6736(05)60827-6 McGrath, 2002, Long-term trends in sunshine duration and its association with schizophrenia birth rates and age at first registration–data from Australia and the Netherlands., Schizophr Res, 54, 199, 10.1016/S0920-9964(01)00259-6 Gloth, 1999, Vitamin D vs. broad spectrum phototherapy in the treatment of seasonal effective disorder., J Nutr Health Aging, 3, 5 Bodnar, 2007, Maternal vitamin D deficiency increases the risk of preeclampsia., J Clin Endocrinol Metab, 92, 3517, 10.1210/jc.2007-0718 Chan, 2000, Vitamin D deficiency and susceptibility to tuberculosis., Calcif Tissue Int, 66, 476, 10.1007/s002230010095 Liu, 2006, Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response., Science, 3, 1770, 10.1126/science.1123933 Holick, 2006, photobiology, metabolism, mechanism of action, and clinical applications., 129 DeLuca, 2004, Overview of general physiologic features and functions of vitamin D., Am J Clin Nutr, 80, 1689S, 10.1093/ajcn/80.6.1689S Bikle, 2005, Vitamin D. role in skin and hair, 609 Cross, 2001, 25-Hydroxyvitamin D3-1-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis., Steroids, 66, 287, 10.1016/S0039-128X(00)00153-7 Tangpricha, 2001, 25-Hydroxyvitamin D-1α-hydroxylase in normal and malignant colon tissue., Lancet, 357, 1673, 10.1016/S0140-6736(00)04831-5 Schwartz, 1998, Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3., Cancer Epidemiol Biomarkers Prev, 7, 391 Mawer, 1994, Constitutive synthesis of 1,25-dihydroxyvitamin D3 by a human small cell lung cell line., J Clin Endocrinol Metab, 79, 554 Nagpal, 2005, Noncalcemic actions of vitamin D receptor ligands., Endocr Rev, 26, 662, 10.1210/er.2004-0002 Mantell, 2000, 1α,25-dihydroxyvitamin D3 inhibits angiogenesis in vitro and in vivo., Circ Res, 87, 214, 10.1161/01.RES.87.3.214 Li, 2003, Vitamin D regulation of the renin-angiotensin system., J Cell Biochem, 88, 327, 10.1002/jcb.10343 Mathieu, 2002, The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents., Trends Mol Med, 8, 174, 10.1016/S1471-4914(02)02294-3 Adorini, 2002, 1,25-Dihydroxyvitamin D3 analogs as potential therapies in transplantation., Curr Opin Investig Drugs, 3, 1458 Cantorna, 2004, Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system., Am J Clin Nutr, 80, 1717S, 10.1093/ajcn/80.6.1717S 1999 National Osteoporosis Foundation.Statement on calcium and vitamin D.Internet: http://www.nof.org/prevention/calcium/htm (accessed 16 November2007). Cheng, 2003, Association of low 25-hydroxyvitamin D concentrations with elevated parathyroid hormone concentrations and low cortical bone density in early pubertal and prepubertal Finnish girls., Am J Clin Nutr, 78, 485, 10.1093/ajcn/78.3.485 Outila, 2001, Vitamin D status affects serum parathyroid hormone concentrations during winter in female adolescents: associations with forearm bone mineral density., Am J Clin Nutr, 74, 206, 10.1093/ajcn/74.2.206 Guillemant, 1995, Vitamin D-dependent seasonal variation of PTH in growing male adolescents., Bone, 17, 513, 10.1016/8756-3282(95)00401-7 Lehtonen-Veromaa, 2002, The effect of conventional vitamin D2 supplementation on serum 25(OH)D concentration is weak among peripubertal Finnish girls: a 3-yr prospective study., Eur J Clin Nutr, 56, 431, 10.1038/sj.ejcn.1601330 Tangpricha, 2003, Fortification of orange juice with vitamin D: a novel approach to enhance vitamin D nutritional health., Am J Clin Nutr, 77, 1478, 10.1093/ajcn/77.6.1478 Vieth, 2007, The urgent need to reconsider recommendations for vitamin D nutrition intake., Am J Clin Nutr, 85, 649, 10.1093/ajcn/85.3.649 Holick MF, Biancuzzo RM, Chen TC, et al.Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab2007Dec 18 [Epub ahead of print]. Jones, 2007, Expanding role for vitamin D in chronic kidney disease: importance of blood 25-OH-D levels and extra-renal 1α-hydroxylase in the classical and nonclassical actions of 1α,25-dihydroxyvitamin D3., Semin Dial, 20, 316, 10.1111/j.1525-139X.2007.00302.x Tang, 1998, Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2., Am J Clin Nutr, 68, 854, 10.1093/ajcn/68.4.854 Armas, 2004, Vitamin D2 is much less effective than vitamin D3 in humans., J Clin Endocrinol Metab, 89, 5387, 10.1210/jc.2004-0360 Heaney, 2003, Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol., Am J Clin Nutr, 77, 204, 10.1093/ajcn/77.1.204 Loomis, 1967, Vitamin D, sunlight and natural selection., Science, 157, 501, 10.1126/science.157.3788.501 Wolpowitz, 2006, The vitamin D questions: how much do you need an how should you get it?, J Am Acad Dermatol, 54, 301, 10.1016/j.jaad.2005.11.1057 Binkley, 2004, Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization., J Clin Endocrinol Metab, 89, 3152, 10.1210/jc.2003-031979