The initial phase of fracture healing is specifically sensitive to mechanical conditions

Journal of Orthopaedic Research - Tập 21 - Trang 662-669 - 2003
Petra Klein1, Hanna Schell1, Florian Streitparth1, Markus Heller1, Jean-Pierre Kassi1, Frank Kandziora1, Hermann Bragulla2, Norbert P Haas1, Georg N Duda1
1Trauma and Reconstructive Surgery, Charité, Campus Virchow-Klinikum, Humboldt University of Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany
2Institute for Veterinary Anatomy, Free University of Berlin, D-14195 Berlin, Germany

Tóm tắt

AbstractInterfragmentary movements affect the quality and quantity of callus formation. The mounting plane of monolateral external fixators may give direction to those movements. Therefore, the aim of this study was to determine the influence of the fixator mounting plane on the process of fracture healing.Identically configured fixators were mounted either medially or anteromedially on the tibiae of sheep. Interfragmentary movements and ground reaction forces were evaluated in vivo during a nine week period. Histomorphological and biomechanical parameters described the bone healing processes.Changing only the mounting plane led to a modification of interfragmentary movements in the initial healing phase. The difference in interfragmentary movements between the groups was only significant during the first post‐operative period. However, these initial differences in mechanical conditions influenced callus tissue formation significantly. The group with the anteromedially mounted fixator, initially showing significantly more interfragmentary movements, ended up with a significantly smaller callus diameter and a significantly higher callus stiffness as a result of advanced fracture healing. This demonstrates that the initial phase of healing is sensitive to mechanical conditions and influences the course of healing. Therefore, initial mechanical stability of an osteosynthesis should be considered an important factor in clinical fracture treatment. © 2003 Orthopaedic Research Society. Published by Elsevier Science Ltd. All rights reserved.

Tài liệu tham khảo

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Journal of Orthopaedic Research

Tập 21

662-669

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