Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms
Tóm tắt
Tài liệu tham khảo
Klampfl, 2013, Somatic mutations of calreticulin in myeloproliferative neoplasms., N Engl J Med, 369, 2379, 10.1056/NEJMoa1311347
Nangalia, 2013, Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2., N Engl J Med, 369, 2391, 10.1056/NEJMoa1312542
Rumi, 2014, JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes., Blood, 123, 1544, 10.1182/blood-2013-11-539098
Shirane, 2015, JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms., Haematologica, 100, e46, 10.3324/haematol.2014.115113
Rotunno, 2014, Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia., Blood, 123, 1552, 10.1182/blood-2013-11-538983
Tefferi, 2014, CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons., Leukemia, 28, 1472, 10.1038/leu.2014.3
Fu, 2014, Analysis of calreticulin mutations in Chinese patients with essential thrombocythemia: clinical implications in diagnosis, prognosis and treatment., Leukemia, 28, 1912, 10.1038/leu.2014.138
Tefferi, 2014, Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact., Leukemia, 28, 1568, 10.1038/leu.2014.83
Cleyrat, 2014, Mpl traffics to the cell surface through conventional and unconventional routes., Traffic, 15, 961, 10.1111/tra.12185
Komatsu, 1996, Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO., Blood, 87, 4552, 10.1182/blood.V87.11.4552.bloodjournal87114552
Komatsu, 1993, Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7., Blood, 82, 456, 10.1182/blood.V82.2.456.456
Sunami, 2013, Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells., PLoS One, 8, e57633, 10.1371/journal.pone.0057633
Schneider, 2012, NIH Image to ImageJ: 25 years of image analysis., Nat Methods, 9, 671, 10.1038/nmeth.2089
Okita, 2013, An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells., Stem Cells, 31, 458, 10.1002/stem.1293
Takayama, 2012, In vitro generation of megakaryocytes and platelets from human embryonic stem cells and induced pluripotent stem cells., Methods Mol Biol, 788, 205, 10.1007/978-1-61779-307-3_15
Komatsu, 1991, Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival., Cancer Res, 51, 341
Hou, 2013, Strange attractors: DAMPs and autophagy link tumor cell death and immunity., Cell Death Dis, 4, e966, 10.1038/cddis.2013.493
Michalak, 2009, Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum., Biochem J, 417, 651, 10.1042/BJ20081847
Zamanian, 2013, Calreticulin and cancer., Pathol Oncol Res, 19, 149, 10.1007/s12253-012-9600-2
Patel, 2015, Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib., Blood, 126, 790, 10.1182/blood-2015-03-633404
Brooks, 2014, Mechanism of activation of protein kinase JAK2 by the growth hormone receptor., Science, 344, 1249783, 10.1126/science.1249783
Defour, 2013, Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation., Proc Natl Acad Sci USA, 110, 2540, 10.1073/pnas.1211560110
Dupuis, 1993, The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes., J Exp Med, 177, 1, 10.1084/jem.177.1.1
Gold, 2010, Calreticulin: non-endoplasmic reticulum functions in physiology and disease., FASEB J, 24, 665, 10.1096/fj.09-145482
Takei
Waters, 2015, JAK2 activation by growth hormone and other cytokines., Biochem J, 466, 1, 10.1042/BJ20141293
Matthews, 2011, Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation., FASEB J, 25, 2234, 10.1096/fj.10-178673