Separation of diffusion and slow flow effects by use of flow rephasing and dephasing

Magnetic Resonance in Medicine - Tập 24 Số 1 - Trang 109-122 - 1992
Naonobu Fujita1, K. Harada2, Kosuke Sakurai2, Y Akai2, T Kozuka2
1Department of Radiology, Osaka University, Medical School, Japan
2Department of Radiology Osaka University Medical School 1‐1‐50 Fukushima, Fukushima‐ku, Osaka 553. Japan.

Tóm tắt

AbstractSpin‐echo signal intensity alterations due to diffusion and slow flow are investigated in connection with modified Stejskal‐Tanner pulse sequences for 2D Fourier MR imaging, one for flow rephasing and the other for flow dephasing gradient waveforms. The theoretical considerations and experimental results concerning the diffusion coefficient measurements of slowly flowing material by these sequences are summarized as follows: (a) By using the flow dephasing sequence with different diffusion and flow‐sensitive gradients, slow flow effects can be distinguished from diffusion effects based on the quantitative difference between the diffusion‐and flow‐sensitive gradient amplitude dependences of these processes. (b) By using the combination of the flow rephasing and dephasing sequences with the same diffusion sensitivity, slow flow effects can be distinguished from diffusion effects directly based on their qualitative difference. By use of the latter approach, several in vivo images are also presented, which mainly represent macroscopic motions of spins, including slow flow such as tissue perfusion. © 1992 Academic Press, Inc.

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Tài liệu tham khảo

10.1148/radiology.161.2.3763909

10.1118/1.596093

10.1148/radiology.168.2.3393671

10.1002/mrm.1910100307

10.1063/1.1696526

10.1080/00268976900101131

10.1002/mrm.1910140219

10.1063/1.1695690

Caro C. G., 1976, The Mechanics of the Circulation, 130

10.1055/s-0038-1661576

10.1088/0031-9155/30/4/009

10.1016/0022-2364(80)90095-5

10.1143/JPSJ.47.1999

10.1002/mrm.1910150210

10.1109/TMI.1986.4307763

10.1097/00004728-198705000-00001

10.1016/0006-8993(81)90619-3

10.1002/mrm.1910140213

Moriguchi S., 1960, Mathematical Formulas, 22