Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

Nature Medicine - Tập 21 Số 6 - Trang 638-646 - 2015
Iván Mascanfroni1, Maisa C. Takenaka1, Ada Yeste1, Bonny Patel1, Jing Liao2, Jessica E. Kenison1, Shafiuddin Siddiqui1, Alexandre Salgado Basso3, Leo E. Otterbein2, Drew M. Pardoll4, Fan Pan4, Avner Priel5, Clary B. Clish6, Simon C. Robson2, Francisco J. Quintana1
1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
2Division of Gastroenterology, Hepatology and Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
3Department of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil
4Immunology and Hematopoiesis Division, Department of Oncology and Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
5Department of Physics, University of Alberta, Edmonton, Alberta, Canada
6Center for Proteomics, The Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, Massachusetts, USA.

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