High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation

Blood - Tập 125 - Trang 199-205 - 2015
Doris M. Ponce1,2, Patrick Hilden3, Christen Mumaw4, Sean M. Devlin3, Marissa Lubin1, Sergio Giralt1,2, Jenna D. Goldberg1,2, Alan Hanash1,2, Katharine Hsu1,2, Robert Jenq1,2, Miguel-Angel Perales1,2, Craig Sauter1,2, MarcelR. M. van den Brink1,2, James W. Young1,2, Renier Brentjens2,5, Nancy A. Kernan6, Susan E. Prockop6, Richard J. O’Reilly2,6, Andromachi Scaradavou6, Sophie Paczesny4
1Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2Department of Medicine, Weill Cornell Medical College, New York, NY
3Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
4Departments of Pediatrics and Immunology, Melvin and Bren Simon Cancer Center and Wells Center for Pediatric Research, Indiana University, Indianapolis, IN
5Leukemia Service, Department of Medicine,
6Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY

Tóm tắt

Key Points

ST2 is independently associated with aGVHD after day 28 in cord blood transplantation recipients. High ST2 levels predict for increased TRM in cord blood transplantation recipients.


Tài liệu tham khảo

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