Nuclear Actin and Actin-Related Proteins in Chromatin Remodeling

Annual Review of Biochemistry - Tập 71 Số 1 - Trang 755-781 - 2002
Ivan Olave1, Samara L. Reck‐Peterson2, Gerald R. Crabtree2
1Department of Developmental Biology and Department of Pathology, Howard Hughes Medical Institute at Stanford University, Stanford, California 94305, USA.
2Department of Developmental Biology and Department of Pathology, Howard Hughes Medical Institute at Stanford University, Stanford, California 94305,,

Tóm tắt

▪ Abstract  The existence and function of actin in the nucleus has been hotly debated for forty years. Recently, β-actin was found to be a component of mammalian SWI/SNF-like BAF chromatin remodeling complexes and still more recently other SWI/SNF-related chromatin remodeling complexes in yeast, flies, and man. Although the function of actin in these chromatin remodeling complexes is only starting to be explored, the fact that actin is one of the most regulated proteins in the cell suggests that control of nuclear actin may be a critical regulatory point in the control of chromatin remodeling. Actin rapidly shuttles between the nucleus and the cytoplasm offering additional sites and modes of regulation. In addition, actin-related proteins (Arps) are also components of these chromatin remodeling complexes and have been implicated in transcriptional control in yeast. The observation that the BAF chromatin remodeling complex in which actin was originally identified, is also a human tumor suppressor complex necessary for the actions of the retinoblastoma protein indicates that the study of nuclear actin is likely to contribute to understanding cell growth control.

Từ khóa


Tài liệu tham khảo

10.1146/annurev.cb.10.110194.001231

10.1146/annurev.biophys.29.1.545

10.1016/S0955-0674(99)00062-9

10.1016/0092-8674(77)90152-0

10.1016/0092-8674(79)90223-X

Gonsior SM, 1999, J. Cell. Sci., 112, 797, 10.1242/jcs.112.6.797

10.1073/pnas.84.15.5262

10.1083/jcb.138.4.771

10.1016/0092-8674(82)90446-9

10.1083/jcb.152.5.895

10.1083/jcb.153.1.229

10.1093/emboj/17.6.1635

10.1016/S0092-8674(00)81633-5

Papoulas O, 1998, Development, 125, 3955, 10.1242/dev.125.20.3955

10.1038/35020123

10.1016/S1097-2765(00)80258-0

10.1016/S0092-8674(00)00051-9

10.1016/S0092-8674(01)00450-0

10.1016/S1097-2765(00)80162-8

10.1083/jcb.126.2.403

10.1016/S0960-9822(99)80095-5

10.1128/MCB.20.6.1899-1910.2000

10.1038/366170a0

10.1002/j.1460-2075.1996.tb00921.x

10.1101/gad.10.17.2117

10.1002/j.1460-2075.1993.tb06112.x

10.1016/0092-8674(94)90405-7

10.1016/S0092-8674(01)00446-9

10.1016/0092-8674(92)90191-E

Elfring LK, 1998, Genetics, 148, 251, 10.1093/genetics/148.1.251

Brizuela BJ, 1994, Genetics, 137, 803, 10.1093/genetics/137.3.803

Ruhf ML, 2001, Development, 128, 1429, 10.1242/dev.128.8.1429

10.1046/j.1365-2958.1999.01390.x

10.1073/pnas.95.22.12924

10.1038/28886

10.1128/MCB.19.1.855

10.1128/MCB.19.9.5952

10.1101/gad.10.5.604

10.1091/mbc.10.8.2595

10.1038/ng725

Neigeborn L, 1984, Genetics, 108, 845, 10.1093/genetics/108.4.845

10.1016/0022-2836(84)90315-2

10.1016/0092-8674(87)90190-5

10.1126/science.8016655

10.1074/jbc.273.37.23641

10.1016/S0092-8674(00)80740-0

10.1101/gad.13.11.1412

10.1093/emboj/18.8.2254

10.1093/emboj/18.11.3101

10.1016/S0092-8674(00)81820-6

Winston F, 1984, Genetics, 107, 179, 10.1093/genetics/107.2.179

10.1016/0168-9525(92)90300-S

10.1016/0076-6879(89)70065-3

10.1016/S0076-6879(96)74024-7

10.1038/370477a0

10.1038/370481a0

10.1074/jbc.272.19.12642

10.1128/MCB.20.9.3058-3068.2000

10.1016/S1097-2765(00)80315-9

10.1016/0092-8674(95)90216-3

10.1016/S0092-8674(00)80796-5

10.1016/S0092-8674(00)80797-7

10.1002/j.1460-2075.1992.tb05365.x

10.1073/pnas.91.22.10275

10.1038/23506

10.1073/pnas.95.9.4947

10.1016/S0092-8674(00)80551-6

10.1016/S0092-8674(00)81217-9

10.1016/S0092-8674(00)81218-0

10.1016/S0092-8674(00)00215-4

10.1038/sj.onc.1204332

10.1146/annurev.cellbio.15.1.341

10.1146/annurev.biochem.70.1.649

10.1091/mbc.6.10.1263

Frankel S, 1997, J. Cell Sci., 110, 1999, 10.1242/jcs.110.17.1999

10.1002/1521-1878(200007)22:7<666::AID-BIES9>3.0.CO;2-Y

10.1016/S0092-8674(00)80732-1

10.1146/annurev.biochem.70.1.649

Rando OJ, 2002, Proc. Natl. Acad. Sci. USA.

10.1146/annurev.biochem.68.1.459

10.1083/jcb.147.5.921

10.1016/S0960-9822(00)80022-6

10.1016/0092-8674(93)80041-C

10.1016/0003-9861(84)90226-1

10.1042/bj2480765

10.1016/S0065-2571(00)00017-0

10.1073/pnas.041614598

10.1016/S0092-8674(00)00195-1

10.1146/annurev.biochem.67.1.481

10.1002/j.1460-2075.1991.tb04883.x

10.1126/science.285.5424.96

10.1126/science.287.5460.2026

10.1002/j.1460-2075.1994.tb06519.x

10.1038/70319

10.1016/S0014-5793(00)02318-8

10.1073/pnas.021558098

10.1073/pnas.96.5.2135

10.1074/jbc.271.1.478

10.1038/18044

10.1126/science.281.5382.1505

10.1016/S0962-8924(99)01713-4

10.1002/cm.970260306

10.1083/jcb.139.5.1255

Wulfkuhle JD, 1999, J. Cell Sci., 112, 2125, 10.1242/jcs.112.13.2125

Onoda K, 1993, J. Biol. Chem., 268, 4106, 10.1016/S0021-9258(18)53586-9

10.1074/jbc.274.48.33827

10.1074/jbc.271.42.26276

Samstag Y, 1996, J. Immunol., 156, 4167, 10.4049/jimmunol.156.11.4167

10.1074/jbc.270.29.17582

10.1046/j.1365-2443.1996.05005.x

10.1038/31729

10.1038/31735

Carotenuto R, 1997, J. Cell Sci., 110, 2683, 10.1242/jcs.110.21.2683

10.1074/jbc.272.27.17176

10.1126/science.290.5490.337

10.1073/pnas.85.21.8136

10.1016/S0925-4773(97)00081-6

10.1128/MCB.19.2.1159

10.1038/35073039

10.1016/0168-9525(90)90303-N

10.1146/annurev.ge.29.120195.001445

10.1101/gad.11.15.1949

10.1101/gad.854300

10.1101/gad.11.24.3286

10.1073/pnas.050407197

Staehling-Hampton K, 1999, Genetics, 153, 275, 10.1093/genetics/153.1.275

Vazquez M, 1999, Development, 126, 733, 10.1242/dev.126.4.733

10.1093/emboj/17.23.6979

10.1128/MCB.16.4.1576

10.1128/MCB.19.2.1460

10.1016/S0092-8674(00)80625-X

10.1038/28212

10.1073/pnas.68.4.820

10.1038/sj.onc.1203168

10.1086/302639

10.1093/embo-reports/kvd129

10.1016/S1097-2765(00)00127-1

10.1016/S0092-8674(00)81011-9

10.1016/0092-8674(82)90344-0

10.1128/MCB.4.10.1961

10.1073/pnas.88.7.2687

10.1016/0092-8674(92)90192-F

10.1128/MCB.19.4.2515

10.1128/MCB.20.23.8879-8888.2000

10.1016/S1097-2765(00)80299-3

10.1016/S0092-8674(00)81758-4

10.1101/gad.13.18.2388

10.1006/geno.1998.5557

10.1073/pnas.97.9.4772

10.1101/gad.12.20.3206

10.1038/41587

Thông tin
Thông tin xuất bản

Annual Review of Biochemistry

Tập 71 Số 1

755-781

Thông tin tác giả