Dietary Patterns and Risk of Dementia: a Systematic Review and Meta-Analysis of Cohort Studies

Lei Cao1, Lan Tan2,1, Hui-Fu Wang1, Teng Jiang3, Xi-Chen Zhu1, Huan Lu1, Meng-Shan Tan2, Jin‐Tai Yu2,4,1
1Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, China
2Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China
3Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
4Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Ogawa S (2014) Nutritional management of older adults with cognitive decline and dementia. Geriatr Gerontol Int 14(Suppl 2):17–22. doi: 10.1111/ggi.12252

Solfrizzi V, Capurso C, D'Introno A, Colacicco AM, Santamato A, Ranieri M, Fiore P, Capurso A et al (2008) Lifestyle-related factors in predementia and dementia syndromes. Expert Rev Neurother 8(1):133–158. doi: 10.1586/14737175.8.1.133

Sampson EL (2010) Palliative care for people with dementia. Br Med Bull 96:159–174. doi: 10.1093/bmb/ldq024

Jiang T, Yu JT, Tian Y, Tan L (2013) Epidemiology and etiology of Alzheimer's disease: from genetic to Non- genetic factors. Curr Alzheimer Res 10(8):852–867

Eskelinen MH, Ngandu T, Tuomilehto J, Soininen H, Kivipelto M (2011) Midlife healthy-diet index and late-life dementia and Alzheimer’s disease. Dement Geriatr Cogn Disord Extra 1(1):103–112. doi: 10.1159/000327518

Alles B, Samieri C, Feart C, Jutand MA, Laurin D, Barberger-Gateau P (2012) Dietary patterns: a novel approach to examine the link between nutrition and cognitive function in older individuals. Nutr Res Rev 25(2):207–222. doi: 10.1017/S0954422412000133

Sofi F, Abbate R, Gensini GF, Casini A (2010) Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr 92(5):1189–1196. doi: 10.3945/ajcn.2010.29673

Crichton GE, Bryan J, Murphy KJ (2013) Dietary antioxidants, cognitive function and dementia—a systematic review. Plant Foods Hum Nutr 68(3):279–292. doi: 10.1007/s11130-013-0370-0

Gu Y, Nieves JW, Stern Y, Luchsinger JA, Scarmeas N (2010) Food combination and Alzheimer disease risk: a protective diet. Arch Neurol 67(6):699–706. doi: 10.1001/archneurol.2010.84

Etgen T, Sander D, Bickel H, Sander K, Forstl H (2012) Vitamin D deficiency, cognitive impairment and dementia: a systematic review and meta-analysis. Dement Geriatr Cogn Disord 33(5):297–305. doi: 10.1159/000339702

Peters R, Poulter R, Warner J, Beckett N, Burch L, Bulpitt C (2008) Smoking, dementia and cognitive decline in the elderly, a systematic review. BMC Geriatr 8:36. doi: 10.1186/1471-2318-8-36

Panza F, Capurso C, D’Introno A, Colacicco AM, Frisardi V, Lorusso M, Santamato A, Seripa D et al (2009) Alcohol drinking, cognitive functions in older age, predementia, and dementia syndromes. J Alzheimers Dis 17(1):7–31. doi: 10.3233/JAD-2009-1009

Zhu XC, Yu Y, Wang HF, Jiang T, Cao L, Wang C, Wang J, Tan CC et al (2014) Physiotherapy intervention in Alzheimer’s disease: systematic review and meta-analysis. J Alzheimers Dis. doi: 10.3233/JAD-141377

Huang TL, Zandi PP, Tucker KL, Fitzpatrick AL, Kuller LH, Fried LP, Burke GL, Carlson MC (2005) Benefits of fatty fish on dementia risk are stronger for those without APOE epsilon4. Neurology 65(9):1409–1414. doi: 10.1212/01.wnl.0000183148.34197.2e

Roberts RO, Geda YE, Cerhan JR, Knopman DS, Cha RH, Christianson TJ, Pankratz VS, Ivnik RJ et al (2010) Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment. Dement Geriatr Cogn Disord 29(5):413–423. doi: 10.1159/000305099

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA (2002) Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA 287(24):3230–3237

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J (2003) Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 60(7):940–946. doi: 10.1001/archneur.60.7.940

Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA (2005) Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr 81(2):508–514

Corrada MM, Kawas CH, Hallfrisch J, Muller D, Brookmeyer R (2005) Reduced risk of Alzheimer’s disease with high folate intake: the Baltimore longitudinal study of aging. Alzheimers Dement 1(1):11–18. doi: 10.1016/j.jalz.2005.06.001

Laurin D, Masaki KH, Foley DJ, White LR, Launer LJ (2004) Midlife dietary intake of antioxidants and risk of late-life incident dementia: the Honolulu-Asia aging study. Am J Epidemiol 159(10):959–967

Luchsinger JA, Tang MX, Shea S, Mayeux R (2003) Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol 60(2):203–208

Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R (2007) Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol 64(1):86–92. doi: 10.1001/archneur.64.1.86

Zandi PP, Anthony JC, Khachaturian AS, Stone SV, Gustafson D, Tschanz JT, Norton MC, Welsh-Bohmer KA et al (2004) Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the cache county study. Arch Neurol 61(1):82–88. doi: 10.1001/archneur.61.1.82

Nelson C, Wengreen HJ, Munger RG, Corcoran CD (2009) Dietary folate, vitamin B-12, vitamin B-6 and incident Alzheimer’s disease: the cache county memory, health and aging study. J Nutr Health Aging 13(10):899–905

Dai Q, Borenstein AR, Wu Y, Jackson JC, Larson EB (2006) Fruit and vegetable juices and Alzheimer’s disease: the Kame project. Am J Med 119(9):751–759. doi: 10.1016/j.amjmed.2006.03.045

Scarmeas N, Stern Y, Mayeux R, Manly JJ, Schupf N, Luchsinger JA (2009) Mediterranean diet and mild cognitive impairment. Arch Neurol 66(2):216–225. doi: 10.1001/archneurol.2008.536

Scarmeas N, Stern Y, Tang MX, Mayeux R, Luchsinger JA (2006) Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 59(6):912–921. doi: 10.1002/ana.20854

Merchant C, Tang MX, Albert S, Manly J, Stern Y, Mayeux R (1999) The influence of smoking on the risk of Alzheimer’s disease. Neurology 52(7):1408–1412

Luchsinger JA, Tang MX, Siddiqui M, Shea S, Mayeux R (2004) Alcohol intake and risk of dementia. J Am Geriatr Soc 52(4):540–546. doi: 10.1111/j.1532-5415.2004.52159.x

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R (2005) Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology 65(4):545–551. doi: 10.1212/01.wnl.0000172914.08967.dc

Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PH, Fried L, Kestenbaum BR et al (2014) Vitamin D and the risk of dementia and Alzheimer disease. Neurology 83(10):920–928. doi: 10.1212/WNL.0000000000000755

Devore EE, Grodstein F, van Rooij FJ, Hofman A, Rosner B, Stampfer MJ, Witteman JC, Breteler MM (2009) Dietary intake of fish and omega-3 fatty acids in relation to long-term dementia risk. Am J Clin Nutr 90(1):170–176. doi: 10.3945/ajcn.2008.27037

Devore EE, Grodstein F, van Rooij FJ, Hofman A, Stampfer MJ, Witteman JC, Breteler MM (2010) Dietary antioxidants and long-term risk of dementia. Arch Neurol 67(7):819–825. doi: 10.1001/archneurol.2010.144

Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM (2002) Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 287(24):3223–3229

Ott A, Slooter AJ, Hofman A, van Harskamp F, Witteman JC, Van Broeckhoven C, van Duijn CM, Breteler MM (1998) Smoking and risk of dementia and Alzheimer’s disease in a population-based cohort study: the Rotterdam study. Lancet 351(9119):1840–1843

Reitz C, den Heijer T, van Duijn C, Hofman A, Breteler MM (2007) Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam study. Neurology 69(10):998–1005. doi: 10.1212/01.wnl.0000271395.29695.9a

Ruitenberg A, van Swieten JC, Witteman JC, Mehta KM, van Duijn CM, Hofman A, Breteler MM (2002) Alcohol consumption and risk of dementia: the Rotterdam study. Lancet 359(9303):281–286. doi: 10.1016/S0140-6736(02)07493-7

Launer LJ, Andersen K, Dewey ME, Letenneur L, Ott A, Amaducci LA, Brayne C, Copeland JR et al (1999) Rates and risk factors for dementia and Alzheimer’s disease: results from EURODEM pooled analyses. EURODEM incidence research group and work groups. European studies of dementia. Neurology 52(1):78–84

Barberger-Gateau P, Raffaitin C, Letenneur L, Berr C, Tzourio C, Dartigues JF, Alperovitch A (2007) Dietary patterns and risk of dementia: the three-city cohort study. Neurology 69(20):1921–1930. doi: 10.1212/01.wnl.0000278116.37320.52

Commenges D, Scotet V, Renaud S, Jacqmin-Gadda H, Barberger-Gateau P, Dartigues JF (2000) Intake of flavonoids and risk of dementia. Eur J Epidemiol 16(4):357–363

Feart C, Samieri C, Rondeau V, Amieva H, Portet F, Dartigues JF, Scarmeas N, Barberger-Gateau P (2009) Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA 302(6):638–648. doi: 10.1001/jama.2009.1146

Rondeau V, Commenges D, Jacqmin-Gadda H, Dartigues JF (2000) Relation between aluminum concentrations in drinking water and Alzheimer’s disease: an 8-year follow-up study. Am J Epidemiol 152(1):59–66

Rondeau V, Jacqmin-Gadda H, Commenges D, Helmer C, Dartigues JF (2009) Aluminum and silica in drinking water and the risk of Alzheimer’s disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort. Am J Epidemiol 169(4):489–496. doi: 10.1093/aje/kwn348

Wang HX, Fratiglioni L, Frisoni GB, Viitanen M, Winblad B (1999) Smoking and the occurrence of Alzheimer’s disease: cross-sectional and longitudinal data in a population-based study. Am J Epidemiol 149(7):640–644

Mehlig K, Skoog I, Guo X, Schutze M, Gustafson D, Waern M, Ostling S, Bjorkelund C et al (2008) Alcoholic beverages and incidence of dementia: 34-year follow-up of the prospective population study of women in Goteborg. Am J Epidemiol 167(6):684–691. doi: 10.1093/aje/kwm366

Huang W, Qiu C, Winblad B, Fratiglioni L (2002) Alcohol consumption and incidence of dementia in a community sample aged 75 years and older. J Clin Epidemiol 55(10):959–964

Solfrizzi V, Colacicco AM, D’Introno A, Capurso C, Del Parigi A, Capurso SA, Argentieri G, Capurso A et al (2006) Dietary fatty acids intakes and rate of mild cognitive impairment. The Italian longitudinal study on aging. Exp Gerontol 41(6):619–627. doi: 10.1016/j.exger.2006.03.017

Solfrizzi V, D’Introno A, Colacicco AM, Capurso C, Del Parigi A, Baldassarre G, Scapicchio P, Scafato E et al (2007) Alcohol consumption, mild cognitive impairment, and progression to dementia. Neurology 68(21):1790–1799. doi: 10.1212/01.wnl.0000262035.87304.89

Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A, Ferrucci L, Melzer D (2010) Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med 170(13):1135–1141. doi: 10.1001/archinternmed.2010.173

Peters S, Reid A, Fritschi L, de Klerk N, Musk AW (2013) Long-term effects of aluminium dust inhalation. Occup Environ Med 70(12):864–868. doi: 10.1136/oemed-2013-101487

Simons LA, Simons J, McCallum J, Friedlander Y (2006) Lifestyle factors and risk of dementia: Dubbo study of the elderly. Med J Aust 184(2):68–70

Cervilla JA, Prince M, Mann A (2000) Smoking, drinking, and incident cognitive impairment: a cohort community based study included in the gospel Oak project. J Neurol Neurosurg Psychiatry 68(5):622–626

Doll R, Peto R, Boreham J, Sutherland I (2000) Smoking and dementia in male British doctors: prospective study. BMJ 320(7242):1097–1102

Kroger E, Verreault R, Carmichael PH, Lindsay J, Julien P, Dewailly E, Ayotte P, Laurin D (2009) Omega-3 fatty acids and risk of dementia: the Canadian study of health and aging. Am J Clin Nutr 90(1):184–192. doi: 10.3945/ajcn.2008.26987

Afzal S, Bojesen SE, Nordestgaard BG (2014) Reduced 25-hydroxyvitamin D and risk of Alzheimer’s disease and vascular dementia. Alzheimers Dement 10(3):296–302. doi: 10.1016/j.jalz.2013.05.1765

Otaegui-Arrazola A, Amiano P, Elbusto A, Urdaneta E, Martinez-Lage P (2014) Diet, cognition, and Alzheimer’s disease: food for thought. Eur J Nutr 53(1):1–23. doi: 10.1007/s00394-013-0561-3

Kalmijn S, Feskens EJ, Launer LJ, Kromhout D (1997) Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 145(1):33–41

Morris MC, Evans DA, Schneider JA, Tangney CC, Bienias JL, Aggarwal NT (2006) Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer’s disease. J Alzheimers Dis 9(4):435–443

Wang HX, Wahlin A, Basun H, Fastbom J, Winblad B, Fratiglioni L (2001) Vitamin B(12) and folate in relation to the development of Alzheimer’s disease. Neurology 56(9):1188–1194

Grant WB (2009) Does vitamin D reduce the risk of dementia? J Alzheimers Dis 17(1):151–159. doi: 10.3233/JAD-2009-1024

Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Herrmann FR, Beauchet O (2012) Higher vitamin D dietary intake is associated with lower risk of Alzheimer’s disease: a 7-year follow-up. J Gerontol Ser A Biol Med Sci 67(11):1205–1211. doi: 10.1093/gerona/gls107

Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO (2014) Association of Mediterranean diet with mild cognitive impairment and Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimers Dis 39(2):271–282. doi: 10.3233/JAD-130830

Carmelli D, Swan GE, Reed T, Schellenberg GD, Christian JC (1999) The effect of apolipoprotein E epsilon4 in the relationships of smoking and drinking to cognitive function. Neuroepidemiology 18(3):125–133, 26204

Dufouil C, Tzourio C, Brayne C, Berr C, Amouyel P, Alperovitch A (2000) Influence of apolipoprotein E genotype on the risk of cognitive deterioration in moderate drinkers and smokers. Epidemiology 11(3):280–284

Loef M, Walach H (2012) Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging 16(7):626–630

Peters R, Peters J, Warner J, Beckett N, Bulpitt C (2008) Alcohol, dementia and cognitive decline in the elderly: a systematic review. Age Ageing 37(5):505–512. doi: 10.1093/ageing/afn095

Luchsinger JA, Tang MX, Shea S, Mayeux R (2002) Caloric intake and the risk of Alzheimer disease. Arch Neurol 59(8):1258–1263

Geda YE, Ragossnig M, Roberts LA, Roberts RO, Pankratz VS, Christianson TJ, Mielke MM, Levine JA et al (2013) Caloric intake, aging, and mild cognitive impairment: a population-based study. J Alzheimers Dis 34(2):501–507. doi: 10.3233/JAD-121270