The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Vleminckx, K., Vakaet, L. Jr, Mareel, M., Fiers, W. & van Roy, F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66, 107–119 (1991).
Perl, A. K., Wilgenbus, P., Dahl, U., Semb, H. & Christofori, G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392, 190–193 (1998).
Shiozaki, H., Oka, H., Inoue, M., Tamura, S. & Monden, M. E-cadherin mediated adhesion system in cancer cells. Cancer 77, 1605–1613 (1996).
Hennig, G., Lowrick, O., Birchmeier, W. & Behrens, J. Mechanisms identified in the transcriptional control of epithelial gene expression. J. Biol. Chem. 271, 595–602 (1996).
Ji, X., Woodard, A. S., Rimm, D. L. & Fearon, E. R. Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell. Growth Differ. 8, 773–778 (1997).
Giroldi, L. A. et al. Role of E boxes in the repression of E-cadherin expression. Biochem. Biophys. Res. Commun. 241, 453–458 (1997).
Mauhin, V., Lutz, Y., Dennefeld, C. & Alberga, A. Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL. Nucleic Acids Res. 21, 3951–3957 (1993).
Nakayama, H., Scott, I. C. & Cross, J. C. The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor. Dev. Biol. 199, 150–163 (1998).
Leptin, M. & Grunewald, B. Cell shape changes during gastrulation in Drosophila. Development 110, 73–84 (1990).
Smith, D. E., del Amo, F. F. & Gridley, T. Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles in postimplantation development. Development 116, 1033–1039 (1992).
Oda, H., Tsukita, S., & Takeichi, M. Dynamic behaviour of the cadherin-based cell-cell adhesion system during Drosophila gastrulation. Dev. Biol. 203, 435–450 (1998).
Sefton, M., Sanchez, S. & Nieto, M. A. Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo. Development 125, 3111–3121 (1998).
Nieto, M. A., Sargent, M. G., Wilkinson, D. G. & Cooke, J. Control of cell behaviour during vertebrate development by Slug, a zinc finger gene. Science 264, 835–839 (1994).
Grimes, H. L., Chan, T. O., Zweidler-McKay, P. A., Tong, B. & Tsichlis, P. N. The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol. Cell. Biol. 16, 6263–6272 (1996).
Birchmeier, C., Birchmeier, W. & Brand-Saberi, B. Epithelial-mesenchymal transitions in cancer progression. Acta Anat. 156, 217–226 (1996).
Damjanov, I., Damjanov, A. & Damsky C. H. Developmentally regulated expression of the cell-cell adhesion glycoprotein Cell-CAM 120/80 in peri-implantation mouse embryos and extraembryonic membranes. Dev. Biol. 116, 194–202 (1986).
Burdsal, C. A., Damsky, C. H. & Pedersen, R. A. The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development 118, 829–844 (1993).
Sorokin, L., Sonnenberg, A., Aumailley, M., Timpl, R., & Ekblom, P. Recognition of the laminin E8 cell-binding site by an integrin possessing the α6 integrin subunit is essential for epithelial polarization in developing kidney. J. Cell. Biol. 111, 1265–1273 (1990).
Gossen, M. & Bujard, H. Tight control of gene expression in mammalian cells by tetracycline responsive promoters. Proc. Natl Acad. Sci. USA 89, 5547–5551 (1992).
Schreiber, E., Matthias, P., Muller, M. M. & Schaffner, W. Rapid detection of octamer binding proteins with "mini-extracts" from a small number of cells. Nucleic Acids Res. 17, 6419 (1989).