β2‐Adrenergic receptor polymorphism and nitric oxide‐dependent forearm blood flow responses to isoproterenol in humans
Tóm tắt
Polymorphisms in the gene encoding the β2‐adrenoceptor have been associated with interindividual differences in blood pressure and the diagnosis of hypertension. A common polymorphism resulting in a change from arginine to glycine at amino acid 16 (Arg16 → Gly) enhances agonist‐promoted downregulation of receptor expression
Từ khóa
Tài liệu tham khảo
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