The effect of yogurt fortified with Lactobacillus acidophilus and Bifidobacterium sp. probiotic in patients with lactose intolerance

Food Science and Nutrition - Tập 9 Số 3 - Trang 1704-1711 - 2021
Seyed Jalil Masoumi1,2, Davood Mehrabani3,4,5, Mehdi Saberifiroozi6, Raimund Erbel1, Fariba Moradi7, Masoud Najafi8
1Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Science, Shiraz, Iran
3Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4Comparative and Experimental Medicine Center Shiraz University of Medical Sciences Shiraz Iran
5Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
6Digestive Disease Research Center Digestive Disease Research Institute Tehran University of Medical Science Tehran Iran
7Office of Vice President for Health Affairs Shiraz University of Medical Sciences Shiraz Iran
8Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

Tóm tắt

AbstractThis study assessed the effect of probiotic yogurt fortified with Lactobacillus acidophilus and Bifidobacterium sp. in patients with lactose intolerance. Fifty‐five patients suffering from lactose intolerance were randomly divided into control group of 28 lactose intolerance patients who received nonprobiotic yogurt (100 ml) and experimental group consisted of 27 lactose intolerance patients who received probiotic yogurt fortified (100 ml) with L. acidophilus and Bifidobacterium sp. Each individual received yogurt for one week. Lactose intolerance was confirmed when the patients received 75 g lactose and were positive after 30 min until 3 hr for lactose intolerance symptoms and by hydrogen breath test (HBT). After intervention, the hydrogen level was lower in experimental group in comparison with the control group. Lactose intolerance symptoms in experimental group were much less than the control group. Our findings revealed that probiotic yogurt fortified with L. acidophilus and Bifidobacterium sp. could safely and effectively decrease lactose intolerance symptoms and HBT, so our probiotic can be recommended as a treatment of choice in lactose intolerance patients.

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