Structure-based epitope and PEGylation sites mapping of phenylalanine ammonia-lyase for enzyme substitution treatment of phenylketonuria

Molecular Genetics and Metabolism - Tập 91 - Trang 325-334 - 2007
Alejandra Gámez1, Lin Wang1, Christineh N. Sarkissian2, Dan Wendt3, Paul Fitzpatrick3, Jeffrey F. Lemontt3, Charles R. Scriver2, Raymond C. Stevens1
1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
2Departments of Biology, Human Genetics, and Pediatrics, McGill University, and DeBelle Laboratory, McGill University-Montreal Children’s Hospital Research Institute, 2300 Tupper Street, A-717, Montreal, Que., Canada H3H 1P3
3BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA 94949, USA

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Molecular Genetics and Metabolism

Tập 91

325-334

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