Role of Resolvins in the Inflammatory Resolution of Neurological Diseases

Albekairi, 2019, Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP), Pharmaceutics, 11, 467, 10.3390/pharmaceutics11090467

Andersson, 2008, Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis, J. Leukocyte Biol., 84, 1248, 10.1189/jlb.1207844

Banerjee, 2017, Role of Pro-Inflammatory Cytokines and Vitamin D in Probable Alzheimer’s Disease with Depression, Aging Dis., 8, 267, 10.14336/AD.2016.1017

Benabdoune, 2016, The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis, Inflammation Res., 65, 635, 10.1007/s00011-016-0946-x

Bento, 2011, Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice, J. Immunol. (Baltimore Md.: 1950), 187, 1957, 10.4049/jimmunol.1101305

Bisicchia, 2018, Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs, Mol. Neurobiol., 55, 6894, 10.1007/s12035-018-0889-z

Cassella, 2017, Ischemic Stroke: Advances in Diagnosis and Management, Emergency Med. Clinics North America, 35, 911, 10.1016/j.emc.2017.07.007

Celis-Plá, 2019, MAPK Pathway under Chronic Copper Excess in Green Macroalgae (Chlorophyta): Influence on Metal Exclusion/Extrusion Mechanisms and Photosynthesis, Int. J. Mol. Sci., 20, 4547, 10.3390/ijms20184547

Chen, 2017, TGF-β1 Neuroprotection via Inhibition of Microglial Activation in a Rat Model of Parkinson’s Disease, J. Neuroimmune Pharmacol., 12, 433, 10.1007/s11481-017-9732-y

Chen, 2018, Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain, Neuron, 100, 1292, 10.1016/j.neuron.2018.11.009

Chiang, 2015, Identification of resolvin D2 receptor mediating resolution of infections and organ protection, J. Exp. Med., 212, 1203, 10.1084/jem.20150225

Chiurchiù, 2016, Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses, Sci. Trans. Med., 8, 353ra111, 10.1126/scitranslmed.aaf7483

Chiurchiù, 2016, Is Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative Diseases, Oxid. Med. Cell. Longevity, 2016, 10.1155/2016/7909380

Chiurchiù, 2019, Resolution of inflammation is altered in chronic heart failure and entails a dysfunctional responsiveness of T lymphocytes, FASEB J., 33, 909, 10.1096/fj.201801017R

Colby, 2016, Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia, Am. J. Pathol., 186, 1801, 10.1016/j.ajpath.2016.03.011

Correale, 2017, Progressive multiple sclerosis: from pathogenic mechanisms to treatment, Brain, 140, 527, 10.1093/brain/aww258

Correale, 2017, Progressive multiple sclerosis: from pathogenic mechanisms to treatment, Brain, 140, 527, 10.1093/brain/aww258

da Cruz Moreira-Junior, 2019, Hyper-serotonergic state determines onset and progression of idiopathic Parkinson’s disease, Med. Hypotheses, 133, 10.1016/j.mehy.2019.109399

Das, 2012, Is multiple sclerosis a proresolution deficiency disorder, Nutr. (Burbank Los Angeles County Calif.), 28, 951, 10.1016/j.nut.2011.12.016

Dean, 2019, Aspirin Triggered Resolvin D1 reduces inflammation and restores saliva secretion in a Sjögren’s syndrome mouse model, Rheumatol. (Oxford England), 58, 1285, 10.1093/rheumatology/kez072

Deyama, 2017, Resolvin D1 and D2 Reverse Lipopolysaccharide-Induced Depression-Like Behaviors Through the mTORC1 Signaling Pathway, Int. J. Neuropsychopharmacol., 20, 575, 10.1093/ijnp/pyx023

Deyama, 2018, Resolvin E1/E2 ameliorate lipopolysaccharide-induced depression-like behaviors via ChemR23, Psychopharmacology, 235, 329, 10.1007/s00213-017-4774-7

Dyall, 2015, Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA, Front. Aging Neurosci., 7, 10.3389/fnagi.2015.00052

Easley, 2016, AT-RvD1 combined with DEX is highly effective in treating TNF-α-mediated disruption of the salivary gland epithelium, Physiol. Rep., 4, 10.14814/phy2.12990

El Kebir, 2012, Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation, Proc. Natl. Acad. Sci. U. S. A., 109, 14983, 10.1073/pnas.1206641109

Emre, 2020, Receptors for pro-resolving mediators are increased in Alzheimer’s disease brain, Brain Pathol. (Zurich Switzerland)., 10.1111/bpa.12812

Fiala, 2016, Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment, J. Alzheimer’s Dis., 49, 1191, 10.3233/JAD-159008

Flesher, 2014, Resolvin E1 promotes resolution of inflammation in a mouse model of an acute exacerbation of allergic asthma, Clin. Sci. (London Engl.: 1979), 126, 805, 10.1042/CS20130623

Fredman, 2017, Specialized pro-resolving mediators in cardiovascular diseases, Mol. Aspects Med., 58, 65, 10.1016/j.mam.2017.02.003

Fredman, 2012, Self-limitedv delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA, Sci Rep., 2, 639, 10.1038/srep00639

Fullerton, 2016, Resolution of inflammation: a new therapeutic frontier, Nat. Rev. Drug Discovery, 15, 551, 10.1038/nrd.2016.39

Gafson, 2018, Lipoprotein markers associated with disability from multiple sclerosis, Sci. Rep., 8, 17026, 10.1038/s41598-018-35232-7

Gilbert, 2015, Resolvin D1 Reduces Infarct Size Through a Phosphoinositide 3-Kinase/Protein Kinase B Mechanism, J. Cardiovasc. Pharmacol., 66, 72, 10.1097/FJC.0000000000000245

Gilligan, 2019, Aspirin-triggered proresolving mediators stimulate resolution in cancer, Proc. Natl. Acad. Sci. U. S. A., 116, 6292, 10.1073/pnas.1804000116

Hamlett, 2020, RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome, Glia., 10.1002/glia.23779

Ho, 2010, Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis, Am. J. Pathol., 177, 2116, 10.2353/ajpath.2010.091082

Huang, 2020, Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery, Int. J. Mol. Sci., 21, 739, 10.3390/ijms21030739

Ishida, 2010, Resolvin E1, an endogenous lipid mediator derived from Eicosapentaenoic Acid, prevents Dextran Sulfate Sodium-Induced Colitis, Inflamm. Bowel Dis., 16, 87, 10.1002/ibd.21029

Jiang, 2017, Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats, Front. Mol. Neurosci., 10, 10.3389/fnmol.2017.00363

Jin, 2018, Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21, Ann. Rheumatic Dis., 77, 1644, 10.1136/annrheumdis-2018-213511

Joffre, 2019, N-3 Polyunsaturated Fatty Acids and the Resolution of Neuroinflammation, Front. Pharmacol., 10, 10.3389/fphar.2019.01022

Jung, 2014, Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells, Mol. Cell. Endocrinol., 391, 30, 10.1016/j.mce.2014.04.012

Kantarci, 2018, Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer’s disease, Exp. Neurol., 300, 111, 10.1016/j.expneurol.2017.11.005

Kaye, 2019, Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells, Exp. Eye Res., 180, 53, 10.1016/j.exer.2018.11.018

Keyes, 2010, Resolvin E1 protects the rat heart against reperfusion injury. American journal of physiology, Heart Circulatory Physiol., 299, H153, 10.1152/ajpheart.01057.2009

Krashia, 2019, Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease, Nat. Commun., 10, 3945, 10.1038/s41467-019-11928-w

Langert, 2017, Attenuation of experimental autoimmune neuritis with locally administered lovastatin-encapsulating poly(lactic-co-glycolic) acid nanoparticles, J. Neurochem., 140, 334, 10.1111/jnc.13892

Leuti, 2019, Proresolving Lipid Mediators: Endogenous Modulators of Oxidative Stress, Oxid. Med. Cell. Longevity, 2019, 10.1155/2019/8107265

Linton, 2016, Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis, Circ. J., 80, 2259, 10.1253/circj.CJ-16-0924

Liu, 2012, Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1, Am. J. Neurodegenerative Dis., 1, 60

Liu, 2019, HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis, Proc. Natl. Acad. Sci. U. S. A., 116, 23254, 10.1073/pnas.1907490116

Luo, 2016, Resolvin D1 Programs Inflammation Resolution by Increasing TGF-β Expression Induced by Dying Cell Clearance in Experimental Autoimmune Neuritis, J. Neurosci., 36, 9590, 10.1523/JNEUROSCI.0020-16.2016

Marcheselli, 2003, Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression, J. Biol. Chem., 278, 43807, 10.1074/jbc.M305841200

Mitchell, 2002, Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo, J. Am. Soc. Nephrol., 13, 2497, 10.1097/01.ASN.0000032417.73640.72

Miyahara, 2013, D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury, FASEB J., 27, 2220, 10.1096/fj.12-225615

Mizwicki, 2013, 1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer’s disease patients, J. Alzheimer’s Dis., 34, 155, 10.3233/JAD-121735

Newcombe, 2018, Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease, J. Neuroinflammation, 15, 276, 10.1186/s12974-018-1313-3

Oehler, 2017, Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats, Front. Mol. Neurosci., 10, 10.3389/fnmol.2017.00242

Ohira, 2010, Resolvin E1 receptor activation signals phosphorylation and phagocytosis, J. Biol. Chem., 285, 3451, 10.1074/jbc.M109.044131

Ontaneda, 2017, Progressive multiple sclerosis: prospects for disease therapy, repair, and restoration of function, Lancet, 389, 1357, 10.1016/s0140-6736(16)31320-4

Ostermann, 2019, Plasma oxylipins respond in a linear dose-response manner with increased intake of EPA and DHA: results from a randomized controlled trial in healthy humans, Am. J. Clin. Nutr., 109, 1251, 10.1093/ajcn/nqz016

Pillai, 2012, Chemical mediators of inflammation and resolution in post-operative abdominal aortic aneurysm patients, Inflammation, 35, 98, 10.1007/s10753-011-9294-8

Pirault, 2018, Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease, Front. Pharmacol., 9, 10.3389/fphar.2018.01273

Poisson, 2015, Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis, J. Biol. Chem., 290, 30697, 10.1074/jbc.M115.679068

Pruss, 2013, Proresolution lipid mediators in multiple sclerosis - differential, disease severity-dependent synthesis - a clinical pilot trial, PloS One, 8, 10.1371/journal.pone.0055859

Raj, 2017, Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain, Front. Mol. Neurosci., 10, 10.3389/fnmol.2017.00206

Refolo, 2019, Neuroinflammation and Glial Phenotypic Changes in Alpha-Synucleinopathies, Front. Cell. Neurosci., 13, 10.3389/fncel.2019.00263

Reinhold, 2017, Barrier function in the peripheral and central nervous system-a review, Pflugers Archiv., 469, 123, 10.1007/s00424-016-1920-8

Sato, 2019, Resolvin E3 attenuates allergic airway inflammation the interleukin-23-interleukin-17A pathway, FASEB J., 33, 12750, 10.1096/fj.201900283R

Serhan, 2018, Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators, J. Clin. Invest., 128, 2657, 10.1172/JCI97943

Serhan, 2015, Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome, Biochim. Biophys. Acta, 1851, 397, 10.1016/j.bbalip.2014.08.006

Serhan, 2018, Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids, J. Immunol. (Baltimore Md. 1950), 201, 3161, 10.4049/jimmunol.1800806

Serhan, 2019, Novel mediators and mechanisms in the resolution of infectious inflammation: evidence for vagus regulation, J. Internal Med., 286, 240, 10.1111/joim.12871

Shang, 2019, Inflammation resolution and specialized pro-resolving lipid mediators in CNS diseases, Expert Opin. Ther. Targets, 23, 967, 10.1080/14728222.2019.1691525

Shi, 2018, Treatment of Guillain-Barré syndrome with Bifidobacterium infantis through regulation of T helper cells subsets, Int. Immunopharmacol., 61, 290, 10.1016/j.intimp.2018.06.015

Sun, 2019, Exogenous hydrogen sulfide prevents lipopolysaccharide-induced inflammation by blocking the TLR4/NF-κB pathway in MAC-T cells, Gene, 710, 114, 10.1016/j.gene.2019.05.033

Tanaka, 2018, Eicosapentaenoic Acid-Enriched High-Density Lipoproteins Exhibit Anti-Atherogenic Properties, Circ. J., 82, 596, 10.1253/circj.CJ-17-0294

Taylor, 2015, Resolvin D1: A New Path to Unleash the Analgesic Potential of Peroxisome Proliferator-activated Receptor-γ for Postoperative Pain in Patients with Diabetes, Anesthesiology, 123, 1231, 10.1097/ALN.0000000000000893

Tian, 2015, Resolvin D2 recovers neural injury by suppressing inflammatory mediators expression in lipopolysaccharide-induced Parkinson’s disease rat model, Biochem. Biophys. Res. Commun., 460, 799, 10.1016/j.bbrc.2015.03.109

Tsuda, 2017, Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B pathway by high-density lipoprotein in macrophages, Sci. Rep., 7, 12989, 10.1038/s41598-017-13154-0

Valdes, 2017, Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans, Sci. Rep., 7, 10748, 10.1038/s41598-017-09516-3

Videla, 2019, Combined administration of docosahexaenoic acid and thyroid hormone synergistically enhances rat liver levels of resolvins RvD1 and RvD2, Prostaglandins Leukotrienes Essential Fatty Acids, 140, 42, 10.1016/j.plefa.2018.11.013

Wang, 2011, Resolvin D1 protects mice from LPS-induced acute lung injury, Pulmonary Pharmacol. Ther., 24, 434, 10.1016/j.pupt.2011.04.001

Wang, 2015, Resolution of inflammation is altered in Alzheimer’s disease, Alzheimer’s Dementia, 11, 40, 10.1016/j.jalz.2013.12.024

Wu, 2017, Resolution of vascular injury: Specialized lipid mediators and their evolving therapeutic implications, Mol. Aspects Med., 58, 72, 10.1016/j.mam.2017.07.005

Xu, 2019, Resolvin E1 Ameliorates Pulpitis by Suppressing Dental Pulp Fibroblast Activation in a Chemerin Receptor 23-dependent Manner, J. Endodontics, 45, 1126, 10.1016/j.joen.2019.05.005

Ye, 2016, Expression and cell distribution of leukotriene B4 receptor 1 in the rat brain cortex after experimental subarachnoid hemorrhage, Brain Res., 1652, 127, 10.1016/j.brainres.2016.10.006

Yuan, 2019, Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases, Nat. Rev. Neurosci., 20, 19, 10.1038/s41583-018-0093-1

Zhang, 2013, Th1/Th2/Th17/Treg cytokines in Guillain-Barré syndrome and experimental autoimmune neuritis, Cytokine Growth Factor Rev., 24, 443, 10.1016/j.cytogfr.2013.05.005

Zhang, 2016, Resolvin D2 Enhances Postischemic Revascularization While Resolving Inflammation, Circulation, 134, 666, 10.1161/CIRCULATIONAHA.116.021894

Zhang, 2018, Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice, Front. Pharmacol., 9, 10.3389/fphar.2018.00412

Zhang, 2019, Intravenous immunoglobulin promotes the proliferation of CD4(+)CD25(+) Foxp3(+) regulatory T cells and the cytokines secretion in patients with Guillain-Barré syndrome in vitro, J. Neuroimmunol., 336, 577042, 10.1016/j.jneuroim.2019.577042

Zhu, 2016, Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis, Mol. Neurobiol., 53, 2733, 10.1007/s12035-015-9544-0

Zuo, 2018, Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats, Mol. Brain, 11, 9, 10.1186/s13041-018-0351-1