Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH

Cytogenetic and Genome Research - Tập 68 Số 1-2 - Trang 45-48 - 1995
Fumiko Saito1, Shiro Sasaki2, A.B. Chepelinsky3, Kiyohide Fushimi2, Fumiaki Marumo2, Tatsuro Ikeuchi1
1Department of Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
2Second Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
3Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD (USA)

Tóm tắt

The human AQP2 (collecting duct water channel, aquaporin 2) gene encodes a 271 amino acid protein and is a member of the MIP (major intrinsic protein of lens fiber) gene family. Using two-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for AQP2 and MIP as probes, we found that both genes mapped closely within the human chromosome region 12q13.

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Cytogenetic and Genome Research

Tập 68 Số 1-2

45-48

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