Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

Molecular Therapy - Tập 25 - Trang 1900-1916 - 2017
David Olagnier1,2, Rassin R. Lababidi1,2,3, Samar Bel Hadj1, Alexandre Sze1,2, Yiliu Liu1,2, Sharadha Dayalan Naidu4, Matteo Ferrari5, Yuan Jiang1,2, Cindy Chiang6, Vladimir Beljanski7, Marie-Line Goulet1, Elena V. Knatko4, Albena T. Dinkova-Kostova4,8, John Hiscott5, Rongtuan Lin1,2,3
1Lady Davis Institute-Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada
2Division of Experimental Medicine, McGill University, Montreal, QC H4A 3J1, Canada
3Department of Microbiology/Immunology, McGill University, Montreal, QC, H3A 2B4, Canada
4Jacqui Wood Cancer Centre, Division of Cancer Research, School of Medicine, University of Dundee, Dundee DD1 9SY, UK
5Pasteur Laboratory, Istituto Pasteur-Fondazione Cenci Bolognetti, Rome 00161, Italy
6Department of Microbiology, University of Chicago, Chicago, IL 60637, USA
7NSU Cell Therapy Institute, Nova Southeastern University, Fort Lauderdale, FL 33314, USA
8Department of Pharmacology and Molecular Sciences and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore MD 21205, USA

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