Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

American Association for the Advancement of Science (AAAS) - Tập 9 Số 374 - 2017
Waseem Qasim1,2, Hong Zhan2, Sujith Samarasinghe1, Stuart Adams1, Persis Amrolia1,2, Sian Stafford2, Katie Butler2, Christine Rivat2, Gary Wright1, Kathy Somana1, Sara Ghorashian2, Danielle Pinner1, Gul Ahsan1, Kimberly Gilmour1, Giovanna Lucchini1, Sarah Inglott1, William Mifsud1, Robert Chiesa1, Karl S. Peggs3, Lucas Chan4, Farzin Farzaneh4, Adrian J. Thrasher2, Ajay Vora5, Martin Pulé3, Paul Veys2
1Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
2Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
3Cancer Institute, University College London, London, WC1E 6DD, UK
4Division of Cancer Studies, Department of Haematological Medicine, King’s College London, London SE5 9NU, UK.
5Sheffield Children’s Hospital, Sheffield S10 2TH, UK.

Tóm tắt

Universal gene-edited CAR19 T cells eliminate infant leukemia.

Từ khóa


Tài liệu tham khảo

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American Association for the Advancement of Science (AAAS)

Tập 9 Số 374

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