Ataxia after pontine stroke: Insights from pontocerebellar fibers in monkey

Annals of Neurology - Tập 55 Số 4 - Trang 585-589 - 2004
Jeremy D. Schmahmann1, Douglas L. Rosene2, Deepak Ν. Pandya2
1Department of Neurology, Massachusetts General Hospital and Harvard Medical School
2Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA

Tóm tắt

AbstractBasis pontis lacunes cause contralateral but rarely ipsilateral ataxia. We explored this phenomenon with isotope tract tracing in the rhesus monkey. Labeled pontocerebellar fibers cross midline and disperse widely in the opposite hemipons before coalescing in the brachium pontis. This anatomical arrangement suggests that small pontine strokes spare sufficient decussating pontocerebellar fibers to prevent ipsilateral dysmetria, and that ipsilateral dysmetria after large pontine stroke represents a disconnection syndrome.

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Annals of Neurology

Tập 55 Số 4

585-589

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