Genetic Evidence for an East Asian Origin of Domestic Dogs

American Association for the Advancement of Science (AAAS) - Tập 298 Số 5598 - Trang 1610-1613 - 2002
Peter Savolainen1, Ya‐Ping Zhang2, Jing Luo2, Joakim Lundeberg1, Thomas Leitner3
1Department of Biotechnology, Royal Institute of Technology (KTH), 10691 Stockholm, Sweden.
2Yunnan Laboratory of Molecular Biology of Domestic Animals, and Laboratory of Molecular Evolution and Genome Diversity, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
3Department of Virology, Swedish Institute for Infectious Disease Control, 17182 Solna, Sweden

Tóm tắt

The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, ∼15,000 years ago.

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This work was supported by the Swedish Research Council the Swedish Kennel Club the State Key Basic Research and Development Plan of China (G20000161) and Natural Sciences Foundation of China. We thank numerous contributors of samples especially J. Koler-Matznickand D. Selin for sampling coordination and L. Arvestad for help with calculations. mtDNA sequences have been deposited in GenBank (accession numbers to and to ).

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American Association for the Advancement of Science (AAAS)

Tập 298 Số 5598

1610-1613

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