Chlorhexidine Preserves Dentin Bond <i>in vitro</i>

SAGE Publications - Tập 86 Số 1 - Trang 90-94 - 2007
Marcela Rocha de Oliveira Carrilho1,2,3,4,5, Ricardo M. Carvalho1,2,3,4,5, Mário Fernando de Góes1,2,3,4,5, Vinícius Di Hipólito1,2,3,4,5, Saulo Geraldeli1,2,3,4,5, Franklin R. Tay1,2,3,4,5, D.H. Pashley1,2,3,4,5, Leo Tjäderhane1,2,3,4,5
1Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GA, USA; and
2Department of Prosthodontics, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil;
3Department of Restorative Dentistry, Dental Materials, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil
4Dows Institute for Dental Research and Department of Operative Dentistry, University of Iowa, Iowa City, USA;
5Institute of Dentistry, University of Helsinki, PO Box 41, 00014 University of Helsinki, and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki, Finland

Tóm tắt

Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted third molars were sectioned into two halves. One half was customarily restored (etch-and-rinse adhesive/resin composite), and the other was treated with 2% chlorhexidine after being acid-etched before restoration. Specimens were stored in artificial saliva with/without protease inhibitors. Microtensile bond strengths and failure mode distribution under SEM were analyzed immediately after specimens’ preparation and 6 months later. With chlorhexidine, significantly better preservation of bond strength was observed after 6 months; protease inhibitors in the storage medium had no effect. Failure analysis showed significantly less failure in the hybrid layer with chlorhexidine, compared with controls after 6 months. In conclusion, this in vitro study suggests that chlorhexidine might be useful for the preservation of dentin bond strength.

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Tài liệu tham khảo

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SAGE Publications

Tập 86 Số 1

90-94

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