Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends

International Journal of Endocrinology - Tập 2011 - Trang 1-7 - 2011
P. V. Pradeep1, B. Jayashree1, Anjali Mishra2, Saroj Kanta Mishra2
1Narayana Medical College and Superspeciality Hospitals, Nellore, Andhra Pradesh, India.
2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Tóm tắt

Primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the Western world with the introduction of routine calcium screening. However, the same phenomenon is not observed in India. We have now systematically reviewed the status of PHPT in India. While there is a paucity of literature on PHPT from India when compared to Western countries, some information can be gleaned upon. Most patients present with symptomatic disease whereas very few are screen-detected cases (bone disease 77%, renal disease 36%, and 5.6% asymptomatic). Mean calcium, parathyroid hormone (PTH), and alkaline phosphate levels are high while Vitamin D levels are low. The average parathyroid gland weight is large and the majority being parathyroid adenomas (89.1%). Hungry bone syndrome (HBS) is common in the postoperative period. The disease-related mortality rate is 7.4%, recurrence 4.16%, and persistent disease 2.17%. We suggest that dedicated efforts are needed to pick up asymptomatic disease in India by methods like incorporating calcium estimation in the routine health check-up programs.

Từ khóa


Tài liệu tham khảo

2005, Endocrine Practice, 11, 50

10.1056/NEJMcp032200

2001, Diagnosis, natural history and intervention in sporadic primary hyperparathyroidism, 137

10.1046/j.0007-1323.2001.01775.x

10.1007/s00268-007-9384-9

2005, Annals of Saudi Medicine, 25, 29, 10.5144/0256-4947.2005.29

10.1136/pgmj.2007.062653

10.1111/j.1445-2197.2006.03845.x

1995, Clinical Endocrinology, 43, 351, 10.1111/j.1365-2265.1995.tb02043.x

10.1007/s00268-005-0366-5

1980, Indian Journal of Cancer, 17, 164

2010, Journal of Postgraduate Medicine, 56, 79, 10.4103/0022-3859.65279

1985, The Indian Journal of Medical Research, 81, 607

10.1016/j.suc.2004.01.004

10.1210/jc.2008-1762

10.4103/0377-4929.54983

10.1111/j.1365-2265.2006.02601.x

1994, Indian Journal of Cancer, 31, 72

1994, Journal of Paediatrics and Child Health, 30, 441, 10.1111/j.1440-1754.1994.tb00698.x

2002, Indian Pediatrics, 39, 1044

2001, Indian Journal of Medical Sciences, 55, 677

2009, Clinical Endocrinology, 70, 527, 10.1111/j.1365-2265.2008.03346.x

1993, The Journal of the Association of Physicians of India, 41, 533

1990, The Journal of the Association of Physicians of India, 38, 154

2005, Indian Journal of Radiology and Imaging, 15, 485, 10.4103/0971-3026.28780

2008, Journal of Pediatric Endocrinology and Metabolism, 21, 1147

1999, Journal of the Pakistan Medical Association, 49, 194

2003, Saudi Medical Journal, 24, 179

2000, Turkish Journal of Endocrinology and Metabolism, 4, 139

2003, Saudi Medical Journal, 24, 1214

1998, Hongkong Medical Journal, 4, 229

2006, Medical Science Monitor, 12, CR86

2010, Endocrine Practice, 6, 1

1997, Chinese Medical Journal, 110, 612

2003, Israel Medical Association Journal, 5, 326

1986, South African Medical Journal, 69, 94

10.1001/archsurg.139.1.77

10.1007/s00268-009-0044-0

2003, Indian Journal of Gastroenterology, 22, 224

2003, Journal of Association of Physicians of India, 51, 68

Thông tin
Thông tin xuất bản

International Journal of Endocrinology

Tập 2011

1-7

Thông tin tác giả