Effects of care pathways on the in-hospital treatment of heart failure: a systematic review

BMC Cardiovascular Disorders - Tập 12 - Trang 1-9 - 2012
Seval Kul1, Antonella Barbieri2, Erika Milan3, Ilke Montag4, Kris Vanhaecht4,5, Massimiliano Panella2,5
1Department of Biostatistics, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey
2Department of Clinical and Experimental Medicine, University of Eastern Piedmont 'A. Avogadro', Novara, Italy
3Santa Rita Hospital, Vercelli, Italy
4Center for Health Services and Nursing Research, School of Public Health, Catholic University, Leuven, Belgium
5European Pathway Association, Leuven, Belgium

Tóm tắt

Care pathways have become a popular tool to enhance the quality of care by improving patient outcomes, promoting patient safety, increasing patient satisfaction, and optimizing the use of resources. We performed a disease specific systematic review to determine how care pathways in the hospital treatment of heart failure affect in-hospital mortality, length of in-hospital stay, readmission rate and hospitalisation cost when compared with standard care. Medline, Cinahl, Embase and the Cochrane Central Register of Controlled Trials were searched from 1985 to 2010. Each study was assessed independently by two reviewers. Methodological quality of the included studies was assed using the Jadad methodological approach for randomised controlled trials, controlled clinical trials and the New Castle Ottawa Scale for case–control studies, cohort studies and time interrupted series. Seven studies met the study inclusion criteria and were included in the systematic review with a total sample of 3,690 patients. The combined overall results showed that care pathways have a significant positive effect on mortality and readmission rate. A shorter length of hospital stay was also observed compared with the standard care group. No significant difference was found in the hospitalisation costs. More positive results were observed in controlled trials compared to randomized controlled trials. By combining all possible results, it can be concluded that care pathways for treatment of heart failure decrease mortality rates and length of hospital stay, but no statistically significant difference was observed in the readmission rates and hospitalisation costs. However, one should be cautious with overall conclusions: what works for one organization may not work for another because of the subtle differences in processes and bottlenecks.

Tài liệu tham khảo

Mcghee G, Murphy E: Research on Reducing Hospitalizations in Patients with Chronic Heart Failure. Home Healthc Nurse. 2010, 28: 331-340. 10.1097/NHH.0b013e3181df5e09. Cowie MR, Fox KF, Wood DA, Metcalfe C, Thompson SG, Coats AJ, Poole-Wilson PA, Sutton GC: Hospitalization of patients with heart failure. A population-based study. Eur Hearth J. 2002, 11: 877-885. American Heart Association: Heart Disease and Stroke Statistics: 2010 Update. A Report from the American Heart Association Statistics Committee and Stroke Statistics. 2009, 10.1161/CIRCULATIONAHA.109.192667. Published online ahead of print 17 Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brow M: Projections of the cost of cancer care in the United States 2010–2020. J Natl Cancer Inst. 2011, 103: 117-128. 10.1093/jnci/djq495. Panella M, Marchisio S, Di Stanislao F: Reducing clinical variations with care pathways: do pathways work?. Int J Qual Health Care. 2003, 15: 509-521. 10.1093/intqhc/mzg057. Pearson SD, Goulart-Fisher D, Lee TH: Critical pathways as a strategy for improving care: problems and potential. Ann Intern Med. 1995, 12: 941-948. Vanhaecht K, De Witte K, Sermeus W: The impact of care pathways on the organisation of care processes. 2007, Leuven: ACCO Vanhaecht K, Panella M, Sermeus ZR, Sermeus W: An overview on the history and concept of care pathways as complex interventions. Intl J Care Pathw. 2010, 14: 117-123. 10.1258/jicp.2010.010019. Lougheed MD, Olajos-Clow JG: Asthma care pathways in the emergency department. Curr Opin Allergy Clin Immunol. 2010, 10 (3): 181-187. 10.1097/ACI.0b013e328339731d. Panella M, Marchisio S, Demarchi ML, Manzoli L, Stanislao FD: Reduced in-hospital mortality for heart failure with care pathways: the results of a cluster randomised controlled trial. Qual Saf Health Care. 2009, 18: 369-373. 10.1136/qshc.2008.026559. Ski CF, Thompson DR: Beyond the blues: the need for integrated care pathways. Eur J Cardiovasc Prev Rehabil. 2011, 18 (2): 218-221. 10.1177/1741826710389409. Evans-Lacko S, Jarrett M, McCrone P, Thornicroft G: Facilitators and barriers to implementing clinical care pathways. BMC Health Serv Res. 2010, 28 (10): 182- Khandaker GM, Gandamaneni PK, Dibben CR, Cherukuru S, Cairns P, Ray MK: Evaluating care pathways for community psychiatry in England: a qualitative study. J Eval Clin Pract. 2012, 10.1111/j.1365-2753.2012.01822.x. [Epub ahead of print] Barbieri A, Vanhaecht K, Van Herck HP, Sermeus W, Faggiano F, Marchisio S, Panella M: Effects of care pathways in the joint replacement: a meta-analysis. BMC Med. 2009, 7: 32-10.1186/1741-7015-7-32. Neuman MD, Archan S, Karlawish JH, Schwartz JS, Fleisher LA: The relationship between short-term mortality and quality of care for hip fracture: a meta-analysis of care pathways for hip fracture. J Am Geriatr Soc. 2009, 57 (11): 2046-54. 10.1111/j.1532-5415.2009.02492.x. Van Herck P, Vanhaecht K, Deneckere S, Bellemans J, Panella M, Barbieri A, Sermeus W: Key interventions and outcomes in joint arthroplasty care pathways: a systematic review. J Eval Clin Pract. 2010, 16 (1): 39-49. 10.1111/j.1365-2753.2008.01111.x. Renholm M, Leino-Kilpi H, Suominen T: Critical pathways. A systematic review. J Nurs Adm. 2002, 32 (4): 196-202. 10.1097/00005110-200204000-00008. Rotter T, Kugler J, Koch R, Gothe H, Twork S, van Oostrum JM, Steyerberg EW: A systematic review and meta-analysis of the effects of care pathways on length of stay, hospital costs and patient outcomes. BMC Health Serv Res. 2008, 8: 265-10.1186/1472-6963-8-265. Rotter T, Kinsman L, James E, Machotta A, Gothe H, Willis J, Snow P, Kugler J: Care pathways: effects on professional practice, patient outcomes, length of stay and hospital costs. Cochrane Database Syst Rev. 2010, 17 (3): CD006632- Zander K: Integrated care pathways: eleven international trends. J Integr Care Pathways. 2002, 6: 101-107. Cardozo L, Aherns S: Assessing the efficacy of a care pathway in the management of older patients hospitalized with congestive heart failure. J Health Qual. 1999, 21 (3): 12-6. 10.1111/j.1945-1474.1999.tb00958.x. Philbin E, Thomas AR, Lindenmuth NW, Ulrich K, McCall M, Jenkins PL: The results of a randomized trial of quality improvement intervention in the care of patients with heart failure. Am J Med. 2000, 109: 443-449. 10.1016/S0002-9343(00)00544-1. Azad N, Molnar F, Byszewski A: Lessons learned from a multidisciplinary heart failure clinic for older women: a randomised controlled trial. Age Ageing. 2008, 37: 282-287. 10.1093/ageing/afn013. Lannone P, Lenzi T: Effectiveness of a multipurpose observation unit: before and after study. Emerg Med J. 2009, 26: 407-414. 10.1136/emj.2007.057539. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ: Assessing the quality of randomized trials: is blinding necessary. Control Clin Trials. 1996, 17: 1-12. 10.1016/0197-2456(95)00134-4. Higgins JPT, Green S: ochrane Handbook for Systematic Reviews of Interventions 4.2.5. 2005, Chichester, UK: John Wiley & Sons, Ltd: The Cochrane Library Higgins JP, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in meta-analyses. BMJ. 2003, 327: 557-560. 10.1136/bmj.327.7414.557. Discher CL, Klein D, Pierce L, Levine AB, Levine TB: Heart failure disease management: impact on hospital care, length of stay, and reimbursement. Congest Heart Fail. 2003, 9 (2): 77-83. 10.1111/j.1527-5299.2003.01461.x. Lanzieri M, Hobbs R, Roy P, Richmond R: Use of a clinical care map for the management of congestive heart failure in a community hospital. Clinical Care Map. 2001, 7: 37-42. Rauh RA, Schwabauer RN, Enger EL, Moran JF: A Community hospital-based congestive hearth failure program: Impact on length of stay, admission and readmission rates and cost. Am J Manag Care. 1999, 5: 37-43. Vanhaecht K, Ovretveit J, Elliott MJ, Sermeus W, Ellershaw JE, Panella M: Have we drawn the wrong conclusions about the value of care pathways? Is a cochrane review appropriate?. Evaluation & the Health Professional. 2011, 35 (1): 28-42. Panella M, Vanhaecht K: Care pathways and organizational systems: the basis for a successful connection. Int J Care Pathways. 2010, 15: 45-46. Petiti DB: Approaches to heterogeneity in meta analysis. Statist Med. 2001, 20: 3625-3633. 10.1002/sim.1091. Higgins JPT: Commentary: Heterogeneity in meta-analysis International should be expected and appropriately quantified. J Epidemiol. 2008, 37: 1158-1160. 10.1093/ije/dyn204. Patsopoulos NA, Evangelou E, Ioannidis JPA: Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol. 2008, 37: 1148-57. 10.1093/ije/dyn065. De Bleser L, Depreitere R, Waele KD, Vanhaecht K, Vlayen J, Sermeus W: Defining pathways. J Nurs Manag. 2006, 14 (7): 553-563. 10.1111/j.1365-2934.2006.00702.x. Kinsman L, Rotter T, James E, Snow P, Willis J: What is a care pathway? Development of a definition to inform the debate. BMC Med. 2010, 8: 31-10.1186/1741-7015-8-31. Vanhaecht K: Care Pathways are defined as complex interventions. http://www.biomedcentral.com/1741-7015/8/31/comments (10 October 2012) Vanhaecht K, De Witte K, Depreitere R, Sermeus W: Care pathway audit tools: a systematic review. J Nurs Manag. 2006, 14 (7): 529-537. 10.1111/j.1365-2934.2006.00705.x. Goldmann D: Five puzzle pieces, ten cautionary notes. Int J Care Pathways. 2010, 14 (1): 33-35. 10.1258/jicp.2010.010002. Hawe P, Shiell A, Riley T, Gold L: Methods for exploring implementation variation and local context within a cluster randomised community intervention trial. J Epidemiol Community Health. 2004, 58 (9): 788-793. 10.1136/jech.2003.014415. Berwick DM: The science of ımprovement. JAMA. 2008, 299 (10): 1182-1184. 10.1001/jama.299.10.1182. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2261/12/81/prepub