Omental Leiomyoma in a Male Adult Horse

Veterinary Pathology - Tập 44 Số 5 - Trang 722-726 - 2007
Dirk Schaudien1, J. Müller2, Wolfgang Baumgärtner1
1Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany (DS, WB)
2Equine Clinic, University of Veterinary Medicine Hannover, Hannover, Germany (JMVM)

Tóm tắt

A well-circumscribed mass 70 X 35 X 28 cm in size and 41 kg in weight was detected at necropsy in a male adult horse within the omentum major without any association to the gastrointestinal tract. The tumor consisted of multiple white-to-yellow lobules and displayed a firm consistency. In addition, multiple cysts filled with blood-like fluid, and multifocal areas of necrosis were observed. Histologically, the mass consisted of slightly pleomorphic spindloid-shaped cells arranged in interlacing bundles containing elongated nuclei with blunt ends. The majority of tumor cells revealed a positive immunoreaction for α-smooth muscle actin, vimentin, and neuron-specific enolase and were negative for S-100, factor VIII-related antigen, and glial fibrillary acidic protein. Few tumor cells showed expression of desmin and c-kit. On the basis of macroscopy, histology, and immunohistochemistry, an omental leiomyoma was diagnosed.

Từ khóa


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