CTSB promotes porcine preadipocytes differentiation by degrading fibronectin and attenuating the Wnt/β-catenin signaling pathway

Bulcao C, Ferreira SR, Giuffrida F, Ribeiro-Filho FF (2006) The new adipose tissue and adipocytokines. Curr Diabetes Rev 2:19–28 Gandhi H, Upaganlawar A, Balaraman R (2010) Adipocytokines: the pied pipers. J Pharmacol Pharmacother 1:9–17 Krysiak R, Okopień B, Herman ZS (2005) Adipose tissue: a new endocrine organ. Przegl Lek 62:919–923 Chun T-H (2012) Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis. Adipocyte 1:89–95 Hirsch J, Batchelor B (1976) Adipose tissue cellularity in human obesity. Clin Endocrinol Metab 5:299–311 Gregor MF, Hotamisligil GS (2011) Inflammatory mechanisms in obesity. Annu Rev Immunol 29:415–445 Lumeng CN, Saltiel AR (2011) Inflammatory links between obesity and metabolic disease. J Clin Invest 121:2111 Schenk S, Saberi M, Olefsky JM (2008) Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 118:2992–3002 Nakajima I, Muroya S, Tanabe R-I, Chikuni K (2002) Extracellular matrix development during differentiation into adipocytes with a unique increase in type V and VI collagen. Biol Cell 94:197–203 Antras J, Hilliou F, Redziniak G, Pairault J (1989) Decreased biosynthesis of actin and cellular fibronectin during adipose conversion of 3T3-F442A cells. Reorganization of the cytoarchitecture and extracellular matrix fibronectin. Biol Cell 66:247–254 Rodríguez Fernández JL, Ben-Ze’ev A (1989) Regulation of fibronectin, integrin and cytoskeleton expression in differentiating adipocytes: inhibition by extracellular matrix and polylysine. Differentiation 42:65–74 Spiegelman BM, Ginty CA (1983) Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes. Cell 35:657–666 Brix K, Dunkhorst A, Mayer K, Jordans S (2008) Cysteine cathepsins: cellular roadmap to different functions. Biochimie 90:194–207 Conus S, Simon H-U (2008) Cathepsins: key modulators of cell death and inflammatory responses. Biochem Pharmacol 76:1374–1382 Tardy C, Codogno P, Autefage H et al (2006) Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle). Biochim Biophys Acta 1765:101–125 Zava\vsnik-Bergant T, Turk B (2007) Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells. Biol Chem 388:1141–1149 Chavey C, Mari B, Monthouel M-N et al (2003) Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J Biol Chem 278:11888–11896 Taleb S, Lacasa D, Bastard J-P et al (2005) Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis. FASEB J 19:1540–1542 Taleb S, Cancello R, Clément K, Lacasa D (2006) Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation. Endocrinology 147:4950–4959 Masson O, Prébois C, Derocq D et al (2011) Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis. PLoS One 6:e16452 Chiellini C, Costa M, Novelli SE et al (2003) Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J Cell Physiol 195:309–321 Funicello M, Novelli M, Ragni M et al (2007) Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores. PLoS One 2:e683 Withana NP, Blum G, Sameni M et al (2012) Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res 72:1199–1209 Cavallo-Medved D, Rudy D, Blum G et al (2009) Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation. Exp Cell Res 315:1234–1246 Wong WP, Altemus JB, Hester JF et al (2013) Cathepsin B is a novel gender-dependent determinant of cholesterol absorption from the intestine. J Lipid Res 54:816–822 Morchang A, Panaampon J, Suttitheptumrong A et al (2013) Role of cathepsin B in dengue virus-mediated apoptosis. Biochem Biophys Res Commun 438:20–25 Tatti M, Motta M, Di Bartolomeo S et al (2013) Cathepsin-mediated regulation of autophagy in saposin C deficiency. Autophagy 9:241–243 Freese JL, Pino D, Pleasure SJ (2010) Wnt signaling in development and disease. Neurobiol Dis 38:148–153 Lefterova MI, Lazar MA (2009) New developments in adipogenesis. Trends Endocrinol Metab 20:107–114 Rosen ED, MacDougald OA (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7:885–896 He XC, Zhang J, Tong W-G et al (2004) BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling. Nat Genet 36:1117–1121 Logan CY, Nusse R (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781–810 Luo J, Deng Z-L, Luo X et al (2007) A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc 2:1236–1247 De Langhe SP, Sala FG, Del Moral P-M et al (2005) Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev Biol 277:316–331 Ten Berge D, Koole W, Fuerer C et al (2008) Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3:508–518 Eguchi A, Feldstein AE (2013) Lysosomal Cathepsin D contributes to cell death during adipocyte hypertrophy. Adipocyte 2:0–1 Naour N, Rouault C, Fellahi S et al (2010) Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation. J Clin Endocrinol Metab 95:1861–1868 Xiao Y, Junfeng H, Tianhong L et al (2006) Cathepsin K in adipocyte differentiation and its potential role in the pathogenesis of obesity. J Clin Endocrinol Metab 91:4520–4527 Yang M, Zhang Y, Pan J et al (2007) Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol 9:970–977 Li S, Du L, Zhang L et al (2013) Cathepsin B contributes to autophagy-related 7 (Atg7)-induced nod-like receptor 3 (NLRP3)-dependent proinflammatory response and aggravates lipotoxicity in rat insulinoma cell line. J Biol Chem 288:30094–30104 Santoni M, Amantini C, Morelli MB, et al (2013) Effect of sunitinib and pazopanib on necrosis and autophagic cell death in cancer cells: role of cathepsin B. J Clin Oncol. Abstr. p e15513 Li XJ, Yang H, Li GX et al (2012) Transcriptome profile analysis of porcine adipose tissue by high-throughput sequencing. Anim Genet 43:144–152 Gregoire FM, Smas CM, Sul HS (1998) Understanding adipocyte differentiation. Physiol Rev 78:783–809 Antras-Ferry J, Hilliou F, Lasnier F, Pairault J (1994) Forskolin induces the reorganization of extracellular matrix fibronectin and cytoarchitecture in 3T3-F442A adipocytes: its effect on fibronectin gene expression. Biochim Biophys Acta 1222:390–394 Bortell R, Owen TA, Ignotz R et al (1994) TGFβ1 prevents the down-regulation of type I procollagen, fibronectin, and TGFβ1 gene expression associated with 3T3-L1 pre-adipocyte differentiation. J Cell Biochem 54:256–263 Weiner FR, Shah A, Smith PJ et al (1989) Regulation of collagen gene expression in 3T3-L1 cells. Effects of adipocyte differentiation and tumor necrosis factor alpha. Biochemistry 28:4094–4099 Ross SE, Hemati N, Longo KA et al (2000) Inhibition of adipogenesis by Wnt signaling. Science 289:950–953 Vertino AM, Taylor-Jones JM, Longo KA et al (2005) Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell 16:2039–2048 Vangipuram SD, Sheele J, Atkinson RL et al (2004) A human adenovirus enhances preadipocyte differentiation. Obes Res 12:770–777 Wang Y, Zhao L, Smas C, Sul HS (2010) Pref-1 interacts with fibronectin to inhibit adipocyte differentiation. Mol Cell Biol 30:3480–3492