n–3 Fatty acid erythrocyte membrane content, APOE ε4, and cognitive variation: an observational follow-up study in late adulthood

The American Journal of Clinical Nutrition - Tập 87 Số 2 - Trang 449-454 - 2008
Lawrence J. Whalley1,2,3,4,5, Ian J. Deary1,2,3,4,5, John M. Starr1,2,3,4,5, Klaus Wahle1,2,3,4,5, K.A. Rance1,2,3,4,5, Victoria J. Bourne1,2,3,4,5, Helen Fox1,2,3,4,5
1From the Department of Environmental and Occupational Medicine, University of Aberdeen, Aberdeen, United Kingdom (LJW and HCF)
2Vascular Health, Rowett Research Institute, Aberdeen, United Kingdom (KAR)
3the Department of Life Sciences, Robert Gordon University, Aberdeen, United Kingdom (KWW)
4the Department of Psychology (IJD) and the Department of Geriatric Medicine, Royal Victoria Hospital (JMS), University of Edinburgh, Edinburgh, United Kingdom
5the Department of Psychology, University of Dundee, Dundee, United Kingdom (VJB)

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Gatz, 2006, Role of genes and environments for explaining Alzheimer disease., Arch Gen Psychiatry, 63, 168, 10.1001/archpsyc.63.2.168

Finkel, 2005, The longitudinal relationship between processing speed and cognitive ability: genetic and environmental influences., Behav Genet, 35, 535, 10.1007/s10519-005-3281-5

Cole, 2005, Prevention of Alzheimer's disease: omega-3 fatty acid and phenolic anti-oxidant interventions., Neurobiol Aging, 26, 133, 10.1016/j.neurobiolaging.2005.09.005

Luchsinger, 2004, Dietary factors and Alzheimer's disease., Lancet Neurol, 3, 579, 10.1016/S1474-4422(04)00878-6

Conquer, 2000, Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment., Lipids, 35, 1305, 10.1007/s11745-000-0646-3

Barberger-Gateau, 2002, Fish, meat, and risk of dementia: cohort study., BMJ, 325, 932, 10.1136/bmj.325.7370.932

Tully, 2003, Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study., Br J Nutr, 89, 483, 10.1079/BJN2002804

Morris, 2003, Consumption of fish and n–3 fatty acids and risk of incident Alzheimer disease., Arch Neurol, 60, 940, 10.1001/archneur.60.7.940

Morris, 2003, Dietary fats and the risk of incident Alzheimer disease., Arch Neurol, 60, 194, 10.1001/archneur.60.2.194

Heude, 2003, Cognitive decline and fatty acid composition of erythrocyte membranes—the EVA Study., Am J Clin Nutr, 77, 803, 10.1093/ajcn/77.4.803

Huang, 2005, Benefits of fatty fish on dementia risk are stronger for those without APOE epsilon4., Neurology, 65, 1409, 10.1212/01.wnl.0000183148.34197.2e

Whalley, 2004, Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n–3 fatty acids., Am J Clin Nutr, 80, 1650, 10.1093/ajcn/80.6.1650

Engelhart, 2002, Diet and risk of dementia: does fat matter? The Rotterdam Study., Neurology, 59, 1915, 10.1212/01.WNL.0000038345.77753.46

Laurin, 2003, Omega-3 fatty acids and risk of cognitive impairment and dementia., J Alzheimers Dis, 5, 315, 10.3233/JAD-2003-5407

Deary, 2002, Cognitive change and the APOE epsilon 4 allele., Nature, 418, 932, 10.1038/418932a

Corder, 1993, Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families., Science, 261, 921, 10.1126/science.8346443

Prince, 2000, The association between APOE and dementia does not seem to be mediated by vascular factors., Neurology, 54, 397, 10.1212/WNL.54.2.397

Deary, 2004, The impact of childhood intelligence on later life: following up the Scottish Mental Surveys of 1932 and 1947., J Pers Soc Psychol, 86, 130, 10.1037/0022-3514.86.1.130

Wenham, 1991, Apolipoprotein E genotyping by one-stage PCR., Lancet, 337, 1158, 10.1016/0140-6736(91)92823-K

Corder, 1994, Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease., Nat Genet, 7, 180, 10.1038/ng0694-180

Rapoport, 2003, In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism., J Pediatr, 143, S26, 10.1067/S0022-3476(03)00399-8

Song, 2004, Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease., Ann Intern Med, 141, 137, 10.7326/0003-4819-141-2-200407200-00013

Kivipelto, 2002, Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease., Ann Intern Med, 137, 149, 10.7326/0003-4819-137-3-200208060-00006

Serhan, 2002, Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals., J Exp Med, 196, 1025, 10.1084/jem.20020760

Kitajka, 2004, Effects of dietary omega-3 polyunsaturated fatty acids on brain gene expression., Proc Natl Acad Sci U S A, 101, 10931, 10.1073/pnas.0402342101

Minihane, 2000, ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype., Arterioscler Thromb Vasc Biol, 20, 1990, 10.1161/01.ATV.20.8.1990

Lim, 2006, Omega 3 fatty acid for the prevention of dementia., Cochrane Database Syst Rev, CD005379