Determinants of societal costs in Alzheimer's disease: GERAS study baseline results

Alzheimer's & Dementia - Tập 11 - Trang 933-945 - 2015
Richard Dodel1, Mark Belger2, Catherine Reed2, Anders Wimo3, Roy W. Jones4, Michael Happich2, Josep M. Argimon5, Giuseppe Bruno6, Bruno Vellas7, Josep Maria Haro8
1Department of Neurology, Philipps-University Marburg, Germany
2Eli Lilly and Company Limited, Lilly Research Centre, Windlesham, Surrey, UK
3Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden
4RICE - The Research Institute for the Care of Older People, The RICE Centre, Royal United Hospital, Bath, UK
5Agencia Qualitat i Avaluació Sanitaries, Barcelona, Spain
6Clinica della Memoria, Department of Neurological Sciences, University of Rome “Sapienza”, Rome, Italy
7Gerontopole, Alzheimer's Disease Research and Clinical Center, INSERM 1027, Toulouse University Hospital, Toulouse, France
8Parc Santari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain

Tóm tắt

AbstractBackgroundTo identify the main factors associated with societal costs of Alzheimer's disease (AD) in community‐dwelling patients across three European countries.MethodsBaseline cost data from a prospective, observational study were used. Assessments included patients' cognition, activities of daily living (ADLs) and behavioral symptoms, and caregiver burden. Cost calculations (2010) from the societal perspective were based on patient/caregiver resource use. Generalized linear models estimated factors associated with costs.ResultsMean monthly costs per patient differed for France (€1881), Germany (€2349), and the UK (€2016), with informal care costs accounting for 50% to 61%. Independent factors associated with costs across all countries were ADL total score, patient living arrangements, caregiver working status, and caregiver burden (all P < .05). Additional factors were significant for the pooled cohort or individual countries.ConclusionsSeveral patient and caregiver factors, including factors associated with informal care, should be included when evaluating care options for patients with AD.

Tài liệu tham khảo

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Alzheimer's & Dementia

Tập 11

933-945

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