Spermatogenesis in the rabbit following ligation of the epididymidis at different levels

Wiley - Tập 164 Số 3 - Trang 339-347 - 1969
S. Paufler1,2, R.H. Foote1,2
1Department of Animal Science Cornell University Ithaca, New York
2Tierärztliches Institut der Universität Göttingen, Germany

Tóm tắt

AbstractLigatures were placed unilaterally on the ductus deferens (experiment 1), on the ductus deferens and the middle of the corpus epididymidis (experiment 2) and on the ductus deferens, corpus epididymidis and ductuli efferentes (experiment 3) in 39 rabbits. The untreated contralateral side served as a control. Vasectomy alone appeared to have no effect upon the testes, or upon spermatozoa accumulated during a period of 12 weeks proximal to the ligature. In experiment 2 severe disruption of spermatogenesis occurred. Diameter of the seminiferous tubules decreased, testes atrophied, and the stages of the seminiferous epithelium were abnormal and often not classifiable. Some regeneration was observed after 12 weeks.In experiment 3 there was only a moderate and more transient disturbance of spermatogenesis. This occurred in spite of an accumulation of fluid in the testis due to the ligature on the ductuli efferentes, which prevented testicular effluent from reaching the caput epididymidis. These results suggest that when testicular effluent is allowed to reach the caput, but nonresorbed residues are prevented from further transport (experiment 2), a feedback to the testis occurs which is more harmful than that produced by preventing tubular contents from leaving the testes.

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Tài liệu tham khảo

10.1002/aja.1001100106

Baillie A. H., 1962, Observations comparing the effects of epididymal obstruction at various levels on the mouse testis with those of ischaemia, J. Anat., 96, 335

10.1530/jrf.0.0160035

Chalkley M. W., 1943, Method for the quantitative morphologic analysis of tissues, J. Nat. Cancer Inst., 4, 47

10.1677/joe.0.0230317

Harrison R. G., 1953, The effect of ligation of the vasa efferentia on the rat testis, Proc. Soc. Study Fert., 5, 97

Igboeli G.andR. H. Foote1969Maturation and aging changes in rabbit spermatozoa isolated by ligatures at different levels of the epididymis. Fertil. & Steril. In press.

10.1111/j.1749-6632.1952.tb26578.x

10.1002/aja.1000340203

Nicander L., 1963, Resorption phenomena in the epididymis, Int. J. Fertil., 8, 866

10.1530/jrf.0.0150015

10.1002/ar.1090740308

10.1530/jrf.0.0050309

10.1530/jrf.0.0070013

10.1007/BF00375645

10.1098/rspb.1933.0066

10.1007/BF00584422

Thông tin
Thông tin xuất bản

Wiley

Tập 164 Số 3

339-347

Thông tin tác giả