Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites

Brain Research - Tập 376 - Trang 97-107 - 1986
D. Hoyer1, A. Pazos1, A. Probst2, J.M. Palacios1
1Preclinical Research, Sandoz Ltd., CH-4002 Basle, Switzerland
2Department of Pathology, University of Basle, CH-4003 Basle, Switzerland

Tài liệu tham khảo

Aghajanian, 1981, The modulatory role of serotonin at multiple receptors in brain, 156 Bowen, 1983, Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease, J. Neurochem., 41, 266, 10.1111/j.1471-4159.1983.tb11838.x Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 248, 10.1016/0003-2697(76)90527-3 Closse, 1983, [3H]Mesulergine, a selective ligand for serotonin-2 receptors, Life Sci., 32, 2485, 10.1016/0024-3205(83)90375-2 Colpaert, 1983, The head-twitch response to intraperitoneal injections of 5-hydroxytryptophan in the rat: antagonistic effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD antagonist, Neuropharmacology, 22, 993, 10.1016/0028-3908(83)90215-0 Cortés, 1984, Visualization of multiple serotonin receptors in the rat brain by autoradiography, Br. J. Pharmacol., 82, 202P Cortés, 1984, Quantitative light microscopic autoradiographic localization of cholinergic muscarinic receptors in the human brain: brainstem, Neuroscience, 12, 1003, 10.1016/0306-4522(84)90001-0 Cross, 1984, Serotonin receptor changes in dementia of the Alzheimer type, J. Neurochem., 43, 1574, 10.1111/j.1471-4159.1984.tb06081.x Crow, 1984, Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia, depression and suicides, Neuropharmacology, 23, 1561, 10.1016/0028-3908(84)90100-X Dawson, 1967 De Lean, 1980, A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor, J. Biol. Chem., 255, 7108, 10.1016/S0021-9258(20)79672-9 Engel, 1983, Evidence for common pharmacological properties of [3H]5-hydroxytryptamine binding sitesm presynaptic 5-hydroxytryptamine autoreceptor in CNS and inhibitory presynaptic 5-hydroxytryptamine receptors on sympathetic nerves, Naunyn-Schmiedeberg's Arch. Pharmacol., 324, 116, 10.1007/BF00497016 Engel, 1980, Radioreceptor assay for the determination of beta-adrenoceptor blocking agents in blood and brain of rats, Experientia, 36, 706 Euvrard, 1980, Biochemical assessment of the central 5-HT agonist activity of RU 24969 (a piperidinyl indole), Eur. J. Pharmacol., 63, 65, 10.1016/0014-2999(80)90117-X Gozlan, 1983, Identification of presynaptic serotonin autoreceptors using a new ligand:3H-PAT, Nature (London), 305, 140, 10.1038/305140a0 Green, 1983, Inhibition of 5-hydroxytryptamine-mediated behavior by the putative 5-HT2 antagonist pirenperone, Neuropharmacology, 22, 573, 10.1016/0028-3908(83)90147-8 Hamon, 1984, Biochemical evidence for the 5-HT agonist properties of PAT (8-hydroxy-2-[di-N-propylamino]tetralin) in the rat brain, Eur. J. Pharmacol., 100, 263, 10.1016/0014-2999(84)90002-5 Hjorth, 1982, 8-Hydroxy-2-(di-N-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT receptor stimulating activity, J. Neural Transm., 55, 169, 10.1007/BF01276574 Hoyer, 1985, Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]cyanopindolol, [3H]-mesulergine and [3H]ketanserin, Eur. J. Pharmacol., 118, 13, 10.1016/0014-2999(85)90658-2 Hoyer, 1986, Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites, Brain Research, 376, 85, 10.1016/0006-8993(86)90902-9 Hunt, 1981, The interaction of indole derivatives with the serotonin receptor and non-dopaminergic circling behavior, 547 Leysen, 1981, Receptor binding profile of R 41468, a novel antagonist at 5-HT2 receptors, Life Sci., 28, 1015, 10.1016/0024-3205(81)90747-5 Leysen, 1982, [3H]Ketanserin (R 41468), a selective 3H-ligand for serotonin2 receptor binding sites, Mol. Pharmacol., 21, 301 Lucki, 1984, Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat, J. Pharmacol. Exp. Ther., 228, 133 Maurer, 1983, Multiple opiate receptor in human brain: an autoradiographic investigation, Life Sci., 33, 231, 10.1016/0024-3205(83)90485-X Meibach, 1980, Characterization and radioautography of [3H]LSD binding by rat brain slices in vitro: the effect of 5-hydroxytryptamine, Eur. J. Pharmacol., 67, 371, 10.1016/0014-2999(80)90178-8 Müller-Schweinitzer, 1983, Evidence for mediation by 5-HT2 receptors of 5-hydroxytryptamine-induced contraction of canine basilar artery, Naunyn-Schmiedeberg's Arch. Pharmacol., 324, 287, 10.1007/BF00502625 Nelson, 1980, Multiple types of serotonin receptors, 325 Nelson, 1983, 3H-Serotonin binding sites: pharmacological and species differences, 103 Oegren, 1979, Reevaluation of the indoleamino hypothesis of depression. Evidence for a reduction of functional activity of central 5-HT systems by antidepressant drugs, J. Neural Transm., 46, 85, 10.1007/BF01250331 Palacios, 1981, [3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors, Brain Research, 213, 277, 10.1016/0006-8993(81)90234-1 Palacios, 1983, The distribution of serotonin receptors in the human brain: high density of [3H]LSD binding sites in the raphénuclei of the brainstem, Brain Research, 274, 150, 10.1016/0006-8993(83)90531-0 Pazos, 1985, Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors, Brain Research, 346, 231, 10.1016/0006-8993(85)90857-1 Pazos, 1984, Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidences for species differences on brain serotonin-2 receptors, Eur. J. Pharmacol., 106, 531, 10.1016/0014-2999(84)90056-6 Pazos, 1984, The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site, Eur. J. Pharmacol., 106, 539, 10.1016/0014-2999(84)90057-8 Pazos, 1985, Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors, Brain Research, 346, 205, 10.1016/0006-8993(85)90856-X Peroutka, 1979, Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol, Mol. Pharmacol., 16, 687 Probst, 1984, Distribution of α2-adrenergic receptors in the human brainstem: an autoradiographic study using [3H]p-aminoclonidine, Eur. J. Pharmacol., 106, 477, 10.1016/0014-2999(84)90051-7 Reynolds, 1984, Reduced binding of3H-ketanserin to cortical 5-HT2 receptors in senile dementia of the Alzheimer type, Neurosci. Lett., 44, 47, 10.1016/0304-3940(84)90219-2 Richards, 1980, Supraependymal nerve fibres in human brain: correlative transmission and scanning electron microscopical and fluorescence histochemical studies, Neuroscience, 5, 1489, 10.1016/0306-4522(80)90011-1 Schotte, 1983, Characterization and regional distribution of serotonin S2-receptors in human brain, Brain Research, 276, 231, 10.1016/0006-8993(83)90729-1 Steinbush, 1981, Distribution of serotonin-immunoreactivity in the central nervous system of the rat — cell bodies and terminals, Neuroscience, 6, 557, 10.1016/0306-4522(81)90146-9 Unnerstall, 1982, Quantitative receptor autoradiography using [3H]Ultrofilm: application to multiple benzodiazepine receptors, J. Neurosci. Meth., 6, 59, 10.1016/0165-0270(82)90016-4 Yagaloff, 1985, 125I-LSD binds to a novel serotonergic site on rat choroid plexus epithelial cells, J. Neuroscience, 5, 3178, 10.1523/JNEUROSCI.05-12-03178.1985 Yap, 1983, Involvement of 5-HT2 receptors in the wet-dog shake behavior induced by 5-hydroxytryptophan in the rat, Neuropharmacology, 22, 801, 10.1016/0028-3908(83)90123-5