Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase
Tóm tắt
The inhibitory activity of 19 flavonoid molecules on cyclic AMP breakdown by a commercial beef heart phosphodiesterase preparation is reported. 7 compounds are active in the micromolar range, 2 of which have a potency equivalent to that of papaverine. Some structure activity relationships are drawn.
Tài liệu tham khảo
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