Bandage: interactive visualization of de novo genome assemblies

Bioinformatics (Oxford, England) - Tập 31 Số 20 - Trang 3350-3352 - 2015
Ryan R. Wick1, Mark B. Schultz1, Justin Zobel2, Kathryn E. Holt1
11 Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne and
22 Department of Computing and Information Systems, University of Melbourne, Parkville, Victoria, Australia

Tóm tắt

Abstract Summary: Although de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a Bioinformatics Application for Navigating De novo Assembly Graphs Easily) is a tool for visualizing assembly graphs with connections. Users can zoom in to specific areas of the graph and interact with it by moving nodes, adding labels, changing colors and extracting sequences. BLAST searches can be performed within the Bandage graphical user interface and the hits are displayed as highlights in the graph. By displaying connections between contigs, Bandage presents new possibilities for analyzing de novo assemblies that are not possible through investigation of contigs alone. Availability and implementation: Source code and binaries are freely available at https://github.com/rrwick/Bandage. Bandage is implemented in C++ and supported on Linux, OS X and Windows. A full feature list and screenshots are available at http://rrwick.github.io/Bandage. Contact:  [email protected] Supplementary information  :  Supplementary data are available at Bioinformatics online.

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Tài liệu tham khảo

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Thông tin xuất bản

Bioinformatics (Oxford, England)

Tập 31 Số 20

3350-3352

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