Insulin‐like growth factor‐1 signaling is responsible for cathepsin G‐induced aggregation of breast cancer MCF ‐7 cells
Tóm tắt
Cathepsin G (
Từ khóa
Tài liệu tham khảo
Nakajima K, 1979, Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the α1‐protease inhibitor reactive site, J Biol Chem, 254, 4027, 10.1016/S0021-9258(18)50690-6
Tomlinson JS, 2001, An intact overexpressed E‐cadherin/α, β‐catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma, Cancer Res, 61, 5231
Mendel DB, 2003, In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet‐derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship, Clin Cancer Res, 9, 327
Grollman AP, 1967, Inhibitors of protein synthesis. II. Mode of action of anisomycin, J Biol Chem, 242, 3226
Zielinska HA, 2015, Epithelial‐to‐mesenchymal transition in breast cancer: a role for insulin‐like growth factor I and insulin‐like growth factor‐binding protein 3?, Breast Cancer (Dove Med Press), 7, 9
Resnik JL, 1998, Elevated insulin‐like growth factor I receptor autophosphorylation and kinase activity in human breast cancer, Cancer Res, 58, 1159
Bartucci M, 2001, Differential insulin‐like growth factor I receptor signaling and function in estrogen receptor (ER)‐positive MCF‐7 and ER‐negative MDA‐MB‐231 breast cancer cells, Cancer Res, 61, 6747